1-(6-溴己-1-烯基)-4-甲氧基苯 | 141773-79-7

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯酚醚
• 中文名称: 1-(6-溴己-1-烯基)-4-甲氧基苯
• 英文名称: 1-(6-Bromohex-1-EN-1-YL)-4-methoxybenzene
• 英文别名: 1-(6-bromohex-1-enyl)-4-methoxybenzene
• CAS: 141773-79-7
• 化学式: C₁₃H₁₇BrO
• 分子量: 269.181
• InChiKey: JJVIHVROEQJOHM-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.3
• 重原子数：
  15
• 可旋转键数：
  6
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.38
• 拓扑面积：
  9.2
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  1H-1,2,4-三唑 、 1-(6-溴己-1-烯基)-4-甲氧基苯 在 potassium carbonate 作用下， 以 丙酮 为溶剂， 反应 6.0h， 以81%的产率得到1-[(E)-6-(4-Methoxy-phenyl)-hex-5-enyl]-1H-[1,2,4]triazole
  参考文献：
  名称：

  Studies on the Wittig Reaction (XXX): Stereoselective Synthesis and Bioactivity of 1-Aryl-6-(1,2,4-Triazol-1-Yl)-1-Hexenes

  摘要：

  Twelve 1-aryl-6-(1,2,4-triazol-1-yl)-1-hexenes 4 were synthesized by N-alkylation of alkenyl bromides 3, which were obtained by the Wittig reaction of 5-hydroxypentyltriphenylphosphonium bromide 1 with various aromatic aldehydes and subsequent bromination of the resulting alkenyl alcohols 2. The preliminary bioassay results showed that new compounds 4 were active to file plant diseases.

  DOI：

  10.1080/10426500008082398
• 作为产物：
  描述：

  5-hydroxypentyltriphenylphosphonium bromide 在 吡啶 、 正丁基锂 、 三溴化磷 作用下， 以 四氢呋喃 、 乙醚 为溶剂， 反应 9.17h， 生成 1-(6-溴己-1-烯基)-4-甲氧基苯
  参考文献：
  名称：

  Studies on the Wittig Reaction (XXX): Stereoselective Synthesis and Bioactivity of 1-Aryl-6-(1,2,4-Triazol-1-Yl)-1-Hexenes

  摘要：

  Twelve 1-aryl-6-(1,2,4-triazol-1-yl)-1-hexenes 4 were synthesized by N-alkylation of alkenyl bromides 3, which were obtained by the Wittig reaction of 5-hydroxypentyltriphenylphosphonium bromide 1 with various aromatic aldehydes and subsequent bromination of the resulting alkenyl alcohols 2. The preliminary bioassay results showed that new compounds 4 were active to file plant diseases.

  DOI：

  10.1080/10426500008082398

文献信息

• US5352701A
  申请人：——

  公开号：US5352701A

  公开（公告）日：1994-10-04
• US5541202A
  申请人：——

  公开号：US5541202A

  公开（公告）日：1996-07-30
• US5624943A
  申请人：——

  公开号：US5624943A

  公开（公告）日：1997-04-29
• Studies on the Wittig Reaction (XXX): Stereoselective Synthesis and Bioactivity of 1-Aryl-6-(1,2,4-Triazol-1-Yl)-1-Hexenes
  作者：Shui-Ming Lu、Wen-Jing Xiao、Wen-Fang Huang、Tian-Jie Wu

  DOI：10.1080/10426500008082398

  日期：2000.1.1

  Twelve 1-aryl-6-(1,2,4-triazol-1-yl)-1-hexenes 4 were synthesized by N-alkylation of alkenyl bromides 3, which were obtained by the Wittig reaction of 5-hydroxypentyltriphenylphosphonium bromide 1 with various aromatic aldehydes and subsequent bromination of the resulting alkenyl alcohols 2. The preliminary bioassay results showed that new compounds 4 were active to file plant diseases.