O⁴-methyl-α-D-galactopyranose | 31505-25-6

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: O⁴-methyl-α-D-galactopyranose
• 英文别名: (2S,3R,4R,5R,6R)-6-(hydroxymethyl)-5-methoxyoxane-2,3,4-triol
• CAS: 31505-25-6
• 化学式: C₇H₁₄O₆
• 分子量: 194.185
• InChiKey: UGQUOHHDWLIZQM-OVHBTUCOSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -2.6
• 重原子数：
  13
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  99.4
• 氢给体数：
  4
• 氢受体数：
  6

文献信息

• GLYCOMIMETICS TO INHIBIT PATHOGEN-HOST INTERACTIONS
  申请人：The University Of Georgia Research Foundation, Inc

  公开号：EP2825178A1

  公开（公告）日：2015-01-21
• US6245902B1
  申请人：——

  公开号：US6245902B1

  公开（公告）日：2001-06-12
• US9605014B2
  申请人：——

  公开号：US9605014B2

  公开（公告）日：2017-03-28
• [EN] C-GLYCOSIDE ANALOGS AND METHODS FOR THEIR PREPARATION AND USE<br/>[FR] ANALOGUES DE C-CLYCOSIDE ET LEURS PROCEDES DE PREPARATION ET D'UTILISATION
  申请人：UNIV IOWA RES FOUND

  公开号：WO2001010877A1

  公开（公告）日：2001-02-15

  The invention provides versatile sialic acid C-glycoside precursors that are useful for preparing C-glycoside analogs of Gangliosides, peptides, and proteins, as well as synthetic intermediates useful for the preparation of the precursors, and synthetic methods useful for preparing the precursors and the intermediates. The invention also provides gangliosides, peptides, and proteins that comprise sialic acid C-glycoside components, as well as synthetic methods useful for the preparation of such compounds.
• [EN] GLYCOMIMETICS TO INHIBIT PATHOGEN-HOST INTERACTIONS<br/>[FR] GLYCOMIMÉTIQUES POUR INHIBER LES INTERACTIONS PATHOGÈNE-HÔTE
  申请人：UNIV GEOGIA RES FOUNDATION INC

  公开号：WO2013138563A1

  公开（公告）日：2013-09-19

  The present invention relates to novel glycomimetic compounds that are rationally designed to inhibit the binding of various pathogens to cell surface sialylated galactose and methods of use thereof. Specifically sialic acid glycosides and C-glycosides are disclosed that form a lactam ring structure or a cyclic ether/amine ring structure with the adjacent monosaccharide residue.