(4R,5R,6R)-6-(1,2-dihydroxyethyl)-2,4,5-trihydroxyoxane-2-carboxylic acid | 22893-70-5

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: (4R,5R,6R)-6-(1,2-dihydroxyethyl)-2,4,5-trihydroxyoxane-2-carboxylic acid
• CAS: 22893-70-5；22893-73-8；27766-61-6；76249-76-8；97276-34-1；112574-55-7；123468-25-7；123537-18-8；145375-12-8；146925-79-3；148347-13-1
• 化学式: C₈H₁₄O₈
• 分子量: 238.194
• InChiKey: NNLZBVFSCVTSLA-FYAFMDQFSA-N

物化性质

• 沸点：
  640.5±55.0 °C(predicted)
• 密度：
  1.835±0.06 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  -2.8
• 重原子数：
  16
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.88
• 拓扑面积：
  148
• 氢给体数：
  6
• 氢受体数：
  8

文献信息

• PRODUCTION OF OLIGOSACCHARIDE MIXTURES BY A CELL
  申请人：Inbiose N.V.

  公开号：EP3954769A1

  公开（公告）日：2022-02-16

  The present invention is in the technical field of synthetic biology and metabolic engineering. More particularly, the present invention is in the technical field of fermentation of metabolically engineered cells. The present invention provides a method for the production of a mixture of at least two different oligosaccharides by a cell as well as the purification of at least one of said oligosaccharides from the cultivation. In addition, the present invention provides a method for the production of a mixture of at least two different oligosaccharides by a metabolically engineered cell as well as the purification of at least one of said oligosaccharides from the cultivation.

  本发明属于合成生物学和代谢工程技术领域。更具体地说，本发明属于代谢工程细胞发酵技术领域。本发明提供了一种细胞生产至少两种不同低聚糖混合物的方法，以及从培养物中纯化至少一种所述低聚糖的方法。此外，本发明还提供了一种通过代谢工程细胞生产至少两种不同低聚糖混合物以及从培养物中纯化至少一种所述低聚糖的方法。
• VIABLE BACTERIAL HOST CELL
  申请人：Inbiose N.V.

  公开号：EP4103710A1

  公开（公告）日：2022-12-21
• KDO-FREE PRODUCTION HOSTS FOR OLIGOSACCHARIDE SYNTHESIS
  申请人：Inbiose N.V.

  公开号：EP4103726A1

  公开（公告）日：2022-12-21
• PRODUCTION OF GLYCOSYLATED PRODUCT IN HOST CELLS
  申请人：Inbiose N.V.

  公开号：EP4103727A2

  公开（公告）日：2022-12-21
• GLYCOMINIMIZED BACTERIAL HOST CELLS
  申请人：INBIOSE N.V.

  公开号：US20220403431A1

  公开（公告）日：2022-12-22

  This disclosure is in the technical field of synthetic biology and metabolic engineering. The disclosure provides engineered viable bacteria having a reduced or abolished synthesis of poly-N-acetyl-glucosamine (PNAG), Enterobacterial Common Antigen (ECA), cellulose, colanic acid, core oligosaccharides, Osmoregulated Periplasmic Glucans and Glucosylglycerol (O), glycan, and trebalose. The disclosure further provides methods for the production of bioproduct by the viable bacteria and uses thereof. Furthermore, the disclosure is in the technical field of fermentation of metabolically engineered microorganisms producing bioproduct.