N-acetyl-L-galactosamine | 149054-75-1

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: N-acetyl-L-galactosamine
• 英文别名: N-[(2S,3S,4S,5S)-3,4,5,6-tetrahydroxy-1-oxohexan-2-yl]acetamide
• CAS: 149054-75-1
• 化学式: C₈H₁₅NO₆
• 分子量: 221.21
• InChiKey: MBLBDJOUHNCFQT-VGRMVHKJSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -3.4
• 重原子数：
  15
• 可旋转键数：
  6
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.75
• 拓扑面积：
  127
• 氢给体数：
  5
• 氢受体数：
  6

文献信息

• Serine protease inhibitor and processes for the preparation thereof
  申请人：——

  公开号：US20030100089A1

  公开（公告）日：2003-05-29

  A composition comprising a protein having an inhibitory activity for a serine protease and, in particular, for a serine elastase, the protein having a molecular weight of about 46 kDa in a deglycosylated form, and having a molecular weight of about 54 kDa when isolated in a glycosylated form is provided. Methods of using the protein in treatments of diseases where inhibition of a serine protease and, in particular, of a serine elastase is effective are provided as well as compositions, reagents, and kits related thereto.

  提供了一种包含对丝氨酸蛋白酶，特别是对丝氨酸弹性蛋白酶具有抑制活性的蛋白质的组合物，该蛋白质在脱糖形式下分子量约为46 kDa，在糖基化形式下分离时分子量约为54 kDa。 提供了将该蛋白质用于治疗丝氨酸蛋白酶，特别是丝氨酸弹性蛋白酶抑制有效的疾病的方法，以及与之相关的组合物、试剂和试剂盒。
• Polysaccharidic esters of n-derivatives of glutamic acid
  申请人：——

  公开号：US20030158125A1

  公开（公告）日：2003-08-21

  The present invention is related to polysaccharide esters of N-derivatives of glutamic acid (N-GA derivatives). These polysaccharidic esters have antiproliferative activity and are characterized by a low systemic toxicity. The esters of the invention are used in the prevention and therapy of diseases caused by cellular hyperproliferation, particularly psoriasis, tumors, rheumatoid arthritis, or intestinal inflammatory pathologies.

  本发明涉及谷氨酸 N-衍生物（N-GA 衍生物）的多糖酯。这些多糖酯具有抗增殖活性，其特点是全身毒性低。本发明的酯类可用于预防和治疗由细胞过度增殖引起的疾病，特别是牛皮癣、肿瘤、类风湿性关节炎或肠道炎症性病变。
• POLYSACCHARIDIC ESTERS OF N-DERIVATIVES OF GLUTAMIC ACID
  申请人：EURAND PHARMACEUTICALS LTD.

  公开号：EP1274446A1

  公开（公告）日：2003-01-15
• COMPOSITION FOR IMPROVING THE APPEARANCE OF AGEING SKIN
  申请人：Merz Pharma GmbH & Co. KGaA

  公开号：EP3131521B1

  公开（公告）日：2020-11-11
• US6844328B2
  申请人：——

  公开号：US6844328B2

  公开（公告）日：2005-01-18