5-(4-benzyloxyphenyl)pentanol | 142516-74-3

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: 5-(4-benzyloxyphenyl)pentanol
• 英文别名: 5-(4-phenylmethoxyphenyl)pentan-1-ol
• CAS: 142516-74-3
• 化学式: C₁₈H₂₂O₂
• 分子量: 270.371
• InChiKey: PBQVPVJEIXHPPZ-UHFFFAOYSA-N

物化性质

• 沸点：
  405.7±25.0 °C(Predicted)
• 密度：
  1.064±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  4.1
• 重原子数：
  20
• 可旋转键数：
  8
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.33
• 拓扑面积：
  29.5
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  5-(4-benzyloxyphenyl)pentanol 在 palladium on activated charcoal 吡啶 、 zinc diacetate 、 氢气 、 potassium carbonate 作用下， 以 氯仿 、 溶剂黄146 、 乙腈 为溶剂， 反应 42.0h， 生成 35,41,47,52-tetratert-butyl-17,62-dimethyl-3,31-dioxaundecacyclo[31.15.7.711,23.19,13.115,19.121,25.139,43.150,54.02,45.032,37.160,64]octahexaconta-1,9(67),10,12,15,17,19(66),21,23,25(58),32,34,36,39(57),40,42,45,47,50,52,54(56),60(68),61,63-tetracosaene-12,22,56,57,66,68-hexol
  参考文献：
  名称：

  Head-to-tail connected double calix[4]arenes

  摘要：

  New macrotricyclic compounds consisting of two calix[4]arene substructures connected by aliphatic chains of various length (three to five carbon atoms) between two opposite p-positions and two distal phenolic oxygens have been synthesized. Starting with p-tert-butyl-calix[4] arene, two O-protected phenolic units are attached via ether links in 1,3-position by reaction with the corresponding tosylates. After deprotection, the new calix[4]arene is formed by fragment condensation with 2,6-bisbromomethylated 4-alkylphenols. The structure of one example (8c) has been confirmed by single crystal X-ray analysis. Both calixarene parts assume the cone conformation, a molecule of acetonitrile being included in both cavities.

  DOI：

  10.1007/bf00807096
• 作为产物：
  描述：

  5-(4-羟基苯基)戊酸 在 sodium hydroxide 、 lithium aluminium tetrahydride 作用下， 以 乙醚 、 乙醇 为溶剂， 生成 5-(4-benzyloxyphenyl)pentanol
  参考文献：
  名称：

  Head-to-tail connected double calix[4]arenes

  摘要：

  New macrotricyclic compounds consisting of two calix[4]arene substructures connected by aliphatic chains of various length (three to five carbon atoms) between two opposite p-positions and two distal phenolic oxygens have been synthesized. Starting with p-tert-butyl-calix[4] arene, two O-protected phenolic units are attached via ether links in 1,3-position by reaction with the corresponding tosylates. After deprotection, the new calix[4]arene is formed by fragment condensation with 2,6-bisbromomethylated 4-alkylphenols. The structure of one example (8c) has been confirmed by single crystal X-ray analysis. Both calixarene parts assume the cone conformation, a molecule of acetonitrile being included in both cavities.

  DOI：

  10.1007/bf00807096

文献信息

• Optically active ester derivatives, preparation process thereof, liquid crystal materials and a light switching element
  申请人：SUMITOMO CHEMICAL COMPANY, LIMITED

  公开号：EP0357372A2

  公开（公告）日：1990-03-07

  Disclosed are herein optically active ester derivatives represented by the formula (I): (wherein R1 represents an alkyl group having 3 to 20 carbon atoms; R2 represents an optically active alkyl or alkoxyalkyl group having 3 to 15 carbon atoms optionally substituted by halogen atoms; Y represents -O-, -COO- or -OCO-; X represents -COO- or -OCO-; represents a number of 1 or 2; k and m each represents a number of 0 or 1; n represents a numberof 1 to 6), preparation processes therefor, liquid crystal materials containing such easter derivatives as active ingredient, and a light switching element using said liquid crystal materials as liquid crystal element.

  本文公开了由式(I)代表的光学活性酯衍生物： (其中 R1 代表具有 3 至 20 个碳原子的烷基；R2 代表具有 3 至 15 个碳原子的光学活性烷基或烷氧基烷基，可选择被卤素原子取代；Y 代表 -O-、-COO- 或 -OCO-；X 代表 -COO- 或 -OCO-；代表 1 或 2 的数字；k 和 m 分别代表 0 或 1 的数字；n 代表 1 至 6 的数字）、其制备工艺、含有此类酯衍生物作为活性成分的液晶材料，以及使用上述液晶材料作为液晶元件的光开关元件。
• The Interplay of Spacer Chirality and Parity in Mesogenic Dimers
  作者：Antonija Ožegović、Anamarija Knežević、Jurica Novak、Suzana Šegota、Patrick Davidson、Andreja Lesac

  DOI：10.1002/cphc.202400065

  日期：——

  (S)-3-phenyl-3-hydroxypropanoic acid enables the synthesis of novel LC dimers with a chiral flexible spacer of different lengths. This work highlights the importance of the position of the chiral group within the dimeric molecule and demonstrates the complexity of chirality transfer from molecular to multiple levels of structural chirality.

  关键片段 ( S )-3-苯基-3-羟基丙酸能够合成具有不同长度的手性柔性间隔基的新型 LC 二聚体。这项工作强调了二聚体分子中手性基团位置的重要性，并证明了从分子到多个结构手性水平的手性转移的复杂性。
• AZABICYCLO COMPOUNDS AS CALCIUM CHANNEL ANTAGONISTS
  申请人：SMITHKLINE BEECHAM PLC

  公开号：EP0625981A1

  公开（公告）日：1994-11-30
• US5124070A
  申请人：——

  公开号：US5124070A

  公开（公告）日：1992-06-23
• US5264151A
  申请人：——

  公开号：US5264151A

  公开（公告）日：1993-11-23