4-methylstyryltrimethylsilane | 132536-24-4

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 4-methylstyryltrimethylsilane
• 英文别名: Trimethyl-[2-(4-methylphenyl)ethenyl]silane
• CAS: 132536-24-4
• 化学式: C₁₂H₁₈Si
• 分子量: 190.36
• InChiKey: SADUZZBELASGCA-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.89
• 重原子数：
  13
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.33
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  0

反应信息

• 作为产物：
  描述：

  二(三甲基硅基)氯甲烷 、 对甲基苯甲醛 在 仲丁基锂 作用下， 以 四氢呋喃 、 环己烷 为溶剂， 反应 0.67h， 以87%的产率得到4-methylstyryltrimethylsilane
  参考文献：
  名称：

  采用新型的金属化-彼德森序列，可以快速有效地从醛类转化为乙烯基硅烷。

  摘要：

  双（三甲基甲硅烷基）氯甲烷与s-BuLi进行快速选择性的金属化反应，生成亲核性双（三甲基甲硅烷基）甲基阴离子，并提供了从芳族，脂肪族和乙烯基醛类直接进入乙烯基硅烷的一般方法。

  DOI：

  10.1039/b716897g

文献信息

• Supported palladium nanoparticles as heterogeneous ligand-free catalysts for the Hiyama C–C coupling of vinylsilanes and halobenzenes leading to styrenes
  作者：Abdessamad Grirrane、Hermenegildo Garcia、Avelino Corma

  DOI：10.1016/j.jcat.2013.02.019

  日期：2013.6

  The Hiyama C-C coupling reaction of a wide range of aryl iodides and vinylsilanes has been performed using ligand-free solid catalysts based on supported palladium nanoparticles. Among the supports tested (Mg, TiO2, CeO2 and active carbon), the most active catalysts were those in which palladium is supported on MgO and TiO2. Analogous Pt and Au materials were inefficient to promote this reaction. Leaching tests suggest that there is some contribution of dissolved Pd since Pd in solution has been detected and the scavenging test decreases the initial reaction rate. Although the solid Pd catalysts can be reused, it was, however, observed that they undergo a certain deactivation upon use that can be attributed to several factors including the presence of inorganic compounds on the catalyst, Pd leaching or agglomeration of Pd NPs. (c) 2013 Elsevier Inc. All rights reserved.
• Taylor, Roger, Journal of the Chemical Society. Perkin transactions II, 1991, # 11, p. 1703 - 1706
  作者：Taylor, Roger

  DOI：——

  日期：——
• Rapid and efficient entry to vinyl silanes from aldehydes employing a novel metalation–Peterson sequence
  作者：James McNulty、Priyabrata Das

  DOI：10.1039/b716897g

  日期：——

  Bis(trimethylsilyl)chloromethane undergoes a rapid and selective metalation with s-BuLi, yielding the nucleophilic bis(trimethylsilyl)methyl anion and providing a straightforward general entry to vinyl silanes from aromatic, aliphatic and vinyl aldehydes.

  双（三甲基甲硅烷基）氯甲烷与s-BuLi进行快速选择性的金属化反应，生成亲核性双（三甲基甲硅烷基）甲基阴离子，并提供了从芳族，脂肪族和乙烯基醛类直接进入乙烯基硅烷的一般方法。