2-(2,4-二溴苯氧基)乙酰氯 | 16738-07-1

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯酚醚
• 中文名称: 2-(2,4-二溴苯氧基)乙酰氯
• 英文名称: 2,4-dibromophenoxyacetyl chloride
• 英文别名: (2,4-Dibromophenoxy)acetyl chloride；2-(2,4-dibromophenoxy)acetyl chloride
• CAS: 16738-07-1
• 化学式: C₈H₅Br₂ClO₂
• mdl: MFCD11107988
• 分子量: 328.387
• InChiKey: ABJOJUXBOIRTBS-UHFFFAOYSA-N

物化性质

• 沸点：
  331.5±27.0 °C(Predicted)
• 密度：
  1.922±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  3.7
• 重原子数：
  13
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.12
• 拓扑面积：
  26.3
• 氢给体数：
  0
• 氢受体数：
  2

安全信息

• 危险等级：
  IRRITANT
• 海关编码：
  2918990090

反应信息

• 作为反应物：
  描述：

  吩噻嗪 、 2-(2,4-二溴苯氧基)乙酰氯 在 sodium hydroxide 作用下， 以 甲醇 、 乙醚 、 乙酸乙酯 为溶剂， 以70%的产率得到10H-Phenothiazine, 10-((2,4-dibromophenoxy)acetyl)-
  参考文献：
  名称：

  Chaurasia; Srivastava, Journal of the Indian Chemical Society, 1991, vol. 68, # 2, p. 106 - 107

  摘要：

  DOI：
• 作为产物：
  描述：

  sodium 2,4-dibromophenolate 在 氯化亚砜 作用下， 以 乙酸乙酯 为溶剂， 反应 8.0h， 生成 2-(2,4-二溴苯氧基)乙酰氯
  参考文献：
  名称：

  Chaurasia, Sunita; Srivastava, Savitri D., Journal of the Indian Chemical Society, 1992, vol. 69, # 1, p. 45 - 46

  摘要：

  DOI：

文献信息

• Srivastava; Purohit; Srivastava, Journal of the Indian Chemical Society, 1991, vol. 68, # 6, p. 358 - 359
  作者：Srivastava、Purohit、Srivastava、Jain、Khubchandani

  DOI：——

  日期：——
• Studies of <i>O</i>,<i>O</i>-Dimethyl α-(2,4-Dichlorophenoxyacetoxy)ethylphosphonate (HW02) as a New Herbicide. 1. Synthesis and Herbicidal Activity of HW02 and Analogues as Novel Inhibitors of Pyruvate Dehydrogenase Complex
  作者：Hong-Wu He、Jun-Lin Yuan、Hao Peng、Ting Chen、Ping Shen、Shu-Qing Wan、Yanjun Li、Hong-Liang Tan、Ya-Hui He、Jun-Bo He、Yan Li

  DOI：10.1021/jf104247w

  日期：2011.5.11

  On the basis of the previous work for optimization of O,O-diethyl alpha-(substituted phenoxyacetoxy)alkylphosphonates, further extensive synthetic modifications were made to the substituents in alkylphosphonate and phenoxy moieties of the title compounds. New O,O-dimethyl alpha-(substituted phenoxyacetoxy)alkylphosphonates were synthesized as potential inhibitors of pyruvate dehydorogenase complex (PDHc). Their herbicidal activity and efficacy in vitro against PDHc were examined. Some of these compounds exhibited significant herbicidal activity and were demonstrated to be effective inhibitors of PDHc from three different plants. The structure-activity relationships of these compounds including previously reported analogous compounds were studied by examining their herbicidal activities. Both inhibitory potency against PDHc and herbicidal activity of title compounds could be increased greatly by optimizing substituent groups of the title compounds. O,O-Dimethyl alpha-(2,4-dichlorophenoxyacetoxy)ethylphosphonate (I-5), which acted as a competitive inhibitor of PDHc with much higher inhibitory potency against PDHc from Pisum sativum and Phaseolus radiatus than from Oryza sativa , was found to be the most effective compound against broadleaf weeds and showed potential utility as herbicide.
• Purohit; Srivastava, Journal of the Indian Chemical Society, 1991, vol. 68, # 3, p. 163 - 165
  作者：Purohit、Srivastava

  DOI：——

  日期：——
• Bhatt, P.; Srivastava, S. D.; Mehta, P., Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 1998, vol. 37, # 5, p. 514 - 516
  作者：Bhatt, P.、Srivastava, S. D.、Mehta, P.

  DOI：——

  日期：——
• Chaurasia, Sunita; Srivastava, Savitri D., Journal of the Indian Chemical Society, 1992, vol. 69, # 1, p. 45 - 46
  作者：Chaurasia, Sunita、Srivastava, Savitri D.

  DOI：——

  日期：——