2,6-bis (phenylglyoxalyl) pyridine | 67534-57-0

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 2,6-bis (phenylglyoxalyl) pyridine
• 英文别名: 1,1'-(Pyridine-2,6-diyl)bis(phenylethane-1,2-dione)；1-[6-(2-oxo-2-phenylacetyl)pyridin-2-yl]-2-phenylethane-1,2-dione
• CAS: 67534-57-0
• 化学式: C₂₁H₁₃NO₄
• 分子量: 343.339
• InChiKey: DZAIHRYPOZQLKM-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.5
• 重原子数：
  26
• 可旋转键数：
  6
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  81.2
• 氢给体数：
  0
• 氢受体数：
  5

反应信息

• 作为反应物：
  描述：

  2,6-bis (phenylglyoxalyl) pyridine 、 二苄基甲酮 在 氢氧化钾 、 乙酸酐 、 氢气 作用下， 生成 3-[6-(3-Oxo-2,4,5-triphenylcyclopenta-1,4-dien-1-yl)pyridin-2-yl]-2,4,5-triphenylcyclopenta-2,4-dien-1-one
  参考文献：
  名称：

  Albatrossidine: A large, easily synthesized molecular cleft

  摘要：

  2,6-Bis(heptaphenyl-2-naphthyl)pyridine (1) was prepared in three steps from 2,6-bis(phenylethynyl)pyridine. and its X-ray structure was determined. The pyridine nitrogen lies at the base of a broad, chiral molecular cleft created by the perphenylnaphthyl ''wings'' of 1. Copyright (C) 1996 Elsevier Science Ltd

  DOI：

  10.1016/s0040-4039(96)02261-7
• 作为产物：
  描述：

  2,6-bis(2-phenylethynyl)pyridine 在 N-溴代丁二酰亚胺(NBS) 、 二甲基亚砜 作用下， 以49%的产率得到2,6-bis (phenylglyoxalyl) pyridine
  参考文献：
  名称：

  Albatrossidine: A large, easily synthesized molecular cleft

  摘要：

  2,6-Bis(heptaphenyl-2-naphthyl)pyridine (1) was prepared in three steps from 2,6-bis(phenylethynyl)pyridine. and its X-ray structure was determined. The pyridine nitrogen lies at the base of a broad, chiral molecular cleft created by the perphenylnaphthyl ''wings'' of 1. Copyright (C) 1996 Elsevier Science Ltd

  DOI：

  10.1016/s0040-4039(96)02261-7

文献信息

• Preparation of tetraketones
  申请人：Wright State University

  公开号：US04082806A1

  公开（公告）日：1978-04-04

  A method of preparing tetraketone precursors which are useful in the production of high temperature resistant polyquinoxaline resins. Suitable diketones are oxidized with a halogenating agent, such as cupric halide or hydrogen bromide, and dimethylsulfoxide to produce the corresponding tetraketone. The tetraketones which can be produced by the instant process have the formula: ##STR1## wherein R is hydrogen or an aryl, substituted aryl, heterocyclic or substituted heterocyclic radical and R' is an aryl, substituted aryl, arylalkyl, arylether, arylthioether, arylsulfoxide, arylsulfone, heterocyclic or substituted heterocyclic radical.

  一种制备四酮前体的方法，这些前体在生产高温耐磨聚喹噁唑树脂中很有用。适当的二酮通过氯化剂（如氯化铜或溴化氢）和二甲基亚砜氧化，产生相应的四酮。通过这种方法可以生产的四酮具有如下结构式：##STR1## 其中R为氢或芳基、取代芳基、杂环或取代杂环基，R'为芳基、取代芳基、芳基烷基、芳基醚、芳基硫醚、芳基亚砜、芳基砜醚、杂环或取代杂环基。
• DMSO–PdI2 as a powerful oxidizing couple of alkynes into benzils: one-pot synthesis of nitrogen-containing five- or six-membered heterocycles
  作者：Céline Mousset、Olivier Provot、Abdallah Hamze、Jérôme Bignon、Jean-Daniel Brion、Mouâd Alami

  DOI：10.1016/j.tet.2008.02.081

  日期：2008.5

  PdI2 in DMSO promoted the oxidation of functionalized diarylalkynes into benzil derivatives in excellent yields. This new oxidation reaction was achieved with short reaction times and low loading of palladium catalyst. This efficient catalytic process has been applied successfully to the one-pot construction of a series of nitrogen-containing heterocycles of biological interest according to a tandem oxidation-nitrogen nucleophiles condensation-cyclization. (c) 2008 Elsevier Ltd. All rights reserved.
• US4082806A
  申请人：——

  公开号：US4082806A

  公开（公告）日：1978-04-04