2,2,2-三氟-乙酸 11-巯基十一烷基酯 | 138524-05-7

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 中文名称: 2,2,2-三氟-乙酸 11-巯基十一烷基酯
• 中文别名: 11-巯基十一烷基三氟乙酸盐；2,2,2-三氟-乙酸11-巯基十一烷基酯
• 英文名称: 11-sulfanylundecanyltrifluoroethanoate
• 英文别名: 11-mercaptoundecyl trifluoroacetate；11-sulfanylundecyl 2,2,2-trifluoroacetate
• CAS: 138524-05-7
• 化学式: C₁₃H₂₃F₃O₂S
• 分子量: 300.386
• InChiKey: YOZNBMSWVPXLKM-UHFFFAOYSA-N

物化性质

• 熔点：
  50-51 °C
• 密度：
  1.059 g/mL at 25 °C
• 闪点：
  110 °C

计算性质

• 辛醇/水分配系数(LogP)：
  5.7
• 重原子数：
  19
• 可旋转键数：
  12
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.92
• 拓扑面积：
  27.3
• 氢给体数：
  1
• 氢受体数：
  6

安全信息

• WGK Germany：
  3

SDS

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SECTION 1: Identification of the substance/mixture and of the company/undertaking
Product identifiers
Product name : 11-Mercaptoundecyl trifluoroacetate
REACH No. : A registration number is not available for this substance as the substance
or its uses are exempted from registration, the annual tonnage does not
require a registration or the registration is envisaged for a later
registration deadline.
CAS-No. : 138524-05-7
Relevant identified uses of the substance or mixture and uses advised against
Identified uses : Laboratory chemicals, Manufacture of substances

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SECTION 2: Hazards identification
Classification of the substance or mixture
Classification according to Regulation (EC) No 1272/2008
Chronic aquatic toxicity (Category 4), H413
For the full text of the H-Statements mentioned in this Section, see Section 16.
This substance is not classified as dangerous according to Directive 67/548/EEC.
Label elements
Labelling according Regulation (EC) No 1272/2008
Pictogram none
Signal word none
Hazard statement(s)
H413 May cause long lasting harmful effects to aquatic life.
Precautionary statement(s) none
Supplemental Hazard none
Statements
Other hazards
Stench.

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SECTION 3: Composition/information on ingredients
Substances
Formula : C13H23F3O2S
Molecular Weight : 300,38 g/mol
CAS-No. : 138524-05-7
No components need to be disclosed according to the applicable regulations.
For the full text of the H-Statements and R-Phrases mentioned in this Section, see Section 16

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SECTION 4: First aid measures
Description of first aid measures
General advice
Consult a physician. Show this safety data sheet to the doctor in attendance.
If inhaled
If breathed in, move person into fresh air. If not breathing, give artificial respiration. Consult a physician.
In case of skin contact
Wash off with soap and plenty of water. Consult a physician.
In case of eye contact
Flush eyes with water as a precaution.
If swallowed
Never give anything by mouth to an unconscious person. Rinse mouth with water. Consult a physician.
Most important symptoms and effects, both acute and delayed
The most important known symptoms and effects are described in the labelling (see section 2.2) and/or in
section 11
Indication of any immediate medical attention and special treatment needed
no data available

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SECTION 5: Firefighting measures
Extinguishing media
Suitable extinguishing media
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
Special hazards arising from the substance or mixture
Carbon oxides, Sulphur oxides, Hydrogen fluoride
Advice for firefighters
Wear self contained breathing apparatus for fire fighting if necessary.
Further information
no data available

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SECTION 6: Accidental release measures
Personal precautions, protective equipment and emergency procedures
Avoid breathing vapours, mist or gas. Ensure adequate ventilation.
For personal protection see section 8.
Environmental precautions
Prevent further leakage or spillage if safe to do so. Do not let product enter drains. Discharge into the
environment must be avoided.
Methods and materials for containment and cleaning up
Keep in suitable, closed containers for disposal.
Reference to other sections
For disposal see section 13.

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SECTION 7: Handling and storage
Precautions for safe handling
Normal measures for preventive fire protection.
For precautions see section 2.2.
Conditions for safe storage, including any incompatibilities
Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Containers which are
opened must be carefully resealed and kept upright to prevent leakage.
Recommended storage temperature: 2 - 8 °C
Handle and store under inert gas.
Specific end use(s)
A part from the uses mentioned in section 1.2 no other specific uses are stipulated

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SECTION 8: Exposure controls/personal protection
Control parameters
Components with workplace control parameters
Exposure controls
Appropriate engineering controls
Handle in accordance with good industrial hygiene and safety practice. Wash hands before breaks and
at the end of workday.
Personal protective equipment
Eye/face protection
Use equipment for eye protection tested and approved under appropriate government standards
such as NIOSH (US) or EN 166(EU).
Skin protection
Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique
(without touching glove's outer surface) to avoid skin contact with this product. Dispose of
contaminated gloves after use in accordance with applicable laws and good laboratory practices.
Wash and dry hands.
The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC and
the standard EN 374 derived from it.
Body Protection
impervious clothing, The type of protective equipment must be selected according to the
concentration and amount of the dangerous substance at the specific workplace.
Respiratory protection
Respiratory protection not required. For nuisance exposures use type OV/AG (US) or type ABEK
(EU EN 14387) respirator cartridges. Use respirators and components tested and approved under
appropriate government standards such as NIOSH (US) or CEN (EU).
Control of environmental exposure
Prevent further leakage or spillage if safe to do so. Do not let product enter drains. Discharge into
the environment must be avoided.

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SECTION 9: Physical and chemical properties
Information on basic physical and chemical properties
a) Appearance Form: liquid
Colour: colourless
b) Odour no data available
c) Odour Threshold no data available
d) pH no data available
e) Melting point/freezing Melting point/range: 50 - 51 °C
point
f) Initial boiling point and no data available
boiling range
g) Flash point > 110 °C - closed cup
h) Evapouration rate no data available
i) Flammability (solid, gas) no data available
j) Upper/lower no data available
flammability or
explosive limits
k) Vapour pressure no data available
l) Vapour density no data available
m) Relative density 1,059 g/cm3 at 25 °C
n) Water solubility no data available
o) Partition coefficient: n- log Pow: 4,96
octanol/water
p) Auto-ignition no data available
temperature
q) Decomposition no data available
temperature
r) Viscosity no data available
s) Explosive properties no data available
t) Oxidizing properties no data available
Other safety information
no data available

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SECTION 10: Stability and reactivity
Reactivity
no data available
Chemical stability
Stable under recommended storage conditions.
Possibility of hazardous reactions
no data available
Conditions to avoid
no data available
Incompatible materials
Strong oxidizing agents
Hazardous decomposition products
Other decomposition products - no data available
In the event of fire: see section 5

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SECTION 11: Toxicological information
Information on toxicological effects
Acute toxicity
no data available
Skin corrosion/irritation
no data available
Serious eye damage/eye irritation
no data available
Respiratory or skin sensitisation
no data available
Germ cell mutagenicity
no data available
Carcinogenicity
IARC: No component of this product present at levels greater than or equal to 0.1% is identified as
probable, possible or confirmed human carcinogen by IARC.
Reproductive toxicity
no data available
Specific target organ toxicity - single exposure
no data available
Specific target organ toxicity - repeated exposure
no data available
Aspiration hazard
no data available
Additional Information
RTECS: Not available
To the best of our knowledge, the chemical, physical, and toxicological properties have not been
thoroughly investigated.

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SECTION 12: Ecological information
Toxicity
no data available
Persistence and degradability
no data available
Bioaccumulative potential
no data available
Mobility in soil
no data available
Results of PBT and vPvB assessment
PBT/vPvB assessment not available as chemical safety assessment not required/not conducted
Other adverse effects
no data available

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SECTION 13: Disposal considerations
Waste treatment methods
Product
Offer surplus and non-recyclable solutions to a licensed disposal company. Contact a licensed
professional waste disposal service to dispose of this material.
Contaminated packaging
Dispose of as unused product.

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SECTION 14: Transport information
UN number
ADR/RID: - IMDG: - IATA: 3334
UN proper shipping name
ADR/RID: Not dangerous goods
IMDG: Not dangerous goods
IATA: Aviation regulated liquid, n.o.s. (11-Mercaptoundecyl trifluoroacetate)
Transport hazard class(es)
ADR/RID: - IMDG: - IATA: 9
Packaging group
ADR/RID: - IMDG: - IATA: III
Environmental hazards
ADR/RID: no IMDG Marine pollutant: no IATA: no
Special precautions for user
no data available

---

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SECTION 15 - REGULATORY INFORMATION
N/A

---

SECTION 16 - ADDITIONAL INFORMATION
N/A

反应信息

• 作为产物：
  描述：

  11-巯基-1-十一醇 、 三氟乙酸酐 以 正己烷 为溶剂， 反应 0.01h， 生成 2,2,2-三氟-乙酸 11-巯基十一烷基酯
  参考文献：
  名称：

  Laibinis, Paul E.; Whitesides, George M., Journal of the American Chemical Society, 1992, vol. 114, # 6, p. 1990 - 1995

  摘要：

  DOI：

文献信息

• PROCESS FOR PRODUCING LAYERED PRODUCT, LAYERED PRODUCT, PROCESS FOR PRODUCING LAYERED PRODUCT WITH DEVICE USING SAID LAYERED PRODUCT, AND LAYERED PRODUCT WITH DEVICE
  申请人：Toyobo Co., Ltd.

  公开号：EP2865523A1

  公开（公告）日：2015-04-29

  There is provided a polyimide layered product with a support which has a smooth surface to enable a sophisticated device to be formed thereon and in which the layered polyimide does not peel off even in a high-temperature process on device formation, and furthermore, the polyimide layered product can be peeled off easily from the support after the device is formed on the polyimide layered product. By preparing a polyimide film with a face at the support side and subjected to a surface treatment; subjecting at least one of a face of the support and the face of the polyimide film which are opposite to each other to a patterning treatment using a coupling agent to form a satisfactorily bondable part and an easily releasable part which differ in adhesion/peel strength; subsequently, superposing the support and the polyimide film to be subjected to a pressurizing/heating treatment and to be bonded to each other; subjecting the surface of the polyimide film to an organic alkali treatment; and then, applying a polyamic acid solution free from a slip agent ingredient, drying the coating film and imidizing the film, a layered product having a structure of at least three layers in which at least one layer contains a slip agent material and both surface layers have no slip agent material is produced.

  本发明提供了一种具有支撑面的聚酰亚胺分层产品，该支撑面表面光滑，可在其上形成精密装置，而且即使在装置形成的高温过程中，分层聚酰亚胺也不会剥落，此外，在聚酰亚胺分层产品上形成装置后，聚酰亚胺分层产品可以很容易地从支撑面上剥落。通过制备表面位于支撑面的聚酰亚胺薄膜并对其进行表面处理；使用偶联剂对支撑面和聚酰亚胺薄膜相对面中的至少一个面进行图案化处理，以形成粘合力/剥离强度不同的可粘合部分和易剥离部分；然后，将支撑面和聚酰亚胺薄膜叠加在一起，进行加压/加热处理并相互粘合；将聚酰亚胺薄膜的表面进行有机碱处理；然后，涂上不含防滑剂成分的聚酰胺酸溶液，干燥涂膜并使薄膜酰亚胺化，这样就制成了一种具有至少三层结构的分层产品，其中至少一层含有防滑剂材料，而两层表面均不含防滑剂材料。
• DISPERSION
  申请人：Asahi Kasei Kabushiki Kaisha

  公开号：EP3305853A1

  公开（公告）日：2018-04-11

  A dispersion which contains a dispersant and particles selected from among metal particles and metal oxide particles, and which is characterized in that: the dispersant has a chemical structure that is able to be bonded or adsorbed to the particles; and the dispersant contains a low-molecular-weight dispersant that has at least one peak within a molecular weight region of 31 or more but less than 1,000 in the molecular weight distribution curve in terms of polyethylene glycol as determined by gel permeation chromatography and a high-molecular-weight dispersant that has at least one peak within a molecular weight region of 1,000 or more but 40,000 or less in the above-described molecular weight distribution curve.

  一种分散剂，它含有一种分散剂和选自金属颗粒和金属氧化物颗粒的颗粒，其特征在于分散剂的化学结构能与颗粒结合或吸附；分散剂含有一种低分子量分散剂，该分散剂在凝胶渗透色谱法测定的聚乙二醇分子量分布曲线中，至少有一个峰值在 31 或以上但小于 1,000 的分子量区域内；还含有一种高分子量分散剂，该分散剂在上述分子量分布曲线中，至少有一个峰值在 1,000 或以上但小于 40,000 的分子量区域内。
• Bismuth-thiols as antiseptics for epithelial tissues, acute and chronic wounds, bacterial biofilms and other indications
  申请人：Microbion Corporation

  公开号：US10835510B2

  公开（公告）日：2020-11-17

  Compositions and methods, including novel homogeneous microparticulate suspensions, are described for treating acute wounds, chronic wounds and/or a wound or epithelial tissue surface that contains bacterial biofilm, including unexpected synergy between bismuth-thiol (BT) compounds and certain antibiotics, to provide topical formulations including antiseptic formulations, for management and promotion of wound healing and in particular infected wounds. Previously unpredicted antibacterial properties and anti-biofilm properties of disclosed BT compounds and BT compound-plus-antibiotic combinations are also described, including preferential efficacies of certain such compositions for treating gram-positive bacterial infections, and distinct preferential efficacies of certain such compositions for treating gram-negative bacterial infections.

  本文描述了用于治疗急性伤口、慢性伤口和/或含有细菌生物膜的伤口或上皮组织表面的组合物和方法，包括新型均匀微粒悬浮液，包括铋硫醇（BT）化合物与某些抗生素之间意想不到的协同作用，以提供局部制剂，包括防腐制剂，用于管理和促进伤口愈合，特别是感染伤口。此外，还描述了已公开的 BT 化合物和 BT 化合物加抗生素组合物以前未曾预料到的抗菌特性和抗生物膜特性，包括某些此类组合物治疗革兰氏阳性细菌感染的优先功效，以及某些此类组合物治疗革兰氏阴性细菌感染的独特优先功效。
• Bismuth-thiols as antiseptics for biomedical uses, including treatment of bacterial biofilms and other uses
  申请人：Microbion Corporation

  公开号：US10960012B2

  公开（公告）日：2021-03-30

  Compositions and methods, including novel homogeneous microparticulate suspensions, are described for treating natural surfaces that contain bacterial biofilm, including unexpected synergy or enhancing effects between bismuth-thiol (BT) compounds and certain antibiotics, to provide formulations including antiseptic formulations. Previously unpredicted antibacterial properties and anti-biofilm properties of disclosed BT compounds and BT compound-plus-antibiotic combinations are also described, including preferential efficacies of certain such compositions for treating certain gram-positive bacterial infections, and distinct preferential efficacies of certain such compositions for treating certain gram-negative bacterial infections.

  介绍了用于处理含有细菌生物膜的天然表面的组合物和方法，包括新型均质微粒悬浮剂，包括铋硫醇（BT）化合物和某些抗生素之间意想不到的协同作用或增强效果，以提供包括防腐制剂在内的配方。此外，还描述了所公开的 BT 化合物和 BT 化合物加抗生素组合物以前未曾预料到的抗菌特性和抗生物膜特性，包括某些此类组合物治疗某些革兰氏阳性细菌感染的优先功效，以及某些此类组合物治疗某些革兰氏阴性细菌感染的独特优先功效。
• Covalent treatment with thiols of keratin-containing materials
  申请人：Living Proof, Inc.

  公开号：US10993903B2

  公开（公告）日：2021-05-04

  Disclosed are methods of preparing thiol keratin-containing materials, comprising applying a mixture comprising one or more thiol compounds and a catalyst. Methods of preparing cross-linked keratin-containing materials by applying a mixture comprising one or more thiol compounds and an oxidizing agent are also disclosed. Methods of grafting monomeric and polymeric materials on keratin-containing materials to provide a covalent coating on keratin-containing materials are disclosed. A mixture comprising one or more thiol compounds is applied to the keratin-containing material sample. The keratin-containing material sample then comprises a plurality of free thiol groups. A monomer is optionally applied to the keratin-containing material sample to form a plurality of covalent bonds between the free thiol groups and the monomers. The disclosed grafting methods can be carried out with or without catalyst.

  本发明公开了制备含硫醇角蛋白材料的方法，包括使用由一种或多种硫醇化合物和催化剂组成的混合物。还公开了通过使用由一种或多种硫醇化合物和氧化剂组成的混合物制备交联含角蛋白材料的方法。公开了在含角蛋白材料上接枝单体和聚合物材料以在含角蛋白材料上提供共价涂层的方法。将包含一种或多种硫醇化合物的混合物涂抹在含角蛋白材料样品上。这样，含角蛋白材料样品就含有多个游离硫醇基团。可选择将单体应用于含角蛋白材料样品，以在游离硫醇基团和单体之间形成多个共价键。所公开的接枝方法可在使用或不使用催化剂的情况下进行。