1-(1-苯基乙基)环己醇 | 100862-95-1

• 分子结构分类: 有机化合物 - 有机氧化合物
• 中文名称: 1-(1-苯基乙基)环己醇
• 英文名称: 1-(1-phenylethyl)cyclohexanol
• 英文别名: 1-(1-phenylethyl)cyclohexan-1-ol；1-(1-Phenyl-aethyl)-cyclohexanol
• CAS: 100862-95-1
• 化学式: C₁₄H₂₀O
• 分子量: 204.312
• InChiKey: CGEXHLWWFGBDRP-UHFFFAOYSA-N

物化性质

• 沸点：
  82 °C(Press: 0.06 Torr)
• 密度：
  1.027 g/cm3

计算性质

• 辛醇/水分配系数(LogP)：
  3.5
• 重原子数：
  15
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.57
• 拓扑面积：
  20.2
• 氢给体数：
  1
• 氢受体数：
  1

反应信息

• 作为产物：
  描述：

  alkaline earth salt of/the/ methylsulfuric acid 在 氧气 作用下， 生成 1-(1-苯基乙基)环己醇
  参考文献：
  名称：

  Treibs; Schoellner, Chemische Berichte, 1958, vol. 91, p. 2282,2289

  摘要：

  DOI：

文献信息

• Tertiary Alkylations of Aldehydes, Ketones or Imines Using Benzylic Organoboronates and a Base Catalyst
  作者：Yukiya Sato、Kei Nakamura、Kenya Yabushita、Kazunori Nagao、Hirohisa Ohmiya

  DOI：10.1246/bcsj.20200122

  日期：2020.9.15

  The KHMDS-catalyzed tertiary alkylation of aldehydes, ketones or imines using tertiary benzylic organoboronates is reported. This protocol permitted the use of tertiary benzylic alkylboronates as t...

  报道了使用叔苄基有机硼酸酯的 KHMDS 催化的醛、酮或亚胺的叔烷基化反应。该协议允许使用叔苄基烷基硼酸盐作为...
• DTBB-Catalysed dilithiation of styrene and its methyl-derivatives: introduction of two electrophilic reagents
  作者：Miguel Yus、Pedro Martı́nez、David Guijarro

  DOI：10.1016/s0040-4020(01)01063-8

  日期：2001.12

  Pr2CO], in THF, at temperatures ranging from −78 to 0°C, gave, after hydrolysis, products 2 resulting from addition of lithium to the olefinic double bond and successive trapping with the electrophilic reagent. When a carbonyl compound was used as electrophile, mixtures of the monoaddition–reduction compounds 3 and 4 were obtained as by-products, which could be easily separated from the diaddition

  苯乙烯和一些甲基取代的苯乙烯1与锂和催化量的4,4'-二叔丁基联苯（DTBB）在几种亲电试剂[Me 3 SiCl，Me 2 CO，Et 2 CO， （CH 2）5 CO，Pr 2 CO]在THF中，于-78至0°C的温度范围内，水解后得到由锂加成至烯烃双键并随后用亲电子试剂捕获而得到的产物2。当羰基化合物用作亲电试剂时，单加成还原化合物3和4的混合物获得的副产物可以容易地与二价产物2分离。
• Exploration of the diastereoselectivity in an unusual Grignard reaction and its application towards the synthesis of styryl lactones 7-epi-(+)-goniodiol and 8-epi-(−)-goniodiol
  作者：Subhash P. Chavan、Harshali S. Khatod、Tamal Das、Kumar Vanka

  DOI：10.1039/c6ra03192g

  日期：——

  chain secondary alcohols possessing a terminal olefin, which are synthetically important intermediates. As an application of this method, the diastereoselective synthesis of styryl lactones viz. 7-epi-(+)-goniodiol (29) and 8-epi-(−)-goniodiol (30) has been achieved.

  探索了不寻常的非对映选择性格氏试剂，其中格氏试剂衍生自1，n-二卤代烷烃。由于在苄基位置上与丙酮酸酯相邻的季中心的存在而引起的空间偏向负责以几乎定量的产率形成分子内还原的产物。这种位阻是多种芳香族和脂肪族酯类所观察到的非对映选择性的原因。不寻常的格氏反应可提供具有末端烯烃的长链仲醇，这是合成上重要的中间体。作为该方法的应用，苯乙烯基内酯的非对映选择性合成。7- Epi -（+）-goniodiol（29）和8-epi -（-）-goniodiol（30）已经实现。
• Generation of allylic and benzylic organolithium reagents from the corresponding ester, amide, carbonate, carbamate and urea derivatives
  作者：Emma Alonso、David Guijarro、Pedro Martínez、Diego J Ramón、Miguel Yus

  DOI：10.1016/s0040-4020(99)00610-9

  日期：1999.9

  The reaction of different allylic and benzylic non-enolisable esters or amides (1), carbonates (4), carbamates (6, 7) and ureas (8) with an excess of lithium powder and a catalytic amount of naphthalene (10%) in the presence of an electrophile [iPrCHO, tBuCHO, PhCHO, Me2CO, Et2CO, (CH2)(5)CO, Ph2CO, MeSiCl] in THF at different temperatures (-78, -30 or 0 degrees C) leads, after hydrolysis with water, to the corresponding allylated or benzylated products (2). (C) 1999 Elsevier Science Ltd. All rights reserved.
• Pigment dispersion and ink composition using the same
  申请人：FUJIFILM Corporation

  公开号：EP2130881B1

  公开（公告）日：2011-11-09