1H-吲哚-2,5-二醇 | 321884-36-0

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吲哚及其衍生物
• 中文名称: 1H-吲哚-2,5-二醇
• 英文名称: 1H-Indole-2,5-diol
• CAS: 321884-36-0
• 化学式: C₈H₇NO₂
• 分子量: 149.15
• InChiKey: WCMNKJSRZUKXDL-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.7
• 重原子数：
  11
• 可旋转键数：
  0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  56.2
• 氢给体数：
  3
• 氢受体数：
  2

文献信息

• METHODS AND SYSTEMS USING INTEGRATED METABOLOMICS AND PHARMACOKINETICS FOR MULTI-COMPONENT DRUG EVALUATION
  申请人：Jia Wei

  公开号：US20140024132A1

  公开（公告）日：2014-01-23

  Disclosed are methods and systems for identifying biochemical changes in a subject in response to administration of a multi-component therapeutic and one or more active ingredients in the multi-component therapeutic. The methods and systems of the invention may be used to elucidate the interaction of the biological system's genome with its environments, and in the pharmacokinetic, pharmacodynamic and toxicology analysis of multi-component therapeutics. The metabolomics methods and systems of the invention can also be used in studies of plant derived agents to demonstrate biochemical alterations in response to the dynamic multi-component intervention.
• [EN] METHODS AND SYSTEMS USING INTEGRATED METABOLOMICS AND PHARMACOKINETICS FOR MULTI-COMPONENT DRUG EVALUATION<br/>[FR] PROCÉDÉS ET SYSTÈMES INTÉGRANT MÉTABOLOMIQUE ET PHARMACOCINÉTIQUE EN VUE DE L'ÉVALUATION D'UN MÉDICAMENT MULTICOMPOSANT
  申请人：UNIV NORTH CAROLINA AT GREENSBORO

  公开号：WO2011113066A1

  公开（公告）日：2011-09-15

  Disclosed are methods and systems for identifying biochemical changes in a subject in response to administration of a multi-component therapeutic and one or more active ingredients in the multi-component therapeutic. The methods and systems of the invention may be used to elucidate the interaction of the biological system's genome with its environments, and in the pharmacokinetic, pharmacodynamic and toxicology analysis of multi-component therapeutics. The metabolomics methods and systems of the invention can also be used in studies of plant derived agents to demonstrate biochemical alterations in response to the dynamic multi-component intervention.