1-(2-氨基苯基)-2-溴乙酮 | 58585-01-6

• 分子结构分类: 有机化合物 - 有机氧化合物
• 中文名称: 1-(2-氨基苯基)-2-溴乙酮
• 中文别名: 2-氨基-2'-溴苯乙酮
• 英文名称: 2-amino-1-(2-bromophenyl)ethanone
• 英文别名: 2-Amino-2'-bromoacetophenone
• CAS: 58585-01-6
• 化学式: C₈H₈BrNO
• mdl: MFCD09752959
• 分子量: 214.062
• InChiKey: YURHFZWNMZMZBM-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.4
• 重原子数：
  11
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.125
• 拓扑面积：
  43.1
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  在 碘苯二乙酸 作用下， 以 二氯甲烷 为溶剂， 以81%的产率得到1-(2-氨基苯基)-2-溴乙酮
  参考文献：
  名称：

  通过具有高价碘试剂的Umpolung对酮进行灵活的立体选择性官能化

  摘要：

  由于此类产品具有广泛的生物学重要性，因此羰基化合物在α位上的功能化作为合成途径已引起广泛关注。通过极性反转或“极性”，我们在这里表明典型的亲核试剂，例如氧，氮，甚至碳亲核试剂，在将它们束缚到烯醇醚后，可以用于加成反应。我们的发现可以进行新颖的逆合成规划，并可以快速组装以前只能通过多步序列访问的结构。

  DOI：

  10.1002/anie.201400405

文献信息

• Organic light-emitting material and manufacturing method thereof, and organic light-emitting device
  申请人：WUHAN CHINA STAR OPTOELECTRONICS SEMICONDUCTOR DISPLAY TECHNOLOGY CO., LTD.

  公开号：US11254687B2

  公开（公告）日：2022-02-22

  An organic light-emitting material and the manufacturing method thereof, and an organic light-emitting device are disclosed. The organic light-emitting material includes a benzophenanthrene derivative, which has good planarity and strong visible π-π* absorption ability and has a high quantum yield of blue light-emitting capability as well. Therefore, a benzophenanthrene derivative having a large π-conjugated system has high-efficiency electron transporting properties, and its high electron-withdrawing group increases electron mobility rate and effectively improve the light-emitting efficiency of the organic light emitting device.

  本发明公开了一种有机发光材料及其制造方法，以及一种有机发光器件。该有机发光材料包括一种二苯并菲衍生物，该衍生物具有良好的平面性和较强的可见光π-π*吸收能力，并具有较高的量子产率和蓝光发光能力。因此，具有大π共轭体系的苯并菲衍生物具有高效的电子传输特性，其高吸收电子基团可提高电子迁移率，有效提高有机发光器件的发光效率。
• Process for preparing 2-cyanoimidazole compounds
  申请人：ISHIHARA SANGYO KAISHA LTD.

  公开号：EP0653421B1

  公开（公告）日：1997-01-15
• ORGANIC LIGHT-EMITTING MATERIAL AND MANUFACTURING METHOD THEREOF, AND ORGANIC LIGHT-EMITTING DEVICE
  申请人：WUHAN CHINA STAR OPTOELECTRONICS SEMICONDUCTOR DISPLAY TECHNOLOGY CO., LTD.

  公开号：US20210403481A1

  公开（公告）日：2021-12-30

  An organic light-emitting material and the manufacturing method thereof, and an organic light-emitting device are disclosed. The organic light-emitting material includes a benzophenanthrene derivative, which has good planarity and strong visible π-π* absorption ability and has a high quantum yield of blue light-emitting capability as well. Therefore, a benzophenanthrene derivative having a large π-conjugated system has high-efficiency electron transporting properties, and its high electron-withdrawing group increases electron mobility rate and effectively improve the light-emitting efficiency of the organic light emitting device.
• SUMO INHIBITOR COMPOUNDS AND USES THEREOF
  申请人：SUVALENT THERAPEUTICS, INC.

  公开号：US20220177488A1

  公开（公告）日：2022-06-09

  The present invention relates to compounds and compositions capable of acting as inhibitors of small ubiquitin-like modifier (SUMO) family of proteins. The compounds and compositions may be used in the treatment of cancer. There are disclosed, inter alia, methods of inhibiting an E1 enzyme, and compounds useful for inhibiting an E1 enzyme.
• US5552557A
  申请人：——

  公开号：US5552557A

  公开（公告）日：1996-09-03