methyl β-D-oleandropyranoside | 23568-10-7

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: methyl β-D-oleandropyranoside
• 英文别名: (2R,3R,4R,6R)-4,6-dimethoxy-2-methyloxan-3-ol
• CAS: 23568-10-7
• 化学式: C₈H₁₆O₄
• 分子量: 176.213
• InChiKey: WHDBCFVBMDLPAF-WCTZXXKLSA-N

物化性质

• 沸点：
  256.5±40.0 °C(Predicted)
• 密度：
  1.09±0.1 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  0
• 重原子数：
  12
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  47.9
• 氢给体数：
  1
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  3,5-二异氰酸硝基苯 、 methyl β-D-oleandropyranoside 在 吡啶 作用下， 以 甲苯 为溶剂， 反应 0.5h， 以15.5 mg的产率得到methyl β-D-oleandropyranoside 3,5-dinitrophenylcarbamate
  参考文献：
  名称：

  Tsukamoto, Sachiko; Hayashi, Koji; Kaneko, Ko, Journal of the Chemical Society. Perkin transactions I, 1988, p. 787 - 790

  摘要：

  DOI：
• 作为产物：
  描述：

  D-oleandropyranose 、 甲醇 生成 methyl β-D-oleandropyranoside
  参考文献：
  名称：

  TSUKAMOTO, SACHIKO;HAYASHI, KOJI;KANEKO, KO;MITSUHASHI, HIROSHI, J. CHEM. SOC. PERKIN TRANS.,(1988) N 4, 787-790

  摘要：

  DOI：

文献信息

• Studies on the constituents of Asclepiadaceae plants. L. Two new oligoglycosides, cynanchoside C2 and cynanchoside C1, from Cynanchum caudatum Max..
  作者：KEIJI WADA、KOJI HAYASHI、HIROSHI MITSUHASHI、HIDEO BANDO

  DOI：10.1248/cpb.30.3500

  日期：——

  Two new steroidal oligoglycosides, named cynanchoside C2 (1a) and cyanchoside C1 (2a), were isolated from the rhizome of Cynanchum caudatum MAX. The structures of 1a and 2a were elucidated by the application of 13C-nuclear magnetic resonance spectroscopy and chemical reactions.

  从牛皮消根中分离得到两种新的甾体低聚糖苷，分别命名为牛皮消苷C2（1a）和牛皮消苷C1（2a）。通过应用13C核磁共振波谱和化学反应阐明了1a和2a的结构。
• Indonesian Medicinal Plants. I. Chemical Structures of Calotroposides A and B, Two New Oxypregnane-Oligoglycosides from the Root of Calotropis gigantea (Asclepiadaceae).
  作者：Isao KITAGAWA、Ru-song ZHANG、Jong Dae PARK、Nam In BAEK、Yasuyuki TAKEDA、Masayuki YOSHIKAWA、Hirotaka SHIBUYA

  DOI：10.1248/cpb.40.2007

  日期：——

  Two new oxypregnane-oligoglycosides named calotroposides A (1) and B (2) have been isolated from the root of Calotropis gigantea (Asclepiadaceae), an Indonesian medicinal plant, and their chemical structures have been elucidated by chemical and spectroscopic methods as 12-O-benzoyllineolon 3-O-β-D-cymaropyranosyl(1→4)-β-D-oleandropyranosyl(1→4)-β-D-oleandropyranosyl(1→4)-β-D-cymaropyranosyl(1→4)-β-D-cymaropyranoside and 12-O-benzoylde-acetylmetaplexigenin 3-O-β-D-cymaropyranosyl(1→4)-β-D-oleandropyranosyl(1→4)-β-D-oleandropyranosyl(1→4)-β-D-cymaropyranosyl(1→4)-β-D-cymaropyranoside, respectively.

  从印度尼西亚药用植物Calotropis gigantea（夷果科）的根中分离出两种新型氧孕烷寡糖苷，分别命名为calotroposides A (1) 和B (2)。通过化学和光谱方法阐明了它们的化学结构，分别为12-O-苯甲酰林诺酮 3-O-β-D-醋酸甲酰基(1→4)-β-D-油菜糖基(1→4)-β-D-油菜糖基(1→4)-β-D-醋酸甲酰基(1→4)-β-D-醋酸甲酰基苷和12-O-苯甲酰-去乙酰基甲基生物雌激素 3-O-β-D-醋酸甲酰基(1→4)-β-D-油菜糖基(1→4)-β-D-油菜糖基(1→4)-β-D-醋酸甲酰基(1→4)-β-D-醋酸甲酰基苷。
• Cytotoxicity of pregnane glycosides of Cynanchum otophyllum
  作者：Mi Zhang、Xiang Li、Cheng Xiang、Yi Qin、Jing He、Bao-Cai Li、Peng Li

  DOI：10.1016/j.steroids.2015.08.010

  日期：2015.12

  Fourteen new pregnane glycosides, including nine caudatin glycosides (1-9), three qinyangshengenin glycosides (10-12), one kidjoranin glycosides (13) and one gagaminin glycosides (14), along with twelve known analogs (15-26) were isolated from roots of Cynanchum otophyllum Schneid. Their structures were deduced by detailed analysis of 1D and 2D NMR spectra, as well as HRESIMS. In this study, all pregnane glycosides obtained (1-26) were evaluated for their cytotoxic activities using three cancer cell lines (HepG2, Hela, U251). As results, except 6 and 10, other twenty-four pregnane glycosides showed cytotoxicities at different degrees against three cell lines. (C) 2015 Elsevier Inc. All rights reserved.
• TSUKAMOTO, SACHIKO;HAYASHI, KOJI;KANEKO, KO;MITSUHASHI, HIROSHI, J. CHEM. SOC. PERKIN TRANS.,(1988) N 4, 787-790
  作者：TSUKAMOTO, SACHIKO、HAYASHI, KOJI、KANEKO, KO、MITSUHASHI, HIROSHI

  DOI：——

  日期：——
• Tsukamoto, Sachiko; Hayashi, Koji; Kaneko, Ko, Journal of the Chemical Society. Perkin transactions I, 1988, p. 787 - 790
  作者：Tsukamoto, Sachiko、Hayashi, Koji、Kaneko, Ko、Mitsuhashi, Hiroshi

  DOI：——

  日期：——