2,3-二氯-4-溴吡啶 | 859851-02-8

• 分子结构分类: 有机化合物 - 有机氧化合物
• 中文名称: 2,3-二氯-4-溴吡啶
• 中文别名: 2,3-二氢噻吩并[3,4-b][1,4]二噁英e-5-甲腈
• 英文名称: 2,3-Dihydrothieno[3,4-b][1,4]dioxine-5-carbonitrile
• CAS: 859851-02-8
• 化学式: C₇H₅NO₂S
• mdl: MFCD08060540
• 分子量: 167.19
• InChiKey: HSQAPDOVCIFQCU-UHFFFAOYSA-N

物化性质

• 熔点：
  70 °C

计算性质

• 辛醇/水分配系数(LogP)：
  1.4
• 重原子数：
  11
• 可旋转键数：
  0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.285
• 拓扑面积：
  70.5
• 氢给体数：
  0
• 氢受体数：
  4

安全信息

• 危险性防范说明：
  P261,P280,P301+P312,P302+P352,P305+P351+P338
• 危险性描述：
  H302,H315,H319,H335

反应信息

• 作为产物：
  描述：

  sodium isocyanate 、 3,4-乙烯二氧噻吩 在 2-溴-2-甲基丙二酸二乙酯 、 二苯基硅烷 、 吡啶溴化氢盐 、 1-Isopropyl-2,2,3,4,4-pentamethylphosphetane 1-oxide 作用下， 以 甲苯 为溶剂， 以25 %的产率得到2,3-二氯-4-溴吡啶
  参考文献：
  名称：

  10.1002/anie.202409854

  摘要：

  An organophosphorus redox‐catalyzed method for the direct electrophilic cyanation of C(sp2)–H nucleophiles with sodium cyanate (NaOCN) is reported. The catalytic deoxyfunctionalization of the OCN– anion is enabled by the use of a small‐ring phosphacyclic (phosphetane) catalyst in combination with a terminal hydrosilane O‐atom acceptor and a malonate‐derived bromenium donor. In situ spectroscopy under single‐turnover conditions demonstrate that insoluble inorganic cyanate anion is activated by bromide displacement on a bromophosphonium catalytic intermediate to give a reactive N‐bound isocyanatophosphonium ion, which delivers electrophilic “CN+” equivalents to nucleophilic (hetero)arenes and alkenes with loss of a phosphine oxide. These results demonstrate the feasibility of deoxyfunctionalization of insoluble inorganic salts by PIII/PV=O catalyzed phase transfer activation.

  DOI：

  10.1002/anie.202409854

文献信息

• FLUORESCENT DIKETOPYRROLOPYRROLES
  申请人：BASF SE

  公开号：EP1611207B1

  公开（公告）日：2016-02-03
• Fluorescent diketopyrrolopyrroles
  申请人：Yamamoto Hiroshi

  公开号：US20070010672A1

  公开（公告）日：2007-01-11

  The present invention relates to fluorescent diketopyrrolopyrrole of the formula (I), a process for their preparation and their use for the preparation of inks, colorants, pigmented plastics for coatings, non-impact-printing material, color filters, cosmetics, polymeric ink particles, toners, as fluorescent tracers, in color changing media, in solid dye lasers and electroluminescent devices. A luminescent device comprising a composition according to the present invention is high in the efficiency of electrical energy utilisation and high in luminance.
• US7501076B2
  申请人：——

  公开号：US7501076B2

  公开（公告）日：2009-03-10
• US7906039B2
  申请人：——

  公开号：US7906039B2

  公开（公告）日：2011-03-15