5-ethoxy-3,3-dimethyl-cyclohexanone | 13019-14-2

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 5-ethoxy-3,3-dimethyl-cyclohexanone
• 英文别名: 5-Aethoxy-3,3-dimethyl-cyclohexanon；5-Ethoxy-3,3-dimethylcyclohexanone；5-ethoxy-3,3-dimethylcyclohexan-1-one
• CAS: 13019-14-2
• 化学式: C₁₀H₁₈O₂
• 分子量: 170.252
• InChiKey: SNBSAYUSYXXRJX-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.5
• 重原子数：
  12
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.9
• 拓扑面积：
  26.3
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  alkaline earth salt of/the/ methylsulfuric acid 在 乙醇 、 sodium 作用下， 生成 5-ethoxy-3,3-dimethyl-cyclohexanone
  参考文献：
  名称：

  Successful treatment of hypereosinophilic syndrome in a dog

  摘要：

  An 11‐year‐old crossbred dog was presented with a history of episodic vomiting, diarrhoea, abdominal discomfort and coughing. These signs had been present for several years. Marked peripheral eosinophilia (10.3 × 109/L) was found. No underlying cause of reactive eosinophilia was apparent. Bone marrow aspiration biopsy showed hyperplasia of the eosinophilic cell line, with some increase in immaturity, although all cells were morphologically normal. There were numerous eosinophils in bronchial wash fluid and eosinophilic infiltrates were evident in biopsies of pancreas, liver, small intestine and colon but not stomach. Hypereosinophilic syndrome was diagnosed. The dog responded well to twice daily treatment with hydroxyurea and prednisolone. Clinical signs are well‐controlled 16 months later.

  DOI：

  10.1111/j.1751-0813.2001.tb10671.x

文献信息

• H3PW12O40 encapsulation by nanoporous metal organic framework HKUST-1: Synthesis, characterization, activity and stability
  作者：Ezzat Rafiee、Narges Nobakht

  DOI：10.17344/acsi.2016.2236

  日期：2016.6.15

  potentiometric titration with n-butylamine and PW/HKUST-1 presented very strong acidic sites with Ei > 100 mV. This nano catalyst was successfully used for the synthesis of various β-keto enol ethers at 45 °C with 51-98% yield after 5-75 min. The catalyst was easily recycled and reused at least four times without significant loss of its activity (94% yield after forth run). The presence of the PW in PW/HKUST-1

  通过将H3PW12O40（PW）封装到HKUST-1（Cu3（BTC）2，BTC = 1,3,5-苯三甲酸）中以5 Cu（NO3）2·3H2O / 2.8 BTC的摩尔组成将杂化复合材料制成通过将PW和铜盐的溶液添加到BTC和表面活性剂的混合物中来获得/0.3 PW / 0.6 CTAB。通过多种技术对催化剂进行了表征，包括粉末X射线衍射（XRD），傅立叶变换红外（FT-IR），扫描电子显微镜（SEM），能量色散X射线（EDX），激光粒度分析仪，Brunauer Emmett-柜员（BET）。催化剂的酸度通过正丁胺的电位滴定法测量，PW / HKUST-1表现出非常强的酸性位点，Ei> 100 mV。该纳米催化剂成功地用于在45°C下5-75分钟后以51-98％的产率合成各种β-酮烯醇醚。该催化剂易于回收利用，至少可重复使用四次，而不会显着降低其活性（第四次运行后收率为94％）。PW /
• Successful treatment of hypereosinophilic syndrome in a dog
  作者：MC PERKINS、ADJ WATSON

  DOI：10.1111/j.1751-0813.2001.tb10671.x

  日期：2001.10

  An 11‐year‐old crossbred dog was presented with a history of episodic vomiting, diarrhoea, abdominal discomfort and coughing. These signs had been present for several years. Marked peripheral eosinophilia (10.3 × 109/L) was found. No underlying cause of reactive eosinophilia was apparent. Bone marrow aspiration biopsy showed hyperplasia of the eosinophilic cell line, with some increase in immaturity, although all cells were morphologically normal. There were numerous eosinophils in bronchial wash fluid and eosinophilic infiltrates were evident in biopsies of pancreas, liver, small intestine and colon but not stomach. Hypereosinophilic syndrome was diagnosed. The dog responded well to twice daily treatment with hydroxyurea and prednisolone. Clinical signs are well‐controlled 16 months later.