Thiazolium, 3-[2-[4-(diethylamino)phenyl]-2-oxoethyl]- | 628687-46-7

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: Thiazolium, 3-[2-[4-(diethylamino)phenyl]-2-oxoethyl]-
• 英文别名: 1-[4-(diethylamino)phenyl]-2-(1,3-thiazol-3-ium-3-yl)ethanone
• CAS: 628687-46-7
• 化学式: C15H19N2OS+
• 分子量: 275.4
• InChiKey: WQLSSFPUILJGFD-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.5
• 重原子数：
  19
• 可旋转键数：
  6
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.33
• 拓扑面积：
  52.4
• 氢给体数：
  0
• 氢受体数：
  3

文献信息

• Sunscreen compositions and methods of use thereof
  申请人：——

  公开号：US20040120905A1

  公开（公告）日：2004-06-24

  Disclosed herein are novel methods for reducing or preventing the harmful effects of solar radiation on skin. Also disclosed are novel sunscreen compositions comprising thaizolium, thiadiazolium or triazolium compounds or derivatives and analogs thereof for reducing or preventing the harmful effects of solar radiation on skin. Sunscreen active agents that provide UV-A and UV-B filters are also included. The invention further discloses additional sunscreen active agents, emollients, humectants, dry-feel modifiers, waterproofing agents, insect repellants, antimicrobial preservatives, antioxidants, chelating agents, fragrances and moisturizers, suitable carriers for topical application and emulsions.

  本文公开了用于减少或防止太阳辐射对皮肤有害影响的新型方法。还公开了包含噻唑、噻二唑或三唑化合物或衍生物及其类似物的新型防晒组合物，用于减少或防止太阳辐射对皮肤的有害影响。还包括提供紫外线-A 和紫外线-B 过滤的防晒活性剂。本发明进一步公开了其他防晒活性剂、润肤剂、保湿剂、干感调节剂、防水剂、驱虫剂、抗菌防腐剂、抗氧化剂、螯合剂、香料和保湿剂、适合局部应用的载体和乳液。
• USE OF THIAZOLIUM COMPOUNDS FOR PREVENTING AND REVERSING THE FORMATION OF ADVANCED GLYCOSYLATION ENDPRODUCTS
  申请人：ALTEON Inc.

  公开号：EP0808163B1

  公开（公告）日：2003-07-23
• VITAMIN D PROMOTING SUNSCREEN
  申请人：Armstrong, Ernest T.

  公开号：EP2384193A2

  公开（公告）日：2011-11-09
• VITAMIN D FORMING SUNSCREEN
  申请人：Armstrong Ernest T.

  公开号：US20110268678A1

  公开（公告）日：2011-11-03

  A composition suitable for providing protection against ultraviolet radiation containing one or more active ultraviolet radiation absorber through which ultraviolet radiation in approximately the 295 to 315 nanometer range is permitted to enter the skin in an amount sufficient for the body to produce a healthful and disease-opposing quantity of vitamin D 3 and chemical precursors thereof. The composition is particularly used in sunscreens promoting on the one hand vitamin D 3 production, on the other hand protecting the skin against harmful ultraviolet radiation.
• US6007865A
  申请人：——

  公开号：US6007865A

  公开（公告）日：1999-12-28