[EN] NOVEL 2,3-BENZODIAZEPINE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME AS THE ACTIVE INGREDIENT<br/>[FR] NOUVEAUX DERIVES DE 2,3-BENZODIAZEPINE ET COMPOSITIONS PHARMACEUTIQUES CONTENANT LESDITS DERIVES COMME MATIERE ACTIVE
申请人:EGYT GYOGYSZERVEGYESZETI GYAR
公开号:WO2002050044A1
公开(公告)日:2002-06-27
The invention refers to novel 2,3-benzodiazepine derivatives of formula (I) and pharmaceutical compositions containing the same as the active ingredient. The novel compounds have antipasmodic, muscle relaxant and neuroprotective activities. In formula I; X represents a hydrogen atom, a chloro atom or a methoxy group; Y stands for a hydrogen atom or a halo atom; Z means a methyl group or a chloro atom; R is a C1-4 alkyl group or a group of the formula -NR1R2, wherein R?1 and R2¿ represent, independently, a hydrogen atom, a C¿1-4? alkyl group, a C1-4 alkoxy group or a C?3-6¿ cycloalkyl group.
Novel 2, 3 - benzodiazepine derivatives and pharmaceutical compositions containing the same as the active ingredient
申请人:——
公开号:US20040092510A1
公开(公告)日:2004-05-13
The invention refers to novel 2,3-benzodiazepine derivatives of formula (I) and pharmaceutical compositions containing the same as the active ingredient. The novel compounds antipasmodic, muscle relaxant and neuroprotective activities. In formula I; X represents a hydrogen atom, a chloro atom or a methoxy group; Y stands for a hydrogen atom or a halo atom; Z means a methyl group or a chloro atom; R is a C
1-4
alkyl group or a group of the formula —NR
1
R
2
, wherein R
1
and R
2
represent, independently, a hydrogen atom, a C
1-4
alkyl group, a C
1-4
alkoxy group or a C
3-6
cycloalkyl group.
1
NOVEL 2,3-BENZODIAZEPINE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME AS THE ACTIVE INGREDIENT
申请人:Egis Gyogyszergyar Rt.
公开号:EP1351942B1
公开(公告)日:2004-07-21
Methods and compositions for polypeptide engineering
申请人:Patten A. Phillip
公开号:US20070031878A1
公开(公告)日:2007-02-08
Methods are provided for the evolution of proteins of industrial and pharmaceutical interest, including methods for effecting recombination and selection. Compositions produced by these methods are also disclosed.
METHODS AND COMPOSITIONS FOR POLYPEPTIDE ENGINEERING
申请人:Patten Phillip A.
公开号:US20120015820A1
公开(公告)日:2012-01-19
Methods are provided for the evolution of proteins of industrial and pharmaceutical interest, including methods for effecting recombination and selection. Compositions produced by these methods are also disclosed.