11-乙基-8-(2-羟基乙基)-5-甲基-5,11-二氢-6H-二吡啶并[3,2-B:2',3'-E][1,4]二氮杂卓-6-酮 | 211750-50-4

分子结构分类

有机化合物 - 有机氮化合物

中文名称

11-乙基-8-(2-羟基乙基)-5-甲基-5,11-二氢-6H-二吡啶并[3,2-B:2',3'-E][1,4]二氮杂卓-6-酮

中文别名

——

英文名称

BIRK 122

英文别名

5-ethyl-2-(2-hydroxyethyl)-10-methyl-5,10-dihydro-4,5,6,10-tetraazadibenzo[a,d]cyclohepten-11-one；5,11-dihydro-11-ethyl-8-(2-hydroxyethyl)-5-methyl-6H-dipyrido-[3,2-b:2',3'-e][1,4]diazepin-6-one；11-ethyl-8-(2-hydroxyethyl)-5-methyl-5,11-dihydro-6H-dipyrido[2,3-e:3',2'-b][1,4]diazepin-6-one；11-ethyl-5,11-dihydro-8-(2-hydroxyethyl)-5-methyl-6H-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one；5,11-dihydro-11-ethyl-8-(2-hydroxyethyl)-5-methyl-6H-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one；11-Ethyl-8-(2-hydroxyethyl)-5-methyl-5,11-dihydro-6h-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one；2-ethyl-13-(2-hydroxyethyl)-9-methyl-2,4,9,15-tetrazatricyclo[9.4.0.03,8]pentadeca-1(11),3(8),4,6,12,14-hexaen-10-one

11-乙基-8-(2-羟基乙基)-5-甲基-5,11-二氢-6H-二吡啶并[3,2-B:2',3'-E][1,4]二氮杂卓-6-酮化学式

CAS

211750-50-4

化学式

C₁₆H₁₈N₄O₂

mdl

——

分子量

298.345

InChiKey

LSDLBGOYTYAGQC-UHFFFAOYSA-N

BEILSTEIN

——

EINECS

——

计算性质

辛醇/水分配系数(LogP)：

1.2
重原子数：

22
可旋转键数：

3
环数：

3.0
sp3杂化的碳原子比例：

0.31
拓扑面积：

69.6
氢给体数：

1
氢受体数：

5

SDS

SDS：2daa7a75a4362001d9a06442983535ea

查看

上下游信息

上游原料

中文名称	英文名称	CAS号	化学式	分子量
——	11-ethyl-5-methyl-8-(2-propenyl)-5,11-dihydro-6H-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one	380378-91-6	C₁₇H₁₈N₄O	294.356
8-溴-11-乙基-5-甲基-5,11-二氢-6H-二吡啶并[3,2-B:2',3'-E][1,4]二氮杂卓-6-酮	2-bromo-5-ethyl-10-methyl-5,10-dihydro-4,5,6,10-tetraazadibenzo[a,d]cyclohepten-11-one	162109-00-4	C₁₄H₁₃BrN₄O	333.187
8-溴-11-乙基-5,11-二氢-6H-二吡啶并[3,2-b:2',3'-e][1,4]二氮杂卓-6-酮	5,11-dihydro-11-ethyl-8-bromo-6H-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one	134698-42-3	C₁₃H₁₁BrN₄O	319.161

下游产品

中文名称	英文名称	CAS号	化学式	分子量
——	4-[2-(2-Ethyl-9-methyl-10-oxo-2,4,9,15-tetrazatricyclo[9.4.0.03,8]pentadeca-1(11),3(8),4,6,12,14-hexaen-13-yl)ethoxy]benzoic acid	——	C₂₃H₂₂N₄O₄	418.452
——	11-ethyl-5,11-dihydro-5-methyl-8-{2-[4-(4-pyridinyl)phenoxy]ethyl}-6H-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one	627905-65-1	C₂₇H₂₅N₅O₂	451.528
——	11-ethyl-8-[2-(4-formyl-2-methylphenoxy)ethyl]-5,11-dihydro-5-methyl-6H-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one	627906-73-4	C₂₄H₂₄N₄O₃	416.48
——	6-[2-(2-Ethyl-9-methyl-10-oxo-2,4,9,15-tetrazatricyclo[9.4.0.03,8]pentadeca-1(11),3(8),4,6,12,14-hexaen-13-yl)ethoxy]naphthalene-2-carboxylic acid	——	C₂₇H₂₄N₄O₄	468.512
——	8-[2-(4-bromo-2-methylphenoxy)ethyl]-11-ethyl-5,11-dihydro-5-methyl-6H-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one	627906-76-7	C₂₃H₂₃BrN₄O₂	467.365
——	2-[4-[2-(2-Ethyl-9-methyl-10-oxo-2,4,9,15-tetrazatricyclo[9.4.0.03,8]pentadeca-1(11),3(8),4,6,12,14-hexaen-13-yl)ethoxy]-3-methylphenyl]acetic acid	——	C₂₅H₂₆N₄O₄	446.506
——	Methyl 6-[2-(2-ethyl-9-methyl-10-oxo-2,4,9,15-tetrazatricyclo[9.4.0.03,8]pentadeca-1(11),3(8),4,6,12,14-hexaen-13-yl)ethoxy]naphthalene-2-carboxylate	497068-81-2	C₂₈H₂₆N₄O₄	482.539
——	6-[2-(2-Ethyl-9-methyl-10-oxo-2,4,9,15-tetrazatricyclo[9.4.0.03,8]pentadeca-1(11),3(8),4,6,12,14-hexaen-13-yl)ethoxy]naphthalene-1-carboxylic acid	——	C₂₇H₂₄N₄O₄	468.512
——	4-[2-(11-ethyl-6,11-dihydro-5-methyl-6-oxo-5H-dipyrido[3,2-b:2',3'-e][1,4]diazepin-8-yl)ethoxy]-3-methylbenzoic acid	607707-35-7	C₂₄H₂₄N₄O₄	432.479
——	3-[4-[2-(2-Ethyl-9-methyl-10-oxo-2,4,9,15-tetrazatricyclo[9.4.0.03,8]pentadeca-1(11),3(8),4,6,12,14-hexaen-13-yl)ethoxy]-3-methylphenyl]propanoic acid	——	C₂₆H₂₈N₄O₄	460.533
——	methyl 4-[2-(11-ethyl-5-methyl-6-oxo-6,11-dihydro-5H-dipyrido[2,3-e:3',2'-b][1,4]diazepin-8-yl)ethoxy]-3-methylbenzoate	607707-58-4	C₂₅H₂₆N₄O₄	446.506
——	3-Ethyl-4-[2-(2-ethyl-9-methyl-10-oxo-2,4,9,15-tetrazatricyclo[9.4.0.03,8]pentadeca-1(11),3(8),4,6,12,14-hexaen-13-yl)ethoxy]benzoic acid	——	C₂₅H₂₆N₄O₄	446.506
——	5-[2-(2-Ethyl-9-methyl-10-oxo-2,4,9,15-tetrazatricyclo[9.4.0.03,8]pentadeca-1(11),3(8),4,6,12,14-hexaen-13-yl)ethoxy]naphthalene-1-carboxylic acid	——	C₂₇H₂₄N₄O₄	468.512
——	1-Naphthalenecarboxylic acid, 4-[2-(11-ethyl-6,11-dihydro-5-methyl-6-oxo-5H-dipyrido[2,3-e:3',2'-b][1,4]diazepin-8-yl)ethoxy]-	——	C₂₇H₂₄N₄O₄	468.512
——	2-Ethyl-9-methyl-13-(2-quinolin-4-yloxyethyl)-2,4,9,15-tetrazatricyclo[9.4.0.03,8]pentadeca-1(11),3(8),4,6,12,14-hexaen-10-one	1190412-78-2	C₂₅H₂₃N₅O₂	431.424
——	5,11-dihydro-11-ethyl-5-methyl-8-{2-(4-quinolinyloxy)[benzene-(14)C(U)]ethyl}-6H-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one	1190412-71-5	C₂₅H₂₃N₅O₂	437.424
——	BILR 402	380378-84-7	C₂₅H₂₃N₅O₂	425.49
——	methyl 3'-[2-(11-ethyl-6,11-dihydro-5-methyl-6-oxo-5H-dipyrido[3,2-b:2',3'-e][1,4]diazepin-8-yl)ethoxy]-[1,1'-biphenyl]-4-carboxylate	627906-78-9	C₃₀H₂₈N₄O₄	508.577
——	3-Bromo-4-[2-(2-ethyl-9-methyl-10-oxo-2,4,9,15-tetrazatricyclo[9.4.0.03,8]pentadeca-1(11),3(8),4,6,12,14-hexaen-13-yl)ethoxy]benzoic acid	——	C₂₃H₂₁BrN₄O₄	497.348
——	1,1-dimethylethyl N-{4-[2-(11-ethyl-6,11-dihydro-5-methyl-6-oxo-5H-dipyrido[3,2-b:2',3'-e][1,4]diazepin-8-yl)ethoxy]-3-methylphenyl}carbamate	627906-83-6	C₂₈H₃₃N₅O₄	503.601
——	[4-[2-(2-Ethyl-9-methyl-10-oxo-2,4,9,15-tetrazatricyclo[9.4.0.03,8]pentadeca-1(11),3(8),4,6,12,14-hexaen-13-yl)ethoxy]-3-methylphenyl]phosphonic acid	1422738-78-0	C₂₃H₂₅N₄O₅P	468.449
——	Methyl 3-ethyl-4-[2-(2-ethyl-9-methyl-10-oxo-2,4,9,15-tetrazatricyclo[9.4.0.03,8]pentadeca-1(11),3(8),4,6,12,14-hexaen-13-yl)ethoxy]benzoate	607707-26-6	C₂₆H₂₈N₄O₄	460.533
——	methyl 4'-[2-(11-ethyl-6,11-dihydro-5-methyl-6-oxo-5H-dipyrido[3,2-b:2',3'-e][1,4]diazepin-8-yl)ethoxy]-3'-methyl-(1,1'-biphenyl)-3-carboxylate	627906-51-8	C₃₁H₃₀N₄O₄	522.604
——	BILR 355	380378-81-4	C₂₅H₂₃N₅O₃	441.489
——	2-ethyl-9-methyl-13-[2-(1-oxidoquinolin-1-ium-4-yl)oxyethyl]-2,4,9,15-tetrazatricyclo[9.4.0.03,8]pentadeca-1(11),3(8),4,6,12,14-hexaen-10-one	1190412-69-1	C₂₅H₂₃N₅O₃	447.423
——	5,11-dihydro-11-ethyl-5-methyl-8-{2-{(1-oxido-4-quinolinyl)[benzene-(14)C(U)]oxy}-ethyl}-6H-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one	1190412-66-8	C₂₅H₂₃N₅O₃	453.423
——	BILR 516	1040924-47-7	C₂₅H₂₃N₅O₃	441.489
——	11-Ethyl-5,11-dihydro-5-methyl-8-{2-[2-methyl-4-(4-oxazolyl)phenoxy]ethyl}-6H-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one	627905-74-2	C₂₆H₂₅N₅O₃	455.516
——	5,11-dihydro-8-{2-{(2,3-dihydro-1-oxo-1H-isoindol-4-yl)oxy}ethyl}-11-ethyl-5-methyl-6H-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one	697800-74-1	C₂₄H₂₃N₅O₃	429.478
——	13-[2-(4-Diethoxyphosphoryl-2-methylphenoxy)ethyl]-2-ethyl-9-methyl-2,4,9,15-tetrazatricyclo[9.4.0.03,8]pentadeca-1(11),3(8),4,6,12,14-hexaen-10-one	1422738-77-9	C₂₇H₃₃N₄O₅P	524.557
——	8-{2-[4-(2-Amino-4-thiazolyl)-2-methylphenoxy]ethyl}-11-ethyl-5,11-dihydro-5-methyl-6H-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one	627905-68-4	C₂₆H₂₆N₆O₂S	486.597
——	11-ethyl-5,11-dihydro-8-{2-[4-(5-formyl-2-furanyl)-2-methylphenoxy]ethyl}-5-methyl-6H-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one	627906-62-1	C₂₈H₂₆N₄O₄	482.539
——	5,11-dihydro-11-ethyl-5-methyl-8-{2-{(1,2,3,4-tetrahydro-2-oxo-5-quinazolinyl)oxy}ethyl}-6H-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one	697800-85-4	C₂₄H₂₄N₆O₃	444.493
——	ethyl 5-{4-[2-(11-ethyl-6,11-dihydro-5-methyl-6-oxo-5H-dipyrido[3,2-b:2',3'-e][1,4]diazepin-8-yl)ethoxy]phenyl}-2-methyl-3-furanecarboxylate	627906-64-3	C₃₀H₃₀N₄O₅	526.592
——	ethyl 3-{4-[2-(11-ethyl-6,11-dihydro-5-methyl-6-oxo-5H-dipyrido[3,2-b:2',3'-e][1,4]diazepin-8-yl)ethoxy]-3-methylphenyl}-5-isoxazolecarboxylate	627906-58-5	C₂₉H₂₉N₅O₅	527.58
——	11-ethyl-5,11-dihydro-8-{2-{2-methyl-4-[1-(triphenylmethyl)-1H-imidazol-4-yl]phenoxy}ethyl}-5-methyl-6H-dipyrido[3,2-b:2',3'-e][1,4]diazepin-6-one	627906-68-7	C₄₅H₄₀N₆O₂	696.852

反应信息

作为反应物：