2-ethyl-1-hexen-3-one | 4436-98-0

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 2-ethyl-1-hexen-3-one
• 英文别名: Ethylpropylacrolein；3-methylideneheptan-4-one
• CAS: 4436-98-0
• 化学式: C₈H₁₄O
• 分子量: 126.199
• InChiKey: MBLXROIYHWIVRL-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.2
• 重原子数：
  9
• 可旋转键数：
  4
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.62
• 拓扑面积：
  17.1
• 氢给体数：
  0
• 氢受体数：
  1

安全信息

• 海关编码：
  2914190090

反应信息

• 作为反应物：
  描述：

  2-ethyl-1-hexen-3-one 生成 Cyclobutyl-propyl-keton
  参考文献：
  名称：

  Photochemical rearrangements of .alpha.-methylene ketones

  摘要：

  DOI：

  10.1021/ja00796a019
• 作为产物：
  描述：

  1-Acetoxy-2-aethylhexan-3-on 在 1,8-二氮杂双环[5.4.0]十一碳-7-烯 作用下， 以 苯 为溶剂， 反应 3.0h， 以90%的产率得到2-ethyl-1-hexen-3-one
  参考文献：
  名称：

  α-亚甲基羰基化合物的新合成

  摘要：

  α-亚甲基羰基化合物是在催化量的弱碱存在下，通过α-硝基酮或α-硝基酯与37％甲醛的反应，然后乙酰化，用Bu 3 SnH脱硝并消除乙酸来区域选择性制备的。

  DOI：

  10.1016/s0040-4039(00)86017-7

文献信息

• APPARATUS FOR PRODUCING ALCOHOLS FROM OLEFINS
  申请人：Ko Dong-Hyun

  公开号：US20110282108A1

  公开（公告）日：2011-11-17

  The present invention relates to an apparatus for producing alcohols from olefins, comprising: a hydroformylation reactor wherein aldehydes are produced from olefins; a catalyst/aldehydes separator; a hydrogenation reactor wherein the aldehydes are hydrogenated to produce alcohols; and a distillation column. The hydroformylation reactor is equipped with a distributor plate, which has a broad contact surface for providing sufficient reaction area for reactants such as olefins and synthesis gas, and allows the reaction mixture to circulate and mix sufficiently, which contribute to excellent efficiency in terms of production of aldehydes. In addition, the hydrogenation reactor suppresses sub-reactions to improve the production yield of alcohols.

  本发明涉及一种从烯烃生产醇的装置，包括：一个氢甲酰化反应器，其中从烯烃生产醛；一个催化剂/醛分离器；一个加氢反应器，其中将醛加氢生成醇；以及一个蒸馏塔。氢甲酰化反应器配备有一个分布板，该板具有广泛的接触表面，为烯烃和合成气等反应物提供足够的反应区域，并允许反应混合物循环和充分混合，这有助于在生产醛方面实现卓越的效率。此外，加氢反应器抑制次级反应，提高醇的产量。
• Process for Production of Purified Alcohols
  申请人：Oota Hirofumi

  公开号：US20080242899A1

  公开（公告）日：2008-10-02

  A process for producing purified alcohols yielding good results in the acid wash color test which comprises the condensation step of subjecting an aldehyde to aldol condensation and dehydration to obtain a corresponding condensate, the hydrogenation step of hydrogenating the condensate into a crude alcohol, and the purification step of distilling the crude alcohol to obtain a purified alcohol, characterized by feeding into the purification step a crude alcohol containing compounds having oxygenic heterocycles bearing carbon-carbon double bonds in the cycle in a concentration of as low as 200 ppm by weight or below. In particular, the aldehyde is n-butyraldehyde, the condensate is 2-ethylhexenal, and the alcohol is 2-ethylhexanol.

  生产纯化醇的方法，在酸洗色测中获得良好结果，包括对醛进行醛缩聚和脱水的缩聚步骤，将醛缩聚产物氢化为粗醇的氢化步骤，以及蒸馏粗醇以获得纯化醇的纯化步骤，其特征在于将含有含氧杂环、环中含有碳-碳双键的化合物的粗醇，以重量浓度低至200 ppm或以下的浓度送入纯化步骤。特别地，醛是正丁醛，缩聚产物是2-乙基己烯醛，醇是2-乙基己醇。
• [EN] PROCESS FOR THE PRODUCTION OF 2-ALKYLALKANOL<br/>[FR] PROCÉDÉ DE PRODUCTION DE 2-ALKYLALCANOL
  申请人：JOHNSON MATTHEY DAVY TECHNOLOGIES LTD

  公开号：WO2018069714A1

  公开（公告）日：2018-04-19

  A process for the production of 2-alkylalkanol from an aldehyde is disclosed. The process comprises the steps of: feeding aldehyde to a reactor (42) operated under condensation and dehydration conditions such that reaction occurs and an unsaturated aldehyde is produced; recovering a stream from the reactor (42) comprising the unsaturated aldehyde and feeding said stream to a first hydrogenation reactor (45) operated under conditions such that at least some of the unsaturated aldehyde is converted to 2-alkylalkanol; recovering the stream from the first hydrogenation reactor (45) comprising the 2-alkylalkanol, one or more of unreacted acrolein, alkylalkenol and alkylalkanal and heavies; passing the stream recovered from the first hydrogenation reactor (45) to a first distillation zone (48) where at least some of the heavies are separated from the stream; recovering a stream from the first distillation zone (48) comprising the 2-alkylalkanol, one or more of unreacted acrolein, alkylalkenol and alkylalkanal, said stream having a reduced heavies content when compared to the stream fed to the first distillation zone (48), and feeding said stream to a second hydrogenation reactor (51) operated under conditions such that at least one of the unreacted acrolein, alkylalkenol and alkylalkanal are converted to 2-alkylalkanol; and recovering a stream from the second hydrogenation reactor (51) comprising an increased 2-alkylalkanol content compared to the stream fed to the second hydrogenation reactor (51).

  本发明公开了一种从醛生产2-烷基醇的方法。该方法包括以下步骤：将醛送入在缩合和脱水条件下操作的反应器（42），使反应发生并产生不饱和醛；从反应器（42）中回收包含不饱和醛的流，并将该流送入第一氢化反应器（45），在条件下操作，使至少一部分不饱和醛转化为2-烷基醇；从第一氢化反应器（45）中回收包含2-烷基醇、未反应的丙烯醛、烷基烯醇和烷基醛以及重质的流；将从第一氢化反应器（45）回收的流经过到第一蒸馏区（48），至少分离出一部分重质；从第一蒸馏区（48）中回收包含2-烷基醇、未反应的丙烯醛、烷基烯醇和烷基醛的流，与送入第一蒸馏区（48）的流相比，其重质含量降低，并将该流送入第二氢化反应器（51），在条件下操作，使未反应的丙烯醛、烷基烯醇和烷基醛之一转化为2-烷基醇；从第二氢化反应器（51）中回收包含比送入第二氢化反应器（51）的流更高的2-烷基醇含量的流。
• Process for removing triorganophosphine from a liquid composition
  申请人：UNION CARBIDE CORPORATION

  公开号：EP0019296A1

  公开（公告）日：1980-11-26

  Process for removing triorganophosphine from a rhodium-contaiing composition which is based on the reaction of phosphines with α-β unsaturated compounds.

  根据膦与α-β不饱和化合物的反应，从铑包覆组合物中去除三有机膦的工艺。
• Process for preparing adjacently disubstituted ketones, novel prostaglandins E1 and anti-thrombotic compositions containing them
  申请人：TEIJIN LIMITED

  公开号：EP0019475A2

  公开（公告）日：1980-11-26

  Novel 7-hydroxyprostaglandins E1, or stereoisomers thereof, or protected derivatives thereof, having the following formula: wherein R3 represents H, CH3 or C2H5, R9 represents H or CH3, R10 and R are identical or different, and each represents H, tetrahydropyranyl or t-butyldimethylsilyl. Also provided is a process for producing adjacently disubstituted ketones including the above novel compounds, which process comprises reacting an a, #-unsaturated carbonyl compound with a cuprous salt and an organolithium compound in an aprotic inert organic medium in the presence of trialkylphosphine, the amounts of said cuprous salt and said organolithium compound being substantially equimolar, and reacting the product with a protected acetal derivative of an organic carbonyl compound or an aldehyde in the presence of a Lewis acid if necessary followed by reacting the product with a proton donor.

  具有下式的新型 7-羟基前列腺素 E1 或其立体异构体或其保护衍生物： 其中 R3 代表 H、CH3 或 C2H5，R9 代表 H 或 CH3，R10 和 R 相同或不同，且各自代表 H、四氢吡喃基或叔丁基二甲基硅基。 还提供了一种生产包括上述新型化合物在内的邻接二取代酮的工艺，该工艺包括在三 烷基膦存在下，在氩惰性有机介质中使 a，#-不饱和羰基化合物与亚铜盐和有机锂化合物 反应、所述亚铜盐和所述有机锂化合物的量基本等摩尔，必要时在路易斯酸存在下，使产物与有机羰基化合物或醛的受保护缩醛衍生物反应，然后使产物与质子供体反应。