2,2'-biimidazole | 113449-19-7

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 氮杂环化合物
• 英文名称: 2,2'-biimidazole
• 英文别名: 2,2′-biimidazole；2,2’-biimidazole；H₂biim；2-(2H-imidazol-2-ylidene)-2H-imidazole；2-imidazol-2-ylideneimidazole
• CAS: 113449-19-7
• 化学式: C₆H₄N₄
• 分子量: 132.125
• InChiKey: HVEHTNLSYGZELD-UHFFFAOYSA-N

物化性质

• 沸点：
  139.9±50.0 °C(Predicted)
• 密度：
  1.45±0.1 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  -1
• 重原子数：
  10
• 可旋转键数：
  0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  49.4
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  2,2'-biimidazole 在 potassium dihydrogenphosphate 、 次氯酸叔丁酯 、 硫酸 、 硝酸 、 potassium hydroxide 作用下， 以 水 、 乙酸乙酯 为溶剂， 反应 5.17h， 生成
  参考文献：
  名称：

  CN115490694

  摘要：

  公开号：
• 作为产物：
  描述：

  N⁴,N⁵,N^4',N^5'-Tetrakis-(3-trifluoromethyl-phenyl)-[2,2']biimidazolylidene-4,5,4',5'-tetraamine 在 溶剂黄146 、 锌 作用下， 反应 48.0h， 以9%的产率得到2,2'-biimidazole
  参考文献：
  名称：

  Stabile Tetraazafulvalene - Synthesen und Folgechemie

  摘要：

  The syntheses, properties and reactions are described for 1,3,6,7-tetrakis[arylamino]-1,4,5,8-tetraazafulvalenes and their vinylogous derivatives. First, the acylation of form-as well as acetamidine with bis-imidoylchlorides derived from oxalic acid 6 formed reactive cyclic intermediates which dimerized to tetraazafulvalenes 12 or bisvinylogous tetraazafulvalenes 14. Based on, a further synthesis was found using a cycloacylation reaction of amidines with imidoylchlorides 6 followed by prototropic migration of alpha-hydrogen. Thus, the vinylogous compound 15 and the phenylogous derivatives 16, 17 could be isolated in moderate up to good yields. Besides amidines, other derivatives of carboxylic acids as amides or thioamides could be transformed into corresponding tetraazafulvalenes 18-20. Due to their vicinal amino groups, alkylation and acylation reactions were studied. For example, the reaction with orthoformates yielded the ring fused products 24a,b which may be starting material for carbenes just as the cyclization product with thiophosgene 27. Treatment of tetraazafulvalenes with anhydrous iron-II salts or molybdenum hexacarbonyl yielded the deeply colored metal diazadiene complexes 33 and 34. Finally, reduction using metallic lithium and subsequent alkylation constitutes a convenient synthetic entry to heterocyclic analogues of stilbene 37.

  DOI：

  10.1002/prac.19983400406
• 作为试剂：
  描述：

  7-溴-5-氯吲哚 在 盐酸 、 copper(l) iodide 、 铜 、 potassium carbonate 、 caesium carbonate 、 2,2'-biimidazole 作用下， 以 四氢呋喃 、 水 、 硝基苯 、 N,N-二甲基甲酰胺 为溶剂， 反应 13.08h， 生成 4-chloro-6H-pyrrolo[3,2,1-de]phenazine
  参考文献：
  名称：

  유기 화합물 및 이를 포함하는 유기 전계 발광 소자

  摘要：

  本发明涉及一种新型的苯并噻吩类化合物，具有优异的载流子注入能力、载流子输运能力和发光能力，并通过将所述苯并噻吩类化合物包含在有机层中，提高了有机电致发光器件的发光效率、驱动电压和寿命等特性。

  公开号：

  KR20160124409A

文献信息

• [EN] PHOTOACTIVATED MOLECULES FOR LIGHT-INDUCED MODULATION OF THE ACTIVITY OF ELECTRICALLY EXCITABLE CELLS AND METHODS OF USING SAME<br/>[FR] MOLÉCULES PHOTO-ACTIVÉES POUR PHOTO-MODULATION DE L'ACTIVITÉ DE CELLULES ÉLECTRIQUEMENT EXCITABLES ET PROCÉDÉS D'UTILISATION ASSOCIÉS
  申请人：UNIV SOUTHERN CALIFORNIA

  公开号：WO2014100283A1

  公开（公告）日：2014-06-26

  Methods and compositions modulate the activity of electrically excitable cells. Photovoltaic compounds which, upon exposure to light energy, increase or decrease the electrical activity of cells. These supplement and/or replace of vision based on the conversion of light energy to electrical energy within certain cells of the visual system. A "patch" or bridge to circumvent one or more defective, damaged, or diseased cells in the visual system. Additionally, in several embodiments, subjects with normal vision can benefit from the methods, compositions, systems, and/or devices disclosed herein as normal visual acuity can be heightened. The exposure induces an energy (e.g., a receipt of light energy, conversion to electrical energy, and passage of that electrical energy) from the photovoltaic compound to the cell, thereby altering the transmembrane potential of the cell and/or the opening of one or more ion channels, thereby modulating the activity of the electrically excitable cell.

  方法和配方调节电兴奋细胞的活动。光电池化合物，在受到光能照射时，增加或减少细胞电活动。这些补充和/或替代基于将光能转化为视觉系统内某些细胞的电能的视觉。一种“贴片”或桥梁，用以绕过视觉系统中的一个或多个缺陷、损坏或病变细胞。此外，在多种实施方式中，正常视力的受试者也可以从本公开的方法、配方、系统或设备中受益，因为正常视力可以增强。照射引发能量（例如，接收光能，转化为电能，并传递该电能）从光电池化合物到细胞，从而改变细胞的跨膜电位和/或打开一个或多个离子通道，从而调节电兴奋细胞的活动。
• [EN] PHOTOACTIVATED MOLECULES FOR LIGHT-INDUCED MODULATION OF THE ACTIVITY OF ELECTRICALLY EXCITABLE CELLS AND METHODS OF USING<br/>[FR] MOLÉCULES PHOTOACTIVÉES POUR LA MODULATION INDUITE PAR LA LUMIÈRE DE L'ACTIVITÉ DES CELLULES ÉLECTRIQUEMENT EXCITABLES ET PROCÉDÉS D'UTILISATION
  申请人：UNIV SOUTHERN CALIFORNIA

  公开号：WO2017031380A1

  公开（公告）日：2017-02-23

  Disclosed herein are methods and compositions for the modulation of the activity of electrically excitable cells. In particular, several embodiments relate to the use of photovoltaic compounds which, upon exposure to light energy, increase or decrease the electrical activity of cells.

  公开了用于调节电兴奋性细胞活动的方法和组合物。特别是，几个实施例涉及使用光伏化合物，该化合物在暴露于光能时增加或减少细胞的电活动。
• A new hexamolybdate-based copper–2,2′-biimidazole coordination polymer serving as an acid catalyst and support for enzyme immobilization
  作者：Xiao-Jing Sang、Shu-Li Feng、Ying Lu、Yue-Xian Zhang、Fang Su、Lan-Cui Zhang、Zai-Ming Zhu

  DOI：10.1107/s2053229618013037

  日期：2018.11.1

  [Cu(H2biim)(H2O)]2+ ions in a pentacoordinate mode via four terminal O atoms, resulting in a tetra‐supported structure, and each CuII ion is shared by two adjacent Mo6O20 units. Infinite one‐dimensional chains are established by linkage between two adjacent Mo6O20 units and two CuII ions, and these chains are further packed into a three‐dimensional framework by hydrogen bonds, π–π interactions and electrostatic

  （NH 4）3 [CoMo 6 O 24 H 6 ]·7H 2 O（CoMo 6），CuCl 2 ·2H 2 O和2,2'-联咪唑（H 2 biim）的水热反应导致形成新的配位聚合物，即聚[二水合二（2,2'-联咪唑）六μ 3 -氧代-辛μ 2 -氧代- hexaoxodicopper（II）hexamolybdate（VI）]，[铜2沫6 ø 20（C 6 H 6 N 4）2（H 2 O）2 ]n（ Cu-Mo 6 O 20），pH 2-3。显然，在结晶Cu-Mo 6 O 20的形成过程中，杂多钼酸钼CoMo 6的原始Anderson型骨架被破坏，新的异聚六钼酸Mo 6 O 20单元被组装。在铜钼6 ø 20，一个沫6 ö 20单元连接4 [铜（H 2 biim）（H 2 O）] 2+离子在五配位模式通过四个末端的O原子，形成四支撑结构，每个Cu II离子被两个相邻的Mo 6 O 20单元共享。通过两个相邻的Mo
• BINUCLEAR METAL COMPLEX, AND ORGANIC ELECTROLUMINESCENCE ELEMENT USING SAME
  申请人：Ube Industries, Ltd.

  公开号：EP2647642A1

  公开（公告）日：2013-10-09

  The present invention relates to a novel binuclear metal complex, which has, for example, a biimidazole as a bridging ligand and is useful in particular as a material for an organic electroluminescence element.

  本发明涉及一种新型双核金属配合物，例如具有双咪唑作为桥联配体，并且特别适用作为有机电致发光元件的材料。
• [EN] ORGANIC ELECTROLUMINESCENT DEVICE<br/>[FR] DISPOSITIF ÉLECTROLUMINESCENT ORGANIQUE
  申请人：COMMW SCIENT IND RES ORG

  公开号：WO2012051666A1

  公开（公告）日：2012-04-26

  An organic electroluminescent device comprising: a pair of electrodes comprising an anode and a cathode, and one or more layers arranged between the anode and the cathode; wherein at least one of the one or more layers is a light emitting layer and wherein the one or more layers, comprises an organic compound represented by a substituted 2,2'-biimidazole. The substitutents on the biimidazole may be selected form a range of suitable substituents, including: hydrogen, a substituted or unsubstituted heterocyclic group, a substituted or unsubstituted alkyl group, a substituted or unsubstituted aralkyl group, a substituted aryl group containing at least one atom selected from the group consisting of N, O, S, Si, P, F, Cl, Br; and/or comprising at least three organic rings, the organic rings being fused or non-fused, or a number of the adjacent substituent sites may together form a substituted or unsubstituted cyclic group; furthermore some substituents may be the same or different and may be selected from the group consisting of: hydrogen, deuterium, a substituted or unsubstituted alkyl group, a halogen atom or a cyano group.

  一种有机电致发光器件，包括：一对电极，包括阳极和阴极，以及安排在阳极和阴极之间的一个或多个层；其中一个或多个层中至少有一层是发光层，而且一个或多个层包括由取代的2,2'-联吡唑表示的有机化合物。联吡唑上的取代基可以从一系列适当的取代基中选择，包括：氢、取代或未取代的杂环基、取代或未取代的烷基、取代或未取代的芳基、含有来自N、O、S、Si、P、F、Cl、Br的至少一个原子的取代芳基；和/或包括至少三个有机环，这些有机环被融合或非融合，或者相邻取代位点的一些可能共同形成取代或未取代的环状基团；此外，一些取代基可能相同或不同，并且可以从氢、氘、取代或未取代的烷基、卤素原子或氰基的组中选择。