1,1'-ethanediyl-bis-cyclopentanol | 60858-65-3

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 1,1'-ethanediyl-bis-cyclopentanol
• 英文别名: 1,1'-Aethandiyl-bis-cyclopentanol；1.2-Bis-(1-hydroxy-cyclopentyl)-aethan；Cambridge id 5100819；1-[2-(1-hydroxycyclopentyl)ethyl]cyclopentan-1-ol
• CAS: 60858-65-3
• 化学式: C₁₂H₂₂O₂
• 分子量: 198.305
• InChiKey: PTOYVDSVHKURGZ-UHFFFAOYSA-N

物化性质

• 熔点：
  131.2-131.4 °C
• 沸点：
  85-89 °C(Press: 0.5 Torr)
• 密度：
  1.090±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  1.7
• 重原子数：
  14
• 可旋转键数：
  3
• 环数：
  2.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  40.5
• 氢给体数：
  2
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  cis-1.2-bis-(1-hydroxy-cyclopentyl)-ethylene 在 乙醇 、 铂 作用下， 生成 1,1'-ethanediyl-bis-cyclopentanol
  参考文献：
  名称：

  Salkind; Gwerdziteli, Zhurnal Obshchei Khimii, 1939, vol. 9, p. 855,861

  摘要：

  DOI：

文献信息

• PREPARATION AND DEHYDRATION OF DI-(1-HYDROXYCYCLOALKYL)-ALKANES
  作者：A. S. Bailey、D. G. M. Diaper、M. V. H. Schwemin

  DOI：10.1139/v61-142

  日期：1961.5.1

  not available

  不可用
• The Synthesis of Cyclic Alcohols and Olefins by the Interaction of Dimagnesium Halides and Esters
  作者：Costin D. Nenitzescu、Ileana Necsoiu

  DOI：10.1021/ja01164a046

  日期：1950.8
• Synthesis and Applications of Tetrahydrofuran-Stable Substituted (3-Lithioxyalkyl)- and (4-Lithioxyalkyl)lithiums, Modified with Magnesium 2-Ethoxyethoxide
  作者：Ioannis D. Kostas、Constantinos G. Screttas

  DOI：10.1021/jo9703010

  日期：1997.8.1

  Substituted hydroxyalkyl phenyl sulfides 3 have been synthesized from the corresponding allylic or homoallylic alcohols 2. Regiospecific cleavage of the C-SPh bond of the sulfides 3 by lithium dispersion in tetrahydrofuran (THF) led to the synthesis of substituted (3-lithioxyalkyl)- and (4-lithioxyalkyl)lithiums 4, most of which share the omega carbon with a carbocyclic ring. The organolithiums were modified with magnesium 2-ethoxyethoxide in order to suppress their reactivity toward THF cleavage, thus offering the advantage of preparing storable ethereal solutions of certain types of (lithioxyalkyl)lithiums. This strategy appears to be of rather broad scope. The functionalized organolithiums prepared in this way react normally with electrophilic reagents with yields in the range 35-55%. Thus, carboxylations of 4 yielded lactones 5, some of which are natural products, while reactions of 4 with benzophenone and cyclic ketones yielded 1,4- and 1,5-diols 6 and 7, respectively.
• TiCl4/Mg/BrCH2CH2Br Reagent System: A 1,2-Diorganometallic Equivalent
  作者：S.Achyutha Rao、M. Periasamy

  DOI：10.1016/s0040-4039(00)80359-7

  日期：——
• Salkind; Gwerdziteli, Zhurnal Obshchei Khimii, 1939, vol. 9, p. 855,861
  作者：Salkind、Gwerdziteli

  DOI：——

  日期：——