cis-1-Phenyl-2-benzoyl-2-carboxy-aethen | 64235-44-5

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 直链 1,3-二芳基丙烷
• 英文名称: cis-1-Phenyl-2-benzoyl-2-carboxy-aethen
• 英文别名: (E)-2-benzoyl-3-phenylprop-2-enoic acid
• CAS: 64235-44-5
• 化学式: C₁₆H₁₂O₃
• 分子量: 252.269
• InChiKey: UMPNMJHTRNHHAL-SDNWHVSQSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4
• 重原子数：
  19
• 可旋转键数：
  4
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  54.4
• 氢给体数：
  1
• 氢受体数：
  3

文献信息

• Extracts of Isochrysis sp.
  申请人：Herrmann Martina

  公开号：US20100080761A1

  公开（公告）日：2010-04-01

  The present invention relates to extracts of Isochrysis sp., preferably Tahitian Isochrysis, its cosmetic, dermatological and/or therapeutic uses and compositions and cosmetic, dermatological or therapeutic products comprising such an extract of Isochrysis sp., preferably Tahitian Isochrysis.

  本发明涉及Isochrysissp.的提取物，优选为塔希提Isochrysis，及其在化妆品、皮肤病学和/或治疗学上的用途以及包含该Isochrysissp.提取物的化妆品、皮肤病学或治疗学产品，优选为塔希提Isochrysis。
• EXTRACTS OF TETRASELMIS SP.
  申请人：Pertile Paolo

  公开号：US20100143267A1

  公开（公告）日：2010-06-10

  The present invention relates to extracts of Tetraselmis sp., preferably Tetraselmis suecica , its cosmetic, dermatological and/or therapeutic uses and compositions and cosmetic, dermatological or therapeutic products comprising such an extract of Tetraselmis sp., preferably Tetraselmis suecica.

  本发明涉及Tetraselmis sp.的提取物，优选为Tetraselmis suecica，以及其在化妆品、皮肤科和/或治疗用途中的用途、组合物和包含该Tetraselmis sp.提取物的化妆品、皮肤科或治疗产品。
• COMPOUNDS FOR PREVENTING, REDUCING AND/OR ALLEVIATING ITCHY SKIN CONDITION(S)
  申请人：SCHMAUS Gerhard

  公开号：US20160008297A1

  公开（公告）日：2016-01-14

  The present invention primarily relates to the use of one or more specific compounds and/or one or more respective salt(s) thereof for preventing, reducing or alleviating itchy skin condition(s), and/or as PAR-2 antagonist. Furthermore, the present invention relates to compositions (products or, respectively, formulations), in particular for topical administration, preferably cosmetic or pharmaceutical compositions, in particular for preventing, reducing or alleviating one or more itchy skin conditions and/or for providing a PAR-2 antagonistic effect, comprising or consisting of an effect amount of such compound(s) and/or salt(s) and one or more cosmetically and/or pharmaceutically acceptable carriers.

  本发明主要涉及使用一种或多种特定化合物和/或其一个或多个相应盐来预防、减少或缓解瘙痒皮肤状况，和/或作为PAR-2拮抗剂。此外，本发明涉及组合物（产品或相应的配方），特别是用于局部给药，优选为化妆品或药用组合物，特别是用于预防、减少或缓解一种或多种瘙痒皮肤状况和/或产生PAR-2拮抗作用的组合物，包括或由效果量的这种化合物和/或盐以及一个或多个化妆品和/或药用可接受载体组成。
• USE OF DIHYDRODEHYDRODIISOEUGENOL AND PREPARATIONS COMPRISING DIHYDRODEHYDRODIISOEUGENOL
  申请人：Meyer Imke

  公开号：US20130101650A1

  公开（公告）日：2013-04-25

  This invention relates to cosmetic and pharmaceutical preparations comprising (i) a diastereomer or a mixture of two or more diastereomers of the compound of formula (I) or (ii) a salt of a diastereomer or of a mixture of two or more diastereomers of the compound of formula (I) or (iii) a mixture of two or more salts of a diastereomer or of a mixture of two or more diastereomers of the compound of formula (I), a diastereomer, salt or a mixture as defined above as a drug for topical application and/or for the treatment of lipoatrophy; the non-therapeutic use of a diastereomer, salt or a mixture as defined above for the prevention, treatment or reduction of skin aging, especially skin wrinkles; the use of a diastereomer, salt or a mixture as defined above for the production of an orally administered non-pharmaceutical preparation.

  本发明涉及包含(i)化合物的对映异构体或两个或两个以上对映异构体的混合物或(ii)化合物的对映异构体或两个或两个以上对映异构体的混合物的盐或(iii)化合物的对映异构体或两个或两个以上对映异构体的混合物的两个或两个以上盐的混合物的化妆品和药用制剂，上述对映异构体、盐或混合物被定义为用于局部应用的药物和/或治疗脂肪萎缩；上述对映异构体、盐或混合物的非治疗用途被定义为用于预防、治疗或减少皮肤老化，特别是皱纹；上述对映异构体、盐或混合物被定义为用于制造口服非药用制剂。
• USE OF PTEROCARPANS AS ACTIVE ANTI-CELLULITE INGREDIENTS
  申请人：Meyer Imke

  公开号：US20110034486A1

  公开（公告）日：2011-02-10

  The invention relates to a cosmetic, dermatological or pharmaceutical preparation, containing one, two or more compounds of formula (I) and/or a pharmaceutically acceptable salt of a compound of this type, (i) for use in a method for preventing, treating or reducing cellulite, and/or (ii) in an adequate quantity to reduce the lipid quantity contained in subcutaneous fat tissue, and/or to inhibit the differentiation of preadipocytes, and/or to inhibit the lipogenesis in adipocytes, wherein the radicals R1 to R8, independently of one another, signify hydrogen, hydroxy or C1-C4-alkoxy, and/or two adjacent radicals together form a methylenedioxy group.

  该发明涉及一种化妆品、皮肤学或药用制剂，包含一个、两个或更多的式(I)化合物和/或该类型化合物的药用盐，(i)用于预防、治疗或减少脂肪团，和/或(ii)以适量减少皮下脂肪组织中所含的脂质量，和/或抑制脂肪前体细胞的分化，和/或抑制脂肪细胞中的脂肪合成，在该式中，基团R1至R8，彼此独立地表示氢、羟基或C1-C4-烷氧基，和/或两个相邻的基团一起形成亚甲二氧基基团。