11-氨基十一烷酸四甲基铵盐 | 947601-83-4

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 中文名称: 11-氨基十一烷酸四甲基铵盐
• 英文名称: Tetramethylammonium 11-aminoundecanoate
• 英文别名: 11-aminoundecanoate;tetramethylazanium
• CAS: 947601-83-4
• 化学式: C15H34N2O2
• 分子量: 274.44
• InChiKey: VREIIGDEUQSHDP-UHFFFAOYSA-M

计算性质

• 辛醇/水分配系数(LogP)：
  1.53
• 重原子数：
  19
• 可旋转键数：
  9
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.93
• 拓扑面积：
  66.2
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  11-氨基十一酸 、 四甲基氢氧化铵 以 四氢呋喃 为溶剂， 生成 11-氨基十一烷酸四甲基铵盐
  参考文献：
  名称：

  COMPOSITE PARTICLES

  摘要：

  本发明公开了复合粒子及其合成方法，特别是公开了一种包括介电组分、磁性组分和金壳的复合粒子的合成方法。本发明还公开了使用本发明的复合粒子检测目标化合物的方法。同时，本发明还公开了可以通过外部磁场操纵的光子晶体，其中包括本发明的复合粒子。

  公开号：

  US20100129793A1

文献信息

• COMPOSITE PARTICLES
  申请人：Mirkin Chad A.

  公开号：US20100129793A1

  公开（公告）日：2010-05-27

  Composite particles and methods of synthesizing a composite particle are disclosed, in particular, methods of synthesizing a composite particle comprising a dielectric component, a magnetic component, and a gold shell are disclosed. Further disclosed herein are methods of detecting a target compound using the composite particles of the present invention. Also disclosed are photonic crystals that can be manipulated with an external magnetic field comprising the composite particles of the present invention.

  本发明公开了复合粒子及其合成方法，特别是公开了一种包括介电组分、磁性组分和金壳的复合粒子的合成方法。本发明还公开了使用本发明的复合粒子检测目标化合物的方法。同时，本发明还公开了可以通过外部磁场操纵的光子晶体，其中包括本发明的复合粒子。
• Engineered nanoparticles for aqueous applications
  申请人：WASHINGTON UNIVERSITY

  公开号：US11148119B2

  公开（公告）日：2021-10-19

  Coated iron oxide (10) nanocrystal structures, superparamagnetic 10 nanoparticles, methods for synthesizing coated 10 nanocrystal structures, and methods for synthesizing superparamagnetic 10 nanoparticles are described herein. A coated 10 nanocrystal structure may comprise an iron oxide core, a manganese ferrite shell layer surrounding the core, and a bilayer coating surrounding the shell layer. The bilayer coating may include an inner oleic acid layer surrounding the shell layer and an outer layer surrounding the inner oleic acid layer.

  本文描述了涂层氧化铁（10）纳米晶体结构、超顺磁性 10 纳米粒子、合成涂层 10 纳米晶体结构的方法以及合成超顺磁性 10 纳米粒子的方法。有涂层的 10 纳米晶体结构可包括氧化铁内核、围绕内核的锰铁氧体外壳层和围绕外壳层的双层涂层。双层涂层可包括环绕外壳层的油酸内层和环绕油酸内层的外层。
• DIVALENT-METAL COATED NANOPARTICLES FOR DELIVERY OF COMPOSITIONS INTO THE CENTRAL NERVOUS SYSTEM BY NASAL INSUFFLATION
  申请人：Sanchez-Ramos Juan

  公开号：US20140248364A1

  公开（公告）日：2014-09-04

  The compositions and methods of the disclosure particularly target the divalent metal transporter expressed on olfactory nerve terminals to transport divalent cation-coated or cation-containing nanoparticles to all regions of brain. It has been found that such divalent cation-containing nanoparticles, including those nanoparticles comprising manganese have affinity for the metal transport receptor proteins. Although this receptor has particular affinity for manganese, it is contemplated that other divalent ions, including magnesium, calcium, and the like may also be bound to such receptors leading to transport of the nanoparticles into the intracellular cytoplasm. Nanoparticles have been developed, therefore, as vehicles for parenteral delivery of genes, proteins and drugs. The present disclosure encompasses embodiments of nanoparticle-based compositions and methods for the use thereof for the delivery of genes, oligonucleotides, including but not limited to small interfering RNA, and other small molecule drugs, into the brain by nasal insufflation.
• MANGANESE ION COATED NANOPARTICLES FOR DELIVERY OF COMPOSITIONS INTO THE CENTRAL NERVOUS SYSTEM BY NASAL INSUFFLATION
  申请人：Sanchez-Ramos Juan

  公开号：US20160312222A1

  公开（公告）日：2016-10-27

  The compositions and methods of the disclosure particularly target the divalent metal transporter expressed on olfactory nerve terminals to transport divalent cation-coated or cation-containing nanoparticles to all regions of brain. It has been found that such divalent cation-containing nanoparticles, including those nanoparticles comprising manganese have affinity for the metal transport receptor proteins. Although this receptor has particular affinity for manganese, it is contemplated that other divalent ions, including magnesium, calcium, and the like may also be bound to such receptors leading to transport of the nanoparticles into the intracellular cytoplasm. Nanoparticles have been developed, therefore, as vehicles for parenteral delivery of genes, proteins and drugs. The present disclosure encompasses embodiments of nanoparticle-based compositions and methods for the use thereof for the delivery of genes, oligonucleotides, including but not limited to small interfering RNA, and other small molecule drugs, into the brain by nasal insufflation.
• ENGINEERED NANOPARTICLES FOR AQUEOUS APPLICATIONS
  申请人：WASHINGTON UNIVERSITY

  公开号：US20180280923A1

  公开（公告）日：2018-10-04

  Coated iron oxide (10) nanocrystal structures, superparamagnetic 10 nanoparticles, methods for synthesizing coated 10 nanocrystal structures, and methods for synthesizing superparamagnetic 10 nanoparticles are described herein. A coated 10 nanocrystal structure may comprise an iron oxide core, a manganese ferrite shell layer surrounding the core, and a bilayer coating surrounding the shell layer. The bilayer coating may include an inner oleic acid layer surrounding the shell layer and an outer layer surrounding the inner oleic acid layer.