2-Cyano-acrylic acid 2,3,3-trichloro-1-methyl-allyl ester | 163435-31-2

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: 2-Cyano-acrylic acid 2,3,3-trichloro-1-methyl-allyl ester
• 英文别名: 3,4,4-Trichlorobut-3-en-2-yl 2-cyanoprop-2-enoate
• CAS: 163435-31-2
• 化学式: C₈H₆Cl₃NO₂
• 分子量: 254.5
• InChiKey: NYUZOKQAMICONM-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.2
• 重原子数：
  14
• 可旋转键数：
  4
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.25
• 拓扑面积：
  50.1
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  聚合甲醛 、 2,2,3-trichloro-1-methyl-2-propenyl cyanoacetate 在 哌啶 、 phosphorus pentoxide 、 对甲苯磺酸 、 对苯二酚 作用下， 生成 2-Cyano-acrylic acid 2,3,3-trichloro-1-methyl-allyl ester
  参考文献：
  名称：

  Synthesis of functionally substituted 2-cyanoacrylates

  摘要：

  The conditions for the Knoevenagel synthesis of 2-cyanoacrylates containing double and triple bonds in the alkoxycarbonyl group have been studied. It was found that the esters are formed in 10-70 % yields by the condensation of the respective cyanoacetates with formaldehyde in the 1 : 1 ratio in the presence of piperidine, followed by the pyrolysis of the oligomers formed in vacao at 170-200 degrees C in the presence of para-toluenesulfonic acid. The compounds synthesized readily undergo polymerization at room temperature and can be used as the basis for thermostable rapidly polymerizing adhesives.

  DOI：

  10.1007/bf00699831

文献信息

• Synthesis of functionally substituted 2-cyanoacrylates
  作者：T. I. Guseva、N. G. Senchenya、K. A. Mager、V. A. Tsyryapkin、Yu. G. Gololobov

  DOI：10.1007/bf00699831

  日期：1994.4

  The conditions for the Knoevenagel synthesis of 2-cyanoacrylates containing double and triple bonds in the alkoxycarbonyl group have been studied. It was found that the esters are formed in 10-70 % yields by the condensation of the respective cyanoacetates with formaldehyde in the 1 : 1 ratio in the presence of piperidine, followed by the pyrolysis of the oligomers formed in vacao at 170-200 degrees C in the presence of para-toluenesulfonic acid. The compounds synthesized readily undergo polymerization at room temperature and can be used as the basis for thermostable rapidly polymerizing adhesives.