5-acetamido-1,3,3-trimethyl-2-methyleneindoline | 41382-29-0

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吲哚及其衍生物
• 英文名称: 5-acetamido-1,3,3-trimethyl-2-methyleneindoline
• 英文别名: 5-N-acetylamino-1,3,3-trimethyl-2-methylene-indoline；1,3,3-Trimethyl-2-methylene-5-acetylaminoindoline；N-(1,3,3-trimethyl-2-methylideneindol-5-yl)acetamide
• CAS: 41382-29-0
• 化学式: C₁₄H₁₈N₂O
• 分子量: 230.31
• InChiKey: OUOWMQSMDSLZBA-UHFFFAOYSA-N

物化性质

• 熔点：
  123-124 °C(Solv: heptane (142-82-5))
• 沸点：
  401.7±45.0 °C(Predicted)
• 密度：
  1.10±0.1 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  2.6
• 重原子数：
  17
• 可旋转键数：
  1
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.36
• 拓扑面积：
  32.3
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  5-acetamido-1,3,3-trimethyl-2-methyleneindoline 、 1-氨基-2-萘酚 在 碳酸氢钠 、 magnesium sulfate 作用下， 以 二甲基亚砜 、 甲苯 为溶剂， 反应 4.0h， 以69%的产率得到5-acetylamino-1,3,3-trimethylspiro(indoline-2,3'-[3H]naphth[2,1-b][1,4]oxazine)
  参考文献：
  名称：

  Synthesis of photochromic spirooxazines from 1-amino-2-naphthols

  摘要：

  A synthetic access to photochromic spirooxazines is developed through the condensation of methylene-substituted azaheterocycles on 1-amino-2-naphthols in presence of an oxidizing agent. Compared to usual preparation of this kind of compounds (via 1-nitroso-2-naphthols), yields are generally good and approaches to Further spiroheterocyclic oxazines are possible. (C) 1997 Elsevier Science Ltd.

  DOI：

  10.1016/s0040-4020(97)00640-6
• 作为产物：
  描述：

  5-氨基-2-亚甲基-1,3,3-三甲基二氢吲哚 、 乙酰氯 在 三乙胺 作用下， 以 苯 为溶剂， 反应 24.0h， 以86%的产率得到5-acetamido-1,3,3-trimethyl-2-methyleneindoline
  参考文献：
  名称：

  取代了2-甲基和2-亚甲基二氢吲哚。3.硝基氨基5,6-二取代的2-甲基和2-亚甲基二氢吲哚

  摘要：

  DOI：

  10.1007/bf00476978

文献信息

• Agent and method for oxidative coloring of keratin fibers
  申请人：Pasquier Cecile

  公开号：US20070067927A1

  公开（公告）日：2007-03-29

  The object of the present invention is a ready-to-use agent for coloring keratin fibers containing (i) at least one heterocyclic hydrazone derivative of formula (I), (ii) at least one aromatic enamine of formula (IIa) or an acid addition compound thereof (IIb) and (iii) at least one oxidant, a multicomponent kit and a method for coloring keratin fibers by use of said agent.

  本发明的对象是一种用于着色角蛋白纤维的即用剂，包含（i）至少一种式（I）的杂环腙衍生物，（ii）至少一种式（IIa）的芳香胺或其酸加合物（IIb），以及（iii）至少一种氧化剂，以及通过使用该剂着色角蛋白纤维的多组分套件和方法。
• Agent for dyeing fibers comprising an indoline/indolium derivative
  申请人：——

  公开号：US20030079301A1

  公开（公告）日：2003-05-01

  The object of the present invention is an agent for dyeing fibers obtained by mixing two components and characterized in that one component (component A2) contains at least one carbonyl compound and the other component (component A1) contains at least one indoline derivative of formula (I) or a 3H-indoline derivative of formula (Ia) 1 as well as a multicomponent kit for dyeing and later decolorizing fibers, said kit containing both an agent according to the invention for producing a coloration on the fiber and an agent for the reductive removal of said coloration.

  本发明的对象是一种通过混合两种组分获得的染色纤维的染色剂，其特征在于一个组分（组分A2）含有至少一种羰基化合物，另一个组分（组分A1）含有至少一种式（I）的吲哚衍生物或式（Ia）的3H-吲哚衍生物，以及一种用于染色和后期脱色纤维的多组分套件，该套件包含根据本发明用于在纤维上产生着色的染色剂以及用于还原去除所述着色的染色剂。
• Agent for coloring fibers and method for temporarily coloring fibers
  申请人：——

  公开号：US20020172651A1

  公开（公告）日：2002-11-21

  The object of the present invention is a preparation for coloring fibers, which is prepared before use by mixing an acidic component (A1), containing at least one enamine of Formula (I)/(Ia) with a component (A2), containing a Schiff's base of Formula (II) 1 as well as a method for temporarily coloring fibers, for which the coloration, obtained with the aforementioned coloring agent, can be removed once again at any time by a sulfite-colorizing agent.

  本发明的对象是一种用于染色纤维的制剂，该制剂在使用前通过混合含有至少一种Formula（I）/（Ia）的恩胺的酸性组分（A1）与含有Formula（II）的席夫碱基的组分（A2）制备而成。同时提供了一种临时染色纤维的方法，其中使用上述染色剂获得的着色可以随时通过亚硫酸盐染色剂再次去除。
• Complete1H and13C NMR spectral assignment of symmetric and asymmetric bis-spiropyran derivatives
  作者：Sam-Rok Keum、Hyo-Jung Roh、Yoon-Ki Choi、Soon-Sung Lim、Sung-Hoon Kim、Kwangnak Koh

  DOI：10.1002/mrc.1640

  日期：2005.10

  1H and 13C NMR spectra of symmetric and asymmetric bis‐spiropyrans, Series 1‐3, were completely assigned. Especially, the 1H assignment of asymmetric spiropyrans was achieved by utilizing 1H–1H COSY and nOe experiments. All of the carbons in the dye molecules were investigated through a combination of heteronuclear 2D‐shift correlation spectroscopy (HETCOR), together with an attached proton test (APT)

  对称和不对称双螺吡喃系列 1-3 的 1H 和 13C NMR 谱完全归属。特别是，不对称螺吡喃的 1H 分配是通过利用 1H-1H COZY 和 nOe 实验实现的。通过异核 2D 位移相关光谱 (HETCOR) 和附着质子测试 (APT) 的组合研究染料分子中的所有碳。版权所有 © 2005 John Wiley & Sons, Ltd.
• Photochromic compounds
  申请人：James Robinson Limited

  公开号：US06303673B1

  公开（公告）日：2001-10-16

  A photochromic compound has the formula (I) wherein R1 is selected from the group including substituted amino aryl moieties, substituted cyclic amino aryl moieties and substituted N-indolinoaryl or N-tetrahydroquinolino aryl groups, R3 is selected from the group including linear or branched C1-C20 alkyl, linear or branched C2-C20 alkenyl or polyalkenyl, C2-C20 alkynyl or polyalkynyl, aryl, heteroaryl, linear or branched C1-C20 alkyl aryl, linear or branched C1-C20 alkyl-cycloalkyl or -bicycloalkyl or -tricycloalkyl or substituted -cycloalkyl or -bicycloalkyl or -tricycloalkyl, linear or branched C1-C20 haloalkyl or perhaloalkyl, linear or branched C1-C20 alkoxyalkyl or peralkoxyalkyl, linear or branched C1-C20 alkylthioalkyl or peralkylthioalkyl, linear or branched C1-C20 amino alkyl or peraminoalkyl, C3-C20 cycloalkyl or substituted cycloalkyl, C4-C20 bicycloalkyl or substituted bicycloalkyl, C6-C20 tricycloalkyl or substituted tricycloalkl or linear or branched C1-C20 hydroxyalkyl or perhydroxyalkyl; R4 and R5 which may be the same or different are R3 or R4 and R5 are conjoined to form a spiro linked C3-C20 cyclic system or substituted cyclic system; and wherein R2 and R6 are each selected from R3 or hydrogen, halogen, nitro, nitroso, amino, acetamido, C2-C10 N-alkylamido, alkoxycarbonyl, nitrile, carboxy, hydroxy, aryloxy, C1-C10 alkoxy, a heteroatom which is O or N or S or P which in turn can be bonded either singly or multiply to carbon, oxygen, sulphur or nitrogen, C1-C5 alkoxy or alkylthio or aryl or aryloxy or multiples thereof.

  一种光致变色化合物具有下列式(I)：其中R1选自包括取代氨基芳基基团、取代环状氨基芳基基团以及取代的N-吲哚基芳基或N-四氢喹啉基芳基基团的群体；R3选自包括线性或支链C1-C20烷基、线性或支链C2-C20烯基或多烯基、C2-C20炔基或多炔基、芳基、杂芳基、线性或支链C1-C20烷基芳基、线性或支链C1-C20烷基-环状烷基或-双环烷基或-三环烷基或取代的-环状烷基或-双环烷基或-三环烷基、线性或支链C1-C20卤代烷基或全卤代烷基、线性或支链C1-C20烷氧基烷基或全烷氧基烷基、线性或支链C1-C20烷硫基烷基或全烷硫基烷基、线性或支链C1-C20氨基烷基或全氨基烷基、C3-C20环状烷基或取代的环状烷基、C4-C20双环烷基或取代的双环烷基、C6-C20三环烷基或取代的三环烷基或线性或支链C1-C20羟基烷基或全羟基烷基；R4和R5可以相同也可以不同，R3或R4和R5相连形成螺环连接的C3-C20环状系统或取代的环状系统；其中R2和R6各自选自R3或氢、卤素、硝基、亚硝基、氨基、乙酰胺基、C2-C10 N-烷基酰胺基、烷氧羰基、腈基、羧基、羟基、芳基氧基、C1-C10烷氧基、是O或N或S或P的杂原子，该杂原子又可以单重或多重地与碳、氧、硫或氮结合，C1-C5烷氧基或烷硫基或芳基或芳基氧基或其多重组合。