1,1,1,3,3,3-hexafluoropropan-2-yl acrylate | 24499-62-5

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: 1,1,1,3,3,3-hexafluoropropan-2-yl acrylate
• 英文别名: 1,1,1,3,3,3-hexafluoropropan-2-yl propionate；1,1,1,3,3,3-hexafluoroisopropyl propionate；hexafluoroisopropyl propionate；Propanoic acid 1-(trifluoromethyl)-2,2,2-trifluoroethyl ester；1,1,1,3,3,3-hexafluoropropan-2-yl propanoate
• CAS: 24499-62-5
• 化学式: C₆H₆F₆O₂
• 分子量: 224.103
• InChiKey: OPPLWOJNEKNGAT-UHFFFAOYSA-N

物化性质

• 沸点：
  86-87 °C
• 密度：
  1.364±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  2.9
• 重原子数：
  14
• 可旋转键数：
  3
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.83
• 拓扑面积：
  26.3
• 氢给体数：
  0
• 氢受体数：
  8

反应信息

• 作为反应物：
  描述：

  1,1,1,3,3,3-hexafluoropropan-2-yl acrylate 、 联硼酸频那醇酯 在 copper(II) carbonate 、 三苯基膦 作用下， 以 水 为溶剂， 反应 24.83h， 以82%的产率得到1,1,1,3,3,3-hexafluoro-propan-2-yl 3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)propanoate
  参考文献：
  名称：

  ß-boration of alkene and alkyne intermediates

  摘要：

  这项发明涉及有机化学领域，特别是β-硼化合物的制备。这些β-硼化合物可以用作合成药用活性剂如西他列汀的中间体。

  公开号：

  EP2647639A1
• 作为产物：
  描述：

  1,1,1,3,3,3-六氟异丙基丙烯酸酯 在 [,14-bis(diphenylphosphino)butane] (1,5-cyclooctadiene)rhodium(I) tetrafluoroborate 、 氢气 作用下， 以 氘代甲醇 为溶剂， 反应 0.01h， 生成 1,1,1,3,3,3-hexafluoropropan-2-yl acrylate
  参考文献：
  名称：

  低易燃仲氢偏振 MRI 造影剂

  摘要：

  许多采用仲氢诱导极化 (PHIP) 技术形成的 MRI 造影剂表现出生物相容性。在使用可吸入分子造影剂进行呼吸成像的背景下，不可燃造影剂的开发仍然非常有利于这种敏感、高通量和经济实惠的超极化技术的生物医学转化。为此，我们评估了不同氟取代度下 PHIP 超极化产物（酸、醚和酯）的氢化动力学、极化水平和寿命。结果强调了作为分子结构函数的重要趋势，有助于设计用于 PHIP 技术体内成像应用的新型安全造影剂，重点是用作吸入麻醉剂的高挥发性醚类。

  DOI：

  10.1002/chem.202004168

文献信息

• [EN] FLUORINATED ELECTROLYTE ADDITIVES<br/>[FR] ADDITIFS D'ÉLECTROLYTE FLUORÉ
  申请人：E3TRIGEN INC

  公开号：WO2021055560A1

  公开（公告）日：2021-03-25

  The disclosure relates to the use of fluorinated ethers such as 1,1, 1,3,3,3-hexafluoro-2-methoxypropane (HFMOP) as a reaction solvent to prepare fluorinated dialkyl carbonate and sulfite compounds useful in batteries, and to electrolytes containing fluorinated compounds for use in batteries containing high Ni cathodes and silicon containing anodes.

  该公开涉及使用氟化醚，如1,1,1,3,3,3-六氟-2-甲氧基丙烷（HFMOP）作为反应溶剂，用于制备用于电池的氟化二烷基碳酸酯和亚硫酸盐化合物，并用于含有高镍阴极和含硅阳极的电池中的含氟化合物的电解质。
• Production Processes and Systems, Compositions, Surfactants, Monomer Units, Metal Complexes, Phosphate Esters, Glycols, Aqueous Film Forming Foams, and Foam Stabilizers
  申请人：Jackson Andrew

  公开号：US20090137773A1

  公开（公告）日：2009-05-28

  Compositions and methods for making compositions such as RF(Rτ)nQ are provided. The RF group can include at least two —CF3 groups, the Rτ group can be a group having at least two carbons, n can be at least 1, and the Q group can include one or more atoms of the periodic table of elements. RF-intermediates (RF(RT)nQg); Surfactants (RF(RT)nQs); Foam stabilizers (RF(RT)IIQFS); Metal complexes (RF(RT)IIQMC); Phosphate ester (RF(RT)HQPE); Polymers (RF(RT)IIQMU); Monomers (RF(RT)IIQM); Urethanes (RF(Rτ)nQu); and/or Glycols (RF(RT)IIQH) and methods for making the same are provided.

  本发明提供了制备RF（Rτ）nQ等组合物的方法和组合物。其中，RF基团可以包括至少两个—CF3基团，Rτ基团可以是具有至少两个碳的基团，n可以至少为1，而Q基团可以包括元素周期表中的一个或多个原子。本发明还提供了RF中间体（RF（Rτ）nQg）；表面活性剂（RF（Rτ）nQs）；泡沫稳定剂（RF（Rτ）IIQFS）；金属配合物（RF（Rτ）IIQMC）；磷酸酯（RF（Rτ）HQPE）；聚合物（RF（Rτ）IIQMU）；单体（RF（Rτ）IIQM）；脲（RF（Rτ）nQu）；以及/或者乙二醇（RF（Rτ）IIQH）和制备它们的方法。
• RING-OPENING METATHESIS POLYMERS, PRODUCTS OF HYDROGENATION THEREOF, PROCESS FOR PRODUCTION OF THE SAME AND USES THEREOF
  申请人：Mitsui Chemicals, Inc.

  公开号：EP2045280A1

  公开（公告）日：2009-04-08

  Provided are a ring-opening metathesis polymer and a hydrogenated product thereof that are useful as materials for an optical component, and a method for preparation thereof. The present invention relates to a ring-opening metathesis polymer comprising at least repeating structural units [A] represented by the following General Formula [1] and repeating structural units [B] represented by the following General Formula [2] at a constitutional molar ratio [A]/[B] of 0.1/99.9 to 100/0. The present invention relates to a ring-opening metathesis polymer comprising at least repeating structural units [A] represented by the following General Formula [1] and repeating structural units [B] represented by the following General Formula [2] at a constitutional molar ratio [A]/[B] of 0.1/99.9 to 100/0.

  本发明提供了一种可用作光学元件材料的开环元合成聚合物及其氢化产物，以及制备方法。本发明涉及一种开环元合成聚合物，它至少包含由下式通式[1]表示的重复结构单元[A]和由下式通式[2]表示的重复结构单元[B]，其组成摩尔比[A]/[B]为 0.1/99.9 至 100/0。本发明涉及一种开环嵌段聚合物，它至少包含由下式通式[1]表示的重复结构单元[A]和由下式通式[2]表示的重复结构单元[B]，其组成摩尔比[A]/[B]为 0.1/99.9 至 100/0。
• Insight into the Mechanism and Stereochemistry of the Transformations of Alkyltitanium Ate-Complexes. An Enhanced Enantioselectivity in the Cyclopropanation of the Carboxylic Esters with Titanacyclopropane Reagents
  作者：Oleg G. Kulinkovich、Dzmitry G. Kananovich、Margus Lopp、Victor Snieckus

  DOI：10.1002/adsc.201400480

  日期：2014.11.24

  AbstractThe dependence of the stereoselectivity of the cyclopropanation reaction of γ,γ‐diphenyl‐γ‐butyrolactone and carboxylic esters with alkylmagnesium bromides in the presence of titanium(IV) TADDOLates on the structure of the reactants has been examined in detail. It has been found that the enantioselectivity in the formation of cis‐1,2‐disubstituted cyclopropanols is a function of the structure of the carboxylic ester alkoxy group and leads, in the case of cyclopropanation of hexafluoroisopropyl alkanoates, to 84% ee. To rationalize these observations, as well as the NMR data on the structures of the TADDOL‐derived alkyltitanium species, a new mechanistic model for the formation of the five‐coordinated chiral titanacyclopropane reactive intermediates and their subsequent reorganization in the reactions with esters is proposed. The essential features of this model consist in the generation of configurationally stable TADDOL derived titanacyclopropane species with an apical or equatorial position of the stereogenic carbanion center which is followed by retention or inversion of absolute configuration in course of the displacement of the carboxylic ester alkoxy group.magnified image
• Kim, Yong-Joo; Osakada, Kohtaro; Sugita, Kouji, Organometallics, 1988, vol. 7, # 10, p. 2182 - 2188
  作者：Kim, Yong-Joo、Osakada, Kohtaro、Sugita, Kouji、Yamamoto, Takakazu、Yamamoto, Akio

  DOI：——

  日期：——