N-[(2S,3R,4S)-2,3,4,5-tetrahydroxypentyl]formamide

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: N-[(2S,3R,4S)-2,3,4,5-tetrahydroxypentyl]formamide
• 化学式: C₆H₁₃NO₅
• 分子量: 179.17
• InChiKey: TTZBGONHUFMKGZ-HCWXCVPCSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -3
• 重原子数：
  12
• 可旋转键数：
  5
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.83
• 拓扑面积：
  110
• 氢给体数：
  5
• 氢受体数：
  5

文献信息

• Process for the preparation of 2-hydroxymethyl-pyrolidine 3, 4-diols
  申请人：——

  公开号：US20040185539A1

  公开（公告）日：2004-09-23

  A process for the preparation of 2-hydroxymethyl-pyrrolidine-3,4-diols of the formulae comprising the steps of a) biooxidation of N-protected aminotetraols of the formula b) deprotection of the corresponding N-protected 5-amino-5-deoxy-pentulose c) hydrogenation of the corresponding 5-amino-5-deoxy-pentulose. 1

  一种制备式子中2-羟甲基吡咯烷-3,4-二醇的过程，包括以下步骤：a）对式子b中的N-保护氨基四醇进行生物氧化；b）对应的N-保护5-氨基-5-脱氧戊糖去保护；c）对应的5-氨基-5-脱氧戊糖进行氢化。1
• Process for the preparation of 2-hydroxymethyl-pyrrolidine-3,4-diols
  申请人：KAMPFEN Ulrich

  公开号：US20090155862A1

  公开（公告）日：2009-06-18

  A process for the preparation of 2-hydroxymethyl-pyrrolidine-3,4-diols of the formulae: including the steps of: a) bioxidation of N-protected aminotetraols of the formula: b) deprotection of the corresponding 5-amino-5-deoxy-pentulose of the formula: and c) hydrogenation of the corresponding 5-amino-5-deoxy-pentulose of the formula:

  一种制备式为2-羟甲基吡咯烷-3,4-二醇的过程，包括以下步骤： a) 对式为N-保护氨基四醇的生物氧化： b) 对应的5-氨基-5-脱氧戊糖的脱保护： c) 对应的5-氨基-5-脱氧戊糖的氢化：
• PROCESS FOR THE PREPARATION OF 2-HYDROXYMETHYL-PYROLIDINE-3,4-DIOLS
  申请人：Lonza AG

  公开号：EP1379676A2

  公开（公告）日：2004-01-14
• [EN] PROCESS FOR THE PREPARATION OF 2-HYDROXYMETHYL-PYROLIDINE-3,4-DIOLS<br/>[FR] PROCEDE DE PREPARATION DE 2-HYDROXYMETHYL-PYROLIDINE-3,4-DIOLS
  申请人：LONZA AG

  公开号：WO2002074737A2

  公开（公告）日：2002-09-26

  A process for the preparation of 2-hydroxymethyl-pyrrolidine-3,4-diols of the formulae comprising the steps of a) biooxidation of N-protected aminotetraols of the formula b) deprotection of the corresponding N-protected 5-amino-5-deoxy-pentulose c) hydrogenation of the corresponding 5-amino-5-deoxy-pentulose.