6-undecanesulfonic acid | 935458-46-1

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 有机磺酸及其衍生物
• 英文名称: 6-undecanesulfonic acid
• 英文别名: Undecane-6-sulfonic acid；undecane-6-sulfonic acid
• CAS: 935458-46-1
• 化学式: C₁₁H₂₄O₃S
• 分子量: 236.376
• InChiKey: GDGVCMDBVLEMOJ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.8
• 重原子数：
  15
• 可旋转键数：
  9
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  62.8
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  6-undecanesulfonic acid 、 原甲酸三甲酯 以4.92 g的产率得到6-undecanesulfonic acid methyl ester
  参考文献：
  名称：

  Foldamers as Reactive Sieves:  Reactivity as a Probe of Conformational Flexibility

  摘要：

  A series of m-phenyleneethynylene (mPE) oligomers modified with a dimethylaminopyridine (DMAP) unit were treated with methyl sulfonates of varying sizes and shapes, and the relative reactivities were measured by UV spectrophotometry. Using a small-molecule DMAP analogue as a reference, each of the methyl sulfonates was shown to react at nearly identical rate. In great contrast, oligomers that are long enough to fold, and hence capable of binding the methyl sulfonate, experience rate enhancements of 18-1600-fold relative to that of the small-molecule analogue, depending on the type of alkyl chain attached to the guest. Three different oligomer lengths were studied, with the longest oligomers exhibiting the fastest rate and greatest substrate specificity. Even large, bulky guests show slightly enhanced methylation rates compared to that with the reference DMAP, which suggests a dynamic nature to the oligomer's binding cavity. Several mechanistic models to describe this behavior are discussed.

  DOI：

  10.1021/ja067670a
• 作为产物：
  描述：

  二正戊基酮 在 过氧乙酸 、 正丁基锂 、 对甲苯磺酸 、 溶剂黄146 作用下， 以 乙醚 、 苯 为溶剂， 反应 2.0h， 生成 6-undecanesulfonic acid
  参考文献：
  名称：

  Foldamers as Reactive Sieves:  Reactivity as a Probe of Conformational Flexibility

  摘要：

  A series of m-phenyleneethynylene (mPE) oligomers modified with a dimethylaminopyridine (DMAP) unit were treated with methyl sulfonates of varying sizes and shapes, and the relative reactivities were measured by UV spectrophotometry. Using a small-molecule DMAP analogue as a reference, each of the methyl sulfonates was shown to react at nearly identical rate. In great contrast, oligomers that are long enough to fold, and hence capable of binding the methyl sulfonate, experience rate enhancements of 18-1600-fold relative to that of the small-molecule analogue, depending on the type of alkyl chain attached to the guest. Three different oligomer lengths were studied, with the longest oligomers exhibiting the fastest rate and greatest substrate specificity. Even large, bulky guests show slightly enhanced methylation rates compared to that with the reference DMAP, which suggests a dynamic nature to the oligomer's binding cavity. Several mechanistic models to describe this behavior are discussed.

  DOI：

  10.1021/ja067670a

文献信息

• Sulfonated Polyethylene
  申请人：University of Florida Research Foundation, Inc.

  公开号：US20160129436A1

  公开（公告）日：2016-05-12

  A sulfonated polyethylene is achieved where a polymethylene backbone with substituted methylene units having one or two sulfonic acid groups or salts of the sulfonic acid groups periodically, quasiperiodically, or quasirandomly separated from each other by unsubstituted methylene units along the polymer backbone. The sulfonated polyethylene is prepared by suspending a sulfonated ester polyethylene in a polar aprotic non-solvent, whereupon the addition of a strong base saponifies the esters with the dissolving of the resulting sulfonated polyethylene having salts of sulfonic acid groups.

  一种磺化聚乙烯被制备出来，其中聚氢化物骨架具有被取代的亚甲基单元，每个亚甲基单元上有一个或两个磺酸基或磺酸基的盐，这些磺酸基或磺酸基的盐沿着聚合物骨架以周期性、准周期性或准随机的方式被未取代的亚甲基单元分开。该磺化聚乙烯是通过将磺化酯基聚乙烯悬浮在极性无水溶剂中制备的，随后加入强碱使酯基皂化，溶解出具有磺酸基盐的磺化聚乙烯。
• ６−ウンデカンスルホン酸誘導体及びこれを有効成分とする医薬並びに抗菌剤
  申请人：財団法人名古屋産業科学研究所

  公开号：JP2002241362A

  公开（公告）日：2002-08-28

  (57)【要約】 （修正有）\n【課題】新規な６−ウンデカンスルホン酸誘導体及びその塩、これらを有効成分とする医薬及び抗菌剤を提供する。\n【解決手段】一般式１\n〔Ｒ１、Ｒ２はＨ、または一体となって各々結合しているＣと共にＣ＝Ｃ結合を形成し、Ｒ３はＨまたは低級アルキル基、ＸはＯまたはＳ、Ｒ４はＨ、低級アルキル基もしくは水酸基の保護基、またはＸＲ４はＲ５と一体となって各々結合しているＳ及びＣと共に５員環を形成し、Ｒ５はＨ、またはＸＲ４と一体となって各々結合しているＳ及びＣと共に５員環を形成し、Ｒ６はＨまたは保護基が付いてもよい水酸基あるいは低級アルコキシ基、またはＲ５と一体となって各々結合しているＣと共にＣ＝Ｃ二重結合を形成する。〕の６−ウンデカンスルホン酸誘導体又はその塩。

  (57) [摘要]（有修改）． [问题]提供新型的6-十一烷磺酸衍生物及其盐类，以及包含这些衍生物作为活性成分的药物和抗菌剂。\通式1 Јn [R1和R2为H或与每个键合的C结合成C=C键，R3为H或低级烷基，X为O或S，R4为H、低级烷基或羟基的保护基，或XR4与R5结合并与每个键合的S和C结合成5元环。R5与XR4结合形成一个五元环，R5与H结合或与S和C各自与XR4结合，R6与H或羟基或可连接保护基的低级烷氧基结合或与C各自与R5结合形成一个C=C双键]。6-十一烷磺酸的 6-十一烷磺酸衍生物或其盐。
• Agricultural-horticultural fungicide
  申请人：KUMIAI CHEMICAL INDUSTRY CO., LTD.

  公开号：EP0238997B1

  公开（公告）日：1990-06-20
• US4742063A
  申请人：——

  公开号：US4742063A

  公开（公告）日：1988-05-03
• US9724686B2
  申请人：——

  公开号：US9724686B2

  公开（公告）日：2017-08-08