2-(4-hydroxyphenyl)ethyl O-β-D-glucopyranosyl-(1→6)-β-D-glucopyranoside | 1382396-87-3

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 2-(4-hydroxyphenyl)ethyl O-β-D-glucopyranosyl-(1→6)-β-D-glucopyranoside
• 英文别名: 2-(4-hydroxyphenyl)ethyl β-D-glucopyranosyl-(1→6)-β-D-glucopyranoside；2-(4-hydroxyphenyl)-ethyl-O-β-D-glucopyranosyl-6-O-β-D-glucopyranoside；Glc(b1-6)Glc(b)-O-EtPh(4-OH)；(2R,3S,4S,5R,6R)-2-(hydroxymethyl)-6-[[(2R,3S,4S,5R,6R)-3,4,5-trihydroxy-6-[2-(4-hydroxyphenyl)ethoxy]oxan-2-yl]methoxy]oxane-3,4,5-triol
• CAS: 1382396-87-3
• 化学式: C₂₀H₃₀O₁₂
• 分子量: 462.451
• InChiKey: SQHAOKVLRGPBHU-XSVWGIRKSA-N

物化性质

• 沸点：
  762.0±60.0 °C(predicted)
• 密度：
  1.59±0.1 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  -2.6
• 重原子数：
  32
• 可旋转键数：
  8
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.7
• 拓扑面积：
  199
• 氢给体数：
  8
• 氢受体数：
  12

反应信息

• 作为反应物：
  描述：

  2-(4-hydroxyphenyl)ethyl O-β-D-glucopyranosyl-(1→6)-β-D-glucopyranoside 在 盐酸 、 水 作用下， 以 1,4-二氧六环 为溶剂， 反应 6.0h， 生成 葡萄糖
  参考文献：
  名称：

  Isolation, identification and antioxidative capacity of water-soluble phenylpropanoid compounds from Rhodiola crenulata

  摘要：

  Six water-soluble phenylpropanoid compounds obtained from Rhodiola crenulata (R. crenulata) were fractionated by high-speed counter-current chromatography (HSCCC), and purified by semi-preparative high-performance liquid chromatography (Semi-prep HPLC). The purities of the six compounds were all above 98.0% and their structures were identified by spectroscopic methods. Among them, a new compound, 2-(4-hydroxyphenyl)-ethyl-O-beta-D-glucopyranosyl-6-O-beta-D-glucopyranoside (1), together with two known phenylpropanoids, p-hydroxyphenacyl-beta-D-glucopyranoside (3) and picein (4) were isolated from R. crenulata for the first time. Meanwhile, the contents of six isolated ingredients from the crude extract of R. crenulata had been simultaneously detected, with satisfactory results. Furthermore, the antioxidant activities of the six compounds were accessed by measuring the radical scavenging activity against 2,2-diphenyl-1-picrylhydrazy (DPPH), and four compounds exhibited potent antioxidative activity. (C) 2012 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.foodchem.2012.04.011

文献信息

• Isolation, identification and antioxidative capacity of water-soluble phenylpropanoid compounds from Rhodiola crenulata
  作者：Danjun Chen、Junting Fan、Peng Wang、Lanying Zhu、Yang Jin、Yan Peng、Shuhu Du

  DOI：10.1016/j.foodchem.2012.04.011

  日期：2012.10

  Six water-soluble phenylpropanoid compounds obtained from Rhodiola crenulata (R. crenulata) were fractionated by high-speed counter-current chromatography (HSCCC), and purified by semi-preparative high-performance liquid chromatography (Semi-prep HPLC). The purities of the six compounds were all above 98.0% and their structures were identified by spectroscopic methods. Among them, a new compound, 2-(4-hydroxyphenyl)-ethyl-O-beta-D-glucopyranosyl-6-O-beta-D-glucopyranoside (1), together with two known phenylpropanoids, p-hydroxyphenacyl-beta-D-glucopyranoside (3) and picein (4) were isolated from R. crenulata for the first time. Meanwhile, the contents of six isolated ingredients from the crude extract of R. crenulata had been simultaneously detected, with satisfactory results. Furthermore, the antioxidant activities of the six compounds were accessed by measuring the radical scavenging activity against 2,2-diphenyl-1-picrylhydrazy (DPPH), and four compounds exhibited potent antioxidative activity. (C) 2012 Elsevier Ltd. All rights reserved.