alpha-L-Thevetose | 911455-52-2

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: alpha-L-Thevetose
• 英文别名: (2R,3S,4R,5S,6S)-4-methoxy-6-methyloxane-2,3,5-triol
• CAS: 911455-52-2
• 化学式: C₇H₁₄O₅
• 分子量: 178.18
• InChiKey: OEKPKBBXXDGXNB-YPPKRKOXSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -1.6
• 重原子数：
  12
• 可旋转键数：
  1
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  79.2
• 氢给体数：
  3
• 氢受体数：
  5

文献信息

• [EN] COMPOSITIONS AND METHODS FOR THE TREATMENT OF BACTERIAL INFECTIONS<br/>[FR] COMPOSÉS ET MÉTHODES POUR LE TRAITEMENT D'INFECTIONS BACTÉRIENNES
  申请人：CIDARA THERAPEUTICS INC

  公开号：WO2018006063A1

  公开（公告）日：2018-01-04

  Compositions and methods for the treatment of bacterial infections include compounds containing dimers of cyclic heptapeptides conjugated to one or more monosaccharide or oligosaccharide moieties. In particular, compounds can be used in the treatment of bacterial infections caused by Gram-negative bacteria.

  用于治疗细菌感染的组合物和方法包括含有环七肽二聚体与一个或多个单糖或寡糖基团结合的化合物。特别是，这些化合物可用于治疗由革兰氏阴性细菌引起的细菌感染。
• Pharmaceutical compositions having appetite suppressant activity
  申请人：CSIR

  公开号：US20020168427A1

  公开（公告）日：2002-11-14

  A pharmaceutical composition contains an extract obtainable from a plant of the genus Trichocaulon or Hoodia containing an appetite suppressant agent having the formula (1). A process for obtaining the extract and a process for synthesizing compound (1) and its analogues and derivatives is also provided. The invention also extends to the use of such extracts and compound (1) and its analogues for the manufacture of medicaments having appetite suppressant activity. The invention further provides novel intermediates for the synthesis of compound (1).

  一种药物组合物包含可从Trichocaulon或Hoodia属植物中获得的提取物，其中包含具有式（1）的食欲抑制剂。还提供了获得该提取物的过程以及合成化合物（1）及其类似物和衍生物的过程。该发明还扩展到利用这些提取物和化合物（1）及其类似物制造具有食欲抑制活性的药物。该发明还提供了合成化合物（1）的新型中间体。
• DEVICE FOR AUTOMATED SYNTHESIS OF OLIGO- AND POLYSACCHARIDES
  申请人：Max-Planck-Gesellschat zu rFérderung der Wissenschaften e.V.

  公开号：US20220395800A1

  公开（公告）日：2022-12-15

  The present invention generally relates to automated synthesis technology, and more particularly, to a device and method for automated synthesis of oligo- and polysaccharides on a solid support. In particular the present invention relates to a device for automated synthesis of oligo- and polysaccharides on a solid support comprising a reaction vessel, a reagent storing component, a reagent delivery system, a cooling device for cooling reaction vessel, and a pre-cooling device for pre-cooling the reagents to be supplied.

  本发明通常涉及自动合成技术，更具体地，涉及一种用于在固体支持上自动合成寡糖和多糖的装置和方法。特别是，本发明涉及一种用于在固体支持上自动合成寡糖和多糖的装置，包括反应容器、试剂储存组件、试剂输送系统、冷却装置用于冷却反应容器和预冷装置用于预冷待供应试剂的组成部分。
• Isobufalin and isoresibufogenin compounds and methods of preparing the same
  申请人：Advance Biofactures Corporation

  公开号：EP0071460A1

  公开（公告）日：1983-02-09

  This invention relates to novel isomers of naturally occurring cardiotonic compounds, specifically novel isobufalins and novel isoresibufogenins having one of the general formulae and in which R is selected from and A is hydrogen or a monovalent sugar residue. A novel method of preparing these compounds is also disclosed.

  本发明涉及天然强心化合物的新型异构体，特别是具有通式之一且其中 R 选自和 A 选自氢或一价糖残基的新型异蟾蜍苷元和新型异蟾蜍苷元。 本发明还公开了制备这些化合物的新型方法。
• Use of extracts from Hoodia gordonii and Hoodia lugardii for the preparation of a medicament for use in the suppression of appetite
  申请人：CSIR

  公开号：EP1438965A1

  公开（公告）日：2004-07-21

  Extracts obtainable from Hoodia gordonii or lugardii containing an appetite suppressant agent having the formula (1) are disclosed for the manufacture of medicaments having appetite suppressant activity.

  公开了从 Hoodia gordonii 或 lugardii 中提取的含有式（1）食欲抑制剂的提取物，用于制造具有食欲抑制活性的药物。