1,2-Bis<(2-bromophenyl)oxy>ethane | 131354-70-6

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯酚醚
• 英文名称: 1,2-Bis<(2-bromophenyl)oxy>ethane
• 英文别名: 1,2-bis(2-bromophenoxy)ethane；1-bromo-2-[2-(2-bromophenoxy)ethoxy]benzene；1,2-Bis-(2-brom-phenoxy)-aethan；Aethylenglykol-bis-(2-brom-phenyl)-aether
• CAS: 131354-70-6
• 化学式: C₁₄H₁₂Br₂O₂
• 分子量: 372.056
• InChiKey: QVONITRHNNXBDK-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.9
• 重原子数：
  18
• 可旋转键数：
  5
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.14
• 拓扑面积：
  18.5
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  1,2-Bis<(2-bromophenyl)oxy>ethane 在 四(三苯基膦)钯 、 正丁基锂 、 5%-palladium/activated carbon 、 氢气 、 potassium carbonate 、 溶剂黄146 作用下， 以 乙二醇二甲醚 、 乙醚 、 乙醇 、 正己烷 、 水 、 乙酸乙酯 为溶剂， 反应 16.0h， 生成 2-tert-butyl-6-[2-[2-[2-(3-tert-butyl-2-hydroxy-5-methylphenyl)phenoxy]ethoxy]phenyl]-4-methylphenol
  参考文献：
  名称：

  Zr / Hf双酚（酚盐醚）预催化剂的形成和活化

  摘要：

  双（酚盐醚）（“ O4”）配体的Zr和Hf配合物具有高温下丙烯聚合的高活性，立体选择性和分子量能力。在这里，我们报告了简化的配体合成和O4配体的几个新实例。由L H 2和MR 4形成的预催化剂L MR 2（M = Zr，Hf; R = Bn，Me）在某些情况下伴随着二聚物（µ-L）2 [MR 2 ]的形成。2，并且已经确定了两个这样的二聚体的X射线结构。用[Ph 3 C] + [B（C）处理L MMe 26 F 5）4 ] –产生相当干净的阳离子物种L MMe +，通过1 H NMR研究。二维ROESY数据尤其表明，对于“较小”的O4配体，L MMe +阳离子可逆地从活性形式（fac / fac）重新排列为大概无活性的fac / mer或mer / mer形式；更大的取代基似乎抑制了这种重排。讨论了聚合催化的意义。

  DOI：

  10.1002/ejic.201900716
• 作为产物：
  描述：

  1-(2-溴乙氧基)-2-溴苯 以20%的产率得到
  参考文献：
  名称：

  Romanelli Gustavo P., Autino Juan C., Vitale Arturo A., Pomilio Alicia B., J. Chem. Res. Synop, (1993) N 9, S 386-387

  摘要：

  DOI：

文献信息

• Aryl tert-butyl sulfoxide-promoted highly enantioselective addition of allyltrichlorosilane to aldehydes
  作者：Peng Wang、Junmin Chen、Linfeng Cun、Jingen Deng、Jin Zhu、Jian Liao

  DOI：10.1039/b909850j

  日期：——

  A series of enantiomerically pure mono- and bis-aryl tert-butyl sulfoxides were synthesised to promote the enantioselective allylation of aldehydes with allyltrichlorosilane. Moderate to good yields and modest to high enantioselectivities were achieved. The absence of nonlinear effect, spacer effect, promoter loading and concentration effect indicate that only one molecule of aryl tert-butyl sulfoxide is involved in the stereodetermining step.

  一系列手性纯的单和双芳基叔丁基亚砜被合成出来，以促进醛与烯丙基三氯硅烷的非对映选择性烯丙基化反应。实现了中等至良好的产率和适中至高的非对映选择性。非线性效应、间隔效应、促进剂加载和浓度效应的缺失表明，在决定立体化学的步骤中，只有一分子芳基叔丁基亚砜参与其中。
• [EN] METHODS FOR PREPARING BRIDGED BI-AROMATIC LIGANDS<br/>[FR] PROCÉDÉS DE PRÉPARATION DE LIGANDS BI-AROMATIQUES PONTÉS
  申请人：UNIVATION TECH LLC

  公开号：WO2016172114A1

  公开（公告）日：2016-10-27

  New methods of preparing bridged bi-aromatic ligands are disclosed. The methods employ direct di-ortho-lithiation of aromatic rings of bridged protected bi-aromatic diphenols. The ligands may be used to prepare transition metal compounds useful as catalysts in olefin polymerization.

  公开了制备桥式双芳香配体的新方法。该方法采用桥式保护双芳香二酚的芳香环的直接二正石墨化。该配体可用于制备过渡金属化合物，用作烯烃聚合催化剂。
• Methods for preparing bridged bi-aromatic ligands
  申请人：Univation Technologies, LLC

  公开号：US10239809B2

  公开（公告）日：2019-03-26

  New methods of preparing bridged bi-aromatic ligands are disclosed. The methods employ direct di-ortho-lithiation of aromatic rings of bridged protected bi-aromatic diphenols. The ligands may be used to prepare transition metal compounds useful as catalysts in olefin polymerization.

  本发明公开了制备桥接双芳香族配体的新方法。这些方法采用桥接的受保护双芳香族二酚的芳香环的直接二正硫化反应。这些配体可用于制备过渡金属化合物，作为烯烃聚合的催化剂。
• Macroring-neutral molecule complexation. Synthesis of biconcave pyridino hosts, complex formation, and x-ray crystal structures of two inclusion compounds
  作者：Edwin Weber、Hans Juergen Koehler、Hans Reuter

  DOI：10.1021/jo00003a055

  日期：1991.2

  A series of pyridino macrocycles 1-3(a-e) incorporating rigid bi- and triaryl ether segments in different ring positions have been synthesized. The effect of incorporation of these building blocks into a given macroring framework on the host properties for uncharged-molecule inclusion has been studied. Symmetric 21-membered macrorings 1c, 1d, or 2c, 2d with tri-o-phenylene, tri-2,3-naphthylene, or mixed phenylene naphthylene ether units are efficient hosts in solid-state complexation of dipolar-aprotic and apolar guests such as nitro compounds and nitriles as well as DMF, DMSO, THF, dioxane, or benzene. X-ray analyses of the solid-state complexes of 1d with PhNO2 (1:1) and MeCN (1:1) have been studied. It is shown that the presence of the triaryl ether segment induces a biconcave nonequally sided host conformation suitable for guest inclusion. The packing characterizes the host-guest topologies of the two inclusion compounds to be of (H-bonded) cavitate-type for the MeCN case and of interstitial channel type for the PhNO2 case. A comparative discussion of the present and previous results support the interpretation of hemispherand preorganization for the new host structures.
• Stoermer; Goehl, Chemische Berichte, 1903, vol. 36, p. 2875 Anm. 2
  作者：Stoermer、Goehl

  DOI：——

  日期：——