5-(But-3-en-2-yl)-2,2-dimethyl-1,3-dioxane-4,6-dione | 93201-76-4

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 5-(But-3-en-2-yl)-2,2-dimethyl-1,3-dioxane-4,6-dione
• 英文别名: 5-but-3-en-2-yl-2,2-dimethyl-1,3-dioxane-4,6-dione
• CAS: 93201-76-4
• 化学式: C₁₀H₁₄O₄
• 分子量: 198.22
• InChiKey: HRHPRLXLIRVQGH-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.1
• 重原子数：
  14
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.6
• 拓扑面积：
  52.6
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为产物：
  描述：

  乙烯基溴化镁 、 1,3-二噁烷-4,6-二酮,5-亚乙基-2,2-二甲基- 以40%的产率得到
  参考文献：
  名称：

  ZHANG, YONG-MIN;WU, XIAO-PING, ACTA CHIM. SIN., 1984, 42, N 8, 831-834

  摘要：

  DOI：

文献信息

• Method For Producing Alcohol and Carboxylic Acid Having Optical Activity
  申请人：Dekishima Yasumasa

  公开号：US20080233621A1

  公开（公告）日：2008-09-25

  It is an object of the present invention to provide an inexpensive and efficient industrial method for obtaining (S)-2-pentanol, (S)-2-hexanol, 1-methylalkyl malonic acid and 3-methyl carboxylic acid at a high optical purity. The present invention provides a method of producing (S)-2-pentanol or (S)-2-hexanol which comprises allowing certain types of microorganisms or transformed cells, a product obtained by treating said microorganisms or cells, a culture solution of said microorganisms or cells, and/or a crude purified product or purified product of a carbonyl reductase fraction obtained from said microorganisms or cells, to act on 2-pentanone or 2-hexanone.

  本发明的目的是提供一种廉价高效的工业方法，用于高光学纯度地获得(S)-2-戊醇、(S)-2-己醇、1-甲基烷基丙二酸和3-甲基羧酸。本发明提供了一种生产(S)-2-戊醇或(S)-2-己醇的方法，其包括让某些类型的微生物或转化细胞、经处理后得到的产物、上述微生物或细胞的培养液，和/或从上述微生物或细胞中获得的羰基还原酶分数的粗提纯产物或纯化产物作用于2-戊酮或2-己酮。
• PROCESS FOR PRODUCING OPTICALLY ACTIVE ALCOHOL AND CARBOXYLIC ACID
  申请人：API Corporation

  公开号：EP1712630A1

  公开（公告）日：2006-10-18

  It is an object of the present invention to provide an inexpensive and efficient industrial method for obtaining (S)-2-pentanol, (S)-2-hexanol, 1-methylalkyl malonic acid and 3-methyl carboxylic acid at a high optical purity. The present invention provides a method of producing (S)-2-pentanol or (S)-2-hexanol which comprises allowing certain types of microorganisms or transformed cells, a product obtained by treating said microorganisms or cells, a culture solution of said microorganisms or cells, and/or a crude purified product or purified product of a carbonyl reductase fraction obtained from said microorganisms or cells, to act on 2-pentanone or 2-hexanone.

  本发明的目的是提供一种廉价高效的工业方法，以获得高光学纯度的(S)-2-戊醇、(S)-2-己醇、1-甲基烷基丙二酸和3-甲基羧酸。本发明提供了一种生产(S)-2-戊醇或(S)-2-己醇的方法，该方法包括让某些类型的微生物或转化细胞、通过处理所述微生物或细胞获得的产物、所述微生物或细胞的培养液和/或粗提纯产物或从所述微生物或细胞中获得的羰基还原酶部分的提纯产物作用于2-戊酮或2-己酮。
• Method for producing alcohol and carboxylic acid having optical activity
  申请人：API Corporation

  公开号：EP2278014A2

  公开（公告）日：2011-01-26

  The present invention provides a method for producing (R)- or (S)-3-methyl carboxylic acid represented by the following formula (5): wherein R1 represents an alkyl group containing 3 to 5 carbon atoms, and * represents an asymmetric carbon, which comprises decarboxylating (R)- or (S)-1-methylalkyl malonic acid having optical activity represented by the following formula (1) in the presence of a highly polar solvent and/or an additive for promoting decarboxylation: wherein R1 has the same definition as described above, and * represents an asymmetric carbon.

  本发明提供了一种生产下式（5）所代表的(R)-或(S)-3-甲基羧酸的方法： 其中 R1 代表含有 3 至 5 个碳原子的烷基，* 代表不对称碳、 其中包括在高极性溶剂和/或促进脱羧的添加剂存在下，对具有下式（1）所代表的光学活性的(R)-或(S)-1-甲基烷基丙二酸进行脱羧： 其中 R1 具有与上述相同的定义，* 代表不对称碳。