烟酰胺氢碘 | 3726-23-6

• 物质功能分类: 医药中间体 - 杂环化合物 - 吡啶类化合物
• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡啶及其衍生物
• 中文名称: 烟酰胺氢碘
• 英文名称: nicotinic acid amide; hydriodide
• 英文别名: Nicotinsaeure-amid; Hydrojodid；3-pyridinecarboxamide, monohydriodide；nicotinamide monohydroiodide；pyridin-1-ium-3-carboxamide;iodide
• CAS: 3726-23-6
• 化学式: C₆H₇N₂O*I
• 分子量: 250.039
• InChiKey: ITWGXEQHZZFQES-UHFFFAOYSA-N

物化性质

• 熔点：
  223-226 °C

计算性质

• 辛醇/水分配系数(LogP)：
  0.8
• 重原子数：
  10
• 可旋转键数：
  1
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  56
• 氢给体数：
  2
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  sodium hexacarbonylvanadate 、 烟酰胺氢碘 在 HCl 作用下， 以 水 为溶剂， 以45%的产率得到{H-Nic}hexacarbonylvanadate
  参考文献：
  名称：

  5族金属六羰基衍生物的合成和电子转移过程。四羰基[1,2-双（二苯基膦基）乙烷]碘钽的晶体和分子结构

  摘要：

  DOI：

  10.1021/om00095a011

文献信息

• Novel complexes of fatty acid esters of polyhydroxylalkanes and pyridine carboxy derivates
  申请人：Astion Dermatology A/S

  公开号：EP1640011A1

  公开（公告）日：2006-03-29

  The present invention relates to novel combinations of fatty acid derivatives and pyridine carboxy derivatives, including fatty acid esters with glycerol and 3-carboxy pyridine derivatives such as niacinamide. Such combinations have surprisingly shown antiviral and anti-microbial activity and the use for the treatment of inflammatory conditions and infections is disclosed herein.

  本发明涉及脂肪酸衍生物和吡啶羧基衍生物的新型组合，包括含甘油的脂肪酸酯和烟酰胺等 3-羧基吡啶衍生物。这些组合物令人惊奇地显示出抗病毒和抗微生物活性，本发明公开了其在治疗炎症和感染方面的用途。
• Pyridine carboxy derivatives and an aminosugar
  申请人：Astion Deveopment A/S

  公开号：US20030105034A1

  公开（公告）日：2003-06-05

  The present invention relates to chemical complexes consisting of a pyridine carboxy derivative and an aminosugar as well as pharmaceutical compositions and dietary supplements comprising such complexes. The invention further relates to the use of such compositions or complexes for the preparation of a medicament or a dietary supplement in the suppression of hypersensitivity and inflammatory reactions such as dermatological disorders or to a method of treating such disorders by administering such compositions and complexes to a mammal, such as a human.

  本发明涉及由吡啶羧基衍生物和氨基糖组成的化学复合物，以及包含此类复合物的药物组合物和膳食补充剂。本发明还涉及使用此类组合物或复合物制备药物或膳食补充剂，以抑制超敏反应和炎症反应，如皮肤病，或通过向哺乳动物（如人类）施用此类组合物和复合物来治疗此类疾病的方法。
• Novel complexes of fatty acid esters of polyhydroxyalkanes and pyridine carboxy derivatives
  申请人：Weidner Sloth Morten

  公开号：US20060069131A1

  公开（公告）日：2006-03-30

  The present invention relates to novel combinations of fatty acid derivatives and pyridine carboxy derivatives, including fatty acid esters with glycerol and 3-carboxy pyridine derivatives such as niacinamide. Such combinations have surprisingly shown antiviral and anti-microbial activity and the use for the treatment of inflammatory conditions and infections is disclosed herein.

  本发明涉及脂肪酸衍生物和吡啶羧基衍生物的新型组合，包括含甘油的脂肪酸酯和烟酰胺等 3-羧基吡啶衍生物。这些组合物令人惊奇地显示出抗病毒和抗微生物活性，本发明公开了其在治疗炎症和感染方面的用途。
• NOVEL COMPLEXES OF FATTY ACID ESTERS OF POLYHYDROXYALKANES AND NIACINAMIDE
  申请人：Astion Dermatology A/S

  公开号：EP1560589B1

  公开（公告）日：2006-10-04
• NOVEL COMPLEXES OF FATTY ACID ESTERS OF POLYHYDROXYALKANES AND PYRIDINE CARBOXY DERIVATIVES
  申请人：Astion Dermatology A/S

  公开号：EP1560589A1

  公开（公告）日：2005-08-10