Bis(prop-2-enyl) 2-methylidenepropanedioate | 3377-22-8

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: Bis(prop-2-enyl) 2-methylidenepropanedioate
• CAS: 3377-22-8
• 化学式: C₁₀H₁₂O₄
• 分子量: 196.203
• InChiKey: BZNGGWJYUIIMAN-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.1
• 重原子数：
  14
• 可旋转键数：
  8
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.2
• 拓扑面积：
  52.6
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  Bis(prop-2-enyl) 2-methylidenepropanedioate 在 (S)-5-benzyl-2-(tert-butyl)-6,6-dimethyl-2,5,6,8-tetrahydro-3H-[1,2,4]triazolo[3,4-c][1,4]oxazine 、 zinc dibromide 作用下， 以 四氢呋喃 、 二氯甲烷 、 N,N-二甲基甲酰胺 为溶剂， 反应 4.0h， 生成 (1S,2R,6S)-diallyl 2-(4-methoxyphenyl)-8-oxo-7-oxaspiro[bicyclo[4.2.0]octane-5,1'-cyclohexane]-3,3-dicarboxylate
  参考文献：
  名称：

  N-杂环碳催化对供体-受体环戊二烯的对映选择性（4 + 2）环状

  摘要：

  在这里，我们报告使用N杂环卡宾催化的供体-受体环丁烷和不饱和酰基氟的对映选择性（4 + 2）环化反应。该反应可实现三步合成环己基β-内酯（25个实例），且化学收率（最高≥90％）和立体化学完整性（均> 20：1 dr，最≥97：3 er）。机理研究支持酯烯醇化克莱森重排，而衍生化提供功能化的环己烯和二氢喹啉酮。

  DOI：

  10.1002/anie.201609330
• 作为产物：
  描述：

  丙二酸二烯丙酯 在 马来酸酐 、 copper diacetate 、 溶剂黄146 作用下， 以 paraffin 、 xylene 为溶剂， 反应 2.75h， 生成 Bis(prop-2-enyl) 2-methylidenepropanedioate
  参考文献：
  名称：

  A versatile and convenient multigram synthesis of methylidenemalonic acid diesters

  摘要：

  DOI：

  10.1021/jo00255a038

文献信息

• Manufacture of polymer dispersions and coating compositions derived from them
  申请人：IMPERIAL CHEMICAL INDUSTRIES PLC

  公开号：EP0013478A1

  公开（公告）日：1980-07-23

  Sterically stabilised dispersions of polymer particles of . size 0.1 10 microns in an aqueous medium are obtained by free radical-initiated polymerisation in the aqueous medium of ethylenically unsaturated monomer at a temperature at least 10°C higher than the glass transition temperature of the polymer to be formed, in the presence of steric stabiliser of a block or graft copolymer of defined characteristics, the aqua- lous medium being one which is capable of dissolving the monomer to the extent of at least 3% by weight but which is a non-solvent for the polymer formed, the conditions being such that at no time is there present a separate phase of free monomer and the resulting dispersion containing at least 20% by weight of polymer. The dispersions can be formulated into aqueous coating compositions having improved properties.

  尺寸为 0.1 10 微米的聚合物颗粒在水介质中的立体稳定分散体，是由乙烯不饱和单体在水介质中进行自由基引发的聚合反应获得的，聚合反应的温度至少要比要形成的聚合物的玻璃化温度高 10°C，聚合反应中要有立体稳定剂存在，立体稳定剂是具有规定特性的嵌段或接枝共聚物、含水介质能够溶解单体，溶解度至少为 3%（按重量计），但对所形成的聚合物不 是溶剂，条件是在任何时候都不存在独立的游离单体相，所得到的分散体至少含有 20% （按重量计）的聚合物。分散体可配制成具有更好性能的水性涂料组合物。
• DE, KEYSER JEAN-LUC;DE, COCK CHRISTIAN J. C.;POUPAERT, JACQUES H.;DUMONT,+, J. ORG. CHEM., 53,(1988) N 20, C. 4859-4862
  作者：DE, KEYSER JEAN-LUC、DE, COCK CHRISTIAN J. C.、POUPAERT, JACQUES H.、DUMONT,+

  DOI：——

  日期：——
• Naphthalenmethylenemalonic diesters, and UV absorbers and cosmetic compositions containing the diesters
  申请人：Kao Corporation

  公开号：EP0663206B1

  公开（公告）日：1999-07-14
• SUBSTITUIERTE AMINOALKOHOLE ALS CHIRALE DOTANDEN
  申请人：FRAUNHOFER-GESELLSCHAFT zur Förderung der angewandten Forschung e.V.

  公开号：EP2766450A1

  公开（公告）日：2014-08-20
• SUBSTITUTED AMINO ALCOHOLS AS CHIRAL DOPANTS
  申请人：Fraunhofer-Gesellschaft zur Förderung der Angewandten Forschung E.V.

  公开号：US20140228591A1

  公开（公告）日：2014-08-14

  The invention relates to the use of a substituted, chiral amino alcohol, comprising one or more structural units of the following formula (1), wherein the abbreviations A, Y, R1 and R3 to R5 have the following meanings: is a covalent bond or a hydrocarbon group, Y is a covalent bond or a hydrocarbon group that can have an oxygen atom at one of its ends through which it is bonded to R 1 , R 1 is an aliphatic or heterocyclic or aromatic radical, the carbon chain of which may be interrupted by one or more B groups, R 5 is selected from the group consisting of (a) aliphatic radicals, wherein individual carbon atoms may be replaced by oxygen atoms or carbonyl groups, and wherein the carbon chains of same radicals may be optionally interrupted by a B group, and (b) araliphatic, cycloaliphatic, aromatic and heterocyclic radicals, wherein the carbon chain can be interrupted by one or more B structural elements and/or by one or more D coupling groups, R 3 , R 4 are hydrogen or aliphatic or araliphatic substituents, which are independent of one another, wherein the carbon chain can be interrupted by one or more B groups, B is selected from polymerizable or crosslinkable structural elements from the group comprising C 1 -C 16 -alkenyl, C 1 -C 16 -alkenyloxy, —C═C—, —CH═CH—COO—, —CH═CH—, —CX═CH—COO— with X═C 1 -C 16 -alkyl, and the trans-form of —OOC—CH═CH—COO—, and D is selected from —O—, —NH—, —N(CH 3 )—, —N(C 2 H 5 )—, —SO 2 —, —CO—, —COO—, —CH═CH—, —OCOO—, —OCH 2 —, CH═N, —CF 2 CF 2 —, as a chiral dopant in liquid crystal (mixtures), e.g., in electro-optical systems.