1-(9H-carbazol-1-yl)-3-(1H-indol-7-yl)urea | 1154733-19-3

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吲哚及其衍生物
• 英文名称: 1-(9H-carbazol-1-yl)-3-(1H-indol-7-yl)urea
• CAS: 1154733-19-3
• 化学式: C₂₁H₁₆N₄O
• 分子量: 340.384
• InChiKey: QNAGBZGWGCZJIY-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.1
• 重原子数：
  26
• 可旋转键数：
  2
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  72.7
• 氢给体数：
  4
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  1-(9H-carbazol-1-yl)-3-(1H-indol-7-yl)urea 、 四丁基醋酸铵 以 氘代二甲亚砜 、 水 为溶剂， 生成
  参考文献：
  名称：

  Fluorescent carbazolylurea- and carbazolylthiourea-based anion receptors and sensors

  摘要：

  A series of carbazolylurea- and carbazolylthiourea-based receptors have been synthesised and their anion complexation and fluorescence properties were studied. The urea compounds show selectivity for oxo-anion complexation over chloride and the fluorescence of compound 1 is selectively quenched by benzoate anions in DMSO/0.5% water. However, the thiourea compounds show reduced anion affinities compared to the urea analogues.

  DOI：

  10.1080/10610271003637087
• 作为产物：
  描述：

  1-isocyanato-9H-carbazole 、 7-氨基吲哚 在 三乙胺 作用下， 以 氯仿 为溶剂， 以26%的产率得到1-(9H-carbazol-1-yl)-3-(1H-indol-7-yl)urea
  参考文献：
  名称：

  Fluorescent carbazolylurea anion receptors

  摘要：

  我们合成了一系列荧光咔唑脲碱阴离子受体，它们对氧化阴离子（尤其是碳酸氢盐和醋酸盐）具有很高的亲和力。在 DMSO-0.5% 的水中加入苯甲酸阴离子后，二咔唑脲（1）的荧光会被淬灭。

  DOI：

  10.1039/b900178f

文献信息

• Stabilisation of alkylcarbamate anions using neutral hydrogen bond donors
  作者：Peter R. Edwards、Jennifer R. Hiscock、Philip A. Gale

  DOI：10.1016/j.tetlet.2009.06.058

  日期：2009.8

  urea-based anion receptors and alkylcarbamate species formed by the reaction of carbon dioxide with primary amines have been investigated by 1H NMR. Significant downfield shifts in the NH proton signals of the receptors in the presence of the alkylcarbamates were observed, consistent with classical host:anion hydrogen-bonding. This observation demonstrates that neutral hydrogen bond donor receptors can compete

  通过1 H NMR研究了一系列基于脲的阴离子受体与二氧化碳与伯胺反应形成的烷基氨基甲酸酯的相互作用。观察到在烷基氨基甲酸酯的存在下，受体的NH质子信号发生明显的下移，这与经典的主体：阴离子氢键一致。该观察表明，中性氢键供体受体可与铵阳离子竞争以结合DMSO- d 6溶液中的氨基甲酸酯。
• Fluorescent carbazolylurea- and carbazolylthiourea-based anion receptors and sensors
  作者：Jennifer R. Hiscock、Philip A. Gale、Claudia Caltagirone、Michael B. Hursthouse、Mark E. Light

  DOI：10.1080/10610271003637087

  日期：2010.11.1

  A series of carbazolylurea- and carbazolylthiourea-based receptors have been synthesised and their anion complexation and fluorescence properties were studied. The urea compounds show selectivity for oxo-anion complexation over chloride and the fluorescence of compound 1 is selectively quenched by benzoate anions in DMSO/0.5% water. However, the thiourea compounds show reduced anion affinities compared to the urea analogues.
• Fluorescent carbazolylurea anion receptors
  作者：Jennifer R. Hiscock、Claudia Caltagirone、Mark E. Light、Michael B. Hursthouse、Philip A. Gale

  DOI：10.1039/b900178f

  日期：——

  A series of fluorescent carbazolylurea base anion receptors have been synthesised that show a high affinity for oxo-anions (particularly bicarbonate and acetate). The fluorescence of dicarbazolylurea (1) is quenched upon addition of benzoate anions in DMSO–0.5% water.

  我们合成了一系列荧光咔唑脲碱阴离子受体，它们对氧化阴离子（尤其是碳酸氢盐和醋酸盐）具有很高的亲和力。在 DMSO-0.5% 的水中加入苯甲酸阴离子后，二咔唑脲（1）的荧光会被淬灭。