2,2'-氧基二丁烷-1-醇 | 55011-26-2

• 分子结构分类: 有机化合物 - 有机氧化合物
• 中文名称: 2,2'-氧基二丁烷-1-醇
• 英文名称: 2,2'-Oxybisbutan-1-ol
• 英文别名: 2-(1-hydroxybutan-2-yloxy)butan-1-ol
• CAS: 55011-26-2
• 化学式: C₈H₁₈O₃
• 分子量: 162.23
• InChiKey: YLGKTKNKMPOCBY-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.6
• 重原子数：
  11
• 可旋转键数：
  6
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  49.7
• 氢给体数：
  2
• 氢受体数：
  3

文献信息

• [EN] SYNTHETIC OLIGOGLUCOSAMINES FOR IMPROVEMENT OF PLANT GROWTH AND YIELD<br/>[FR] OLIGOGLUCOSAMINES SYNTHÉTIQUES POUR L'AMÉLIORATION DE LA CROISSANCE ET DU RENDEMENT DE VÉGÉTAUX
  申请人：DU PONT

  公开号：WO2015130893A1

  公开（公告）日：2015-09-03

  The disclosure provides formulations comprising synthetic oligoglucosamines and methods for improving plant growth and crop yield therewith. These formulations may be applied to propagating materials, including seeds and other regenerable plant parts, including cuttings, bulbs, rhizomes and tubers. They may also be applied to foliage, or soil either prior to or following planting of propagating materials. Such applications may be made alone or in combination with fungicides, insecticides, nematicides and other agricultural agents used to improve plant growth and crop yield.

  该披露提供了包含合成寡聚葡聚糖胺的配方，以及利用这些配方改善植物生长和作物产量的方法。这些配方可以应用于繁殖材料，包括种子和其他可再生植物部分，如插条、球茎、根茎和块茎。它们也可以应用于叶片或土壤，无论是在种植繁殖材料之前还是之后。这些应用可以单独进行，也可以与杀菌剂、杀虫剂、线虫杀灭剂和其他用于改善植物生长和作物产量的农业药剂结合使用。
• COMPLEXING AGENTS FOR COMPOSITIONS CONTAINING INCLUSION COMPLEXES
  申请人：California Institute of Technology

  公开号：US20170049903A1

  公开（公告）日：2017-02-23

  The invention provides a composition containing particulate composite of a polymer and a therapeutic agent. The composition also contains a complexing agent. The polymer interacts with the complexing agent in a host-guest or a guest-host interaction to form an inclusion complex. A therapeutic composition of the invention may be used to deliver the therapeutic agent and to treat various disorders. Both the polymer of the particulate composite and the complexing agent may be used to introduce functionality into the therapeutic composition. The invention also relates to a method of preparing a composition. The method combines a therapeutic agent, a polymer having host or guest functionality, and a complexing agent having guest or host functionality to form the therapeutic composition. The complexing agent forms an inclusion complex with the polymer. The invention also relates to a method of delivering a therapeutic agent. According to the method, a therapeutically effective amount of a therapeutic composition of the invention is administered to a mammal (e.g. person or animal) in recognized need of the therapeutic. Also disclosed are compounds having the formula:

  该发明提供了一种含有聚合物和治疗剂的颗粒复合物的组合物。该组合物还包含一种络合剂。聚合物与络合剂在宿主-客体或客体-宿主相互作用中相互作用，形成包含复合物。该发明的治疗组合物可用于传递治疗剂并治疗各种疾病。颗粒复合物的聚合物和络合剂均可用于向治疗组合物引入功能。该发明还涉及一种制备组合物的方法。该方法将治疗剂、具有宿主或客体功能的聚合物以及具有客体或宿主功能的络合剂结合在一起，形成治疗组合物。络合剂与聚合物形成包含复合物。该发明还涉及一种传递治疗剂的方法。根据该方法，在确实需要治疗的已知需要治疗的哺乳动物（例如人或动物）体内给予该发明的治疗组合物的治疗有效量。还披露了具有以下结构的化合物：
• LINEAR CYCLODEXTRIN COPOLYMERS
  申请人：California Institute of Technology

  公开号：US20180030207A1

  公开（公告）日：2018-02-01

  Linear cyclodextrin copolymers and linear oxidized cyclodextrin copolymers containing an unoxidized and/or an oxidized cyclodextrin moiety integrated into the polymer backbone are described. Methods of preparing such copolymers are also described. The linear cyclodextrin copolymer and linear oxidized cyclodextrin copolymer of the invention may be used as a delivery vehicle of various therapeutic agents.

  本发明涉及线性环糊精共聚物和线性氧化环糊精共聚物，其中包含未氧化和/或氧化的环糊精基团集成到聚合物骨架中。本发明还描述了制备这种共聚物的方法。本发明的线性环糊精共聚物和线性氧化环糊精共聚物可用作各种治疗剂的输送载体。
• [EN] COMBINATORIAL LIBRARIES<br/>[FR] BIBLIOTHÈQUES COMBINATOIRES
  申请人：DU PONT

  公开号：WO2015134256A1

  公开（公告）日：2015-09-11

  Synthetic mixtures comprising two or more synthetic oligoglucosamine based derivatives have been found to be useful in agricultural compositions for promoting seed germination. The disclosed synthetic mixtures may be applied to plant propagating materials, including seeds and other regenerable plant parts, including cuttings, bulbs, rhizomes and tubers. They may also be applied to foliage, or soil either prior to or following planting of plant propagating materials. Such applications may be made alone or in combination with fungicides, insecticides, nematicides and other agricultural agents used to improve plant growth and crop yield.

  含有两种或更多基于合成寡聚葡萄糖胺的衍生物的合成混合物已被发现在促进种子萌发的农业组合中具有用途。所披露的合成混合物可应用于植物繁殖材料，包括种子和其他可再生植物部分，包括插枝、鳞茎、根茎和块茎。它们也可以应用于叶片或土壤，无论是在种植植物繁殖材料之前还是之后。这些应用可以单独进行，也可以与杀菌剂、杀虫剂、杀线虫剂和其他用于改善植物生长和作物产量的农业剂一起使用。
• Compositions containing inclusion complexes
  申请人：California Institute of Technology and Insert Therapeutics, Inc

  公开号：US20030008818A1

  公开（公告）日：2003-01-09

  The invention provides a composition containing particulate composite of a polymer and a therapeutic agent. The composition also contains a complexing agent. The polymer interacts with the complexing agent in a host-guest or a guest-host interaction to form an inclusion complex. A therapeutic composition of the invention may be used to deliver the therapeutic agent and to treat various disorders. Both the polymer of the particulate composite and the complexing agent may be used to introduce functionality into the therapeutic composition. The invention also relates to a method of preparing a composition. The method combines a therapeutic agent, a polymer having host or guest functionality, and a complexing agent having guest or host functionality to form the therapeutic composition. The complexing agent forms an inclusion complex with the polymer. The invention also relates to a method of delivering a therapeutic agent. According to the method, a therapeutically effective amount of a therapeutic composition of the invention is administered to a mammal (e.g. person or animal) in recognized need of the therapeutic. Also disclosed are compounds having the formula: 1

  本发明提供了一种含有聚合物和治疗剂的颗粒复合物的组合物。该组合物还包含一种络合剂。聚合物与络合剂通过主-客体或客-主体相互作用形成包含物复合物。本发明的治疗组合物可用于输送治疗剂并治疗各种疾病。颗粒复合物的聚合物和络合剂均可用于向治疗组合物引入功能。本发明还涉及一种制备组合物的方法。该方法将治疗剂、具有主或客体功能的聚合物和具有客体或主体功能的络合剂结合以形成治疗组合物。络合剂与聚合物形成包含物复合物。本发明还涉及一种输送治疗剂的方法。根据该方法，将本发明的治疗组合物的治疗有效量用于需要治疗的哺乳动物（例如人或动物）。还公开了具有式1的化合物：