2,5-二甲氧基苯乙胺 | 3600-86-0

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 中文名称: 2,5-二甲氧基苯乙胺
• 中文别名: 2,5-二甲氧基苯乙基胺；2,4-二甲氧基肉桂酸
• 英文名称: 2,5-dimethoxyphenethylamine
• 英文别名: 2-(2,5-dimethoxyphenyl)ethan-1-amine；2-(2,5-dimethoxy-phenyl)-ethylamine；2,5-dimethoxyphenylethylamine；2-(2,5-dimethoxyphenyl)ethanamine
• CAS: 3600-86-0
• 化学式: C₁₀H₁₅NO₂
• 分子量: 181.235
• InChiKey: WNCUVUUEJZEATP-UHFFFAOYSA-N

物化性质

• 稳定性/保质期：

  在常温常压下保持稳定

计算性质

• 辛醇/水分配系数(LogP)：
  1.3
• 重原子数：
  13
• 可旋转键数：
  4
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.4
• 拓扑面积：
  44.5
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  2,5-二甲氧基苯乙胺 在 溴 、 溶剂黄146 作用下， 生成 4-溴-2,5二甲氧基苯乙胺
  参考文献：
  名称：

  氘标记苯乙胺衍生物的合成

  摘要：

  一系列五种氘标记的苯乙胺衍生物的合成，4-溴-2,5-[2H6]-二甲氧基苯乙胺（2C-B），4-氯-2,5-[2H6]-二甲氧基苯乙胺（2C-C）， 2,5-[2H6]-二甲氧基-4-碘苯乙胺 (2C-I)、2,5-[2H6]-二甲氧基-4-乙基噻吩乙胺 (2C-T-2) 和 2,5-[2H6]-二甲氧基-描述了来自 1,4-[2H6]-二甲氧基苯的 4-n-丙基噻吩乙胺 (2C-T-7)。同位素标记的化合物用作气相色谱-质谱 (GC-MS) 分析中的内标。版权所有 © 2006 John Wiley & Sons, Ltd.

  DOI：

  10.1002/jlcr.1139
• 作为产物：
  描述：

  3-(2,5-二甲氧苯基)丙酸 在 戊醇 、 硫酸 、 一水合肼 、 苯 作用下， 生成 2,5-二甲氧基苯乙胺
  参考文献：
  名称：

  Dynamic Rearrangement Within the Antheraea pernyi Silk Fibroin Gene Is Associated with Four Types of Repetitive Units

  摘要：

  We characterized a full-length gene encoding wild silkmoth Antheraea pernyi fibroin (Ap-fibroin) to clarify the conformation of repetitive sequences. The gene consisted of a first exon encoding 14 amino acid residues, a short intron (120 bp), and a long second exon encoding 2,625 amino acid residues. Three amino acids, alanine, glycine, and serine, amounted to 81% of the Ap-fibroin sequence. The Ap-fibroin, except for 155 residues of the amino terminus, was composed of 80 tandemly arranged polyalanine-containing units (motifs). A motif was a doublet of a polyalanine block (PAB) and a nonpolyalanine block (NPAB). Seventy-eight of the 80 motifs were classified into four types based on differences in the NPAB sequences. Although respective motifs were significantly conserved, many rearrangements were observed within the second exon, i.e., the triplication of a 558-bp-long sequence and other duplication events of shorter sequences. Chi-like sequences, GCTGGAG, might contribute to the rearrangement within the gene as described in human minisatellite loci, because they were found at specific sites of NPAB-encoding sequences in three of four types of motifs. The present results support the idea that the Ap-fibroin gene is unstable like minisatellite sequences and that the evolution of this gene is strongly associated with its instability.