(E)-2-methyl-2-decenal | 119711-60-3

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: (E)-2-methyl-2-decenal
• 英文别名: (2E)-2-methyl-2-decenal；(E)-2-methyldec-2-enal
• CAS: 119711-60-3
• 化学式: C₁₁H₂₀O
• 分子量: 168.279
• InChiKey: QTXNUCRSDPAMSK-PKNBQFBNSA-N

物化性质

• 沸点：
  243.9±9.0 °C(Predicted)
• 密度：
  0.837±0.06 g/cm3(Predicted)
• 保留指数：
  1325

计算性质

• 辛醇/水分配系数(LogP)：
  4.1
• 重原子数：
  12
• 可旋转键数：
  7
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.73
• 拓扑面积：
  17.1
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  (E)-2-methyl-2-decenal 在 manganese(IV) oxide 、 Bakers'yeast 作用下， 生成 (S)-(-)-2-methyl-1-decanol
  参考文献：
  名称：

  Bakers' yeast reduction of thiophenepropaenals. Enantioselective synthesis of (S)-2-methyl-1-alkanols via bakers' yeast mediated reduction of 2-methyl-3-(2-thiophene)propenals

  摘要：

  DOI：

  10.1021/jo00033a028
• 作为产物：
  描述：

  N,N-dimethyl-N'-(2-methyl-dec-2-enylidene)-hydrazine 在 盐酸 、 水 作用下， 以 Petroleum ether 为溶剂， 反应 7.0h， 生成 (E)-2-methyl-2-decenal
  参考文献：
  名称：

  醛和酮的双碳同系化为 α,β-不饱和醛。

  摘要：

  膦酸酯试剂被开发用于醛或酮的双碳同系化为未支化或甲基支化的 α,β-不饱和醛。膦酸酯试剂，二乙基甲基甲酰基-2-膦酸酯二甲基腙和二乙基乙基甲酰基-2-膦酸酯二甲基腙，含有受保护的醛基而不是通常的酯基。同系化循环需要将试剂与起始醛缩合，然后用 1 M HCl 和石油醚的双相混合物去除二甲基腙保护基团。这种稳健的两步法适用于各种醛和酮。在缩合和脱保护步骤后，不饱和醛产物的总分离产率为 71% 至 86%。

  DOI：

  10.3390/molecules16065062

文献信息

• CATALYST FOR ASYMMETRIC HYDROGENATION AND METHOD FOR MANUFACTURING OPTICALLY ACTIVE CARBONYL COMPOUND USING THE SAME
  申请人：YAMADA Shinya

  公开号：US20120136176A1

  公开（公告）日：2012-05-31

  The present invention provides a catalyst used for manufacturing an optically active carbonyl compound by selective asymmetric hydrogenation of an α,β-unsaturated carbonyl compound, which is insoluble in a reaction mixture, and a method for manufacturing the corresponding optically active carbonyl compound. Particularly, the invention provides a catalyst for obtaining an optically active citronellal useful as a flavor or fragrance, by selective asymmetric hydrogenation of citral, geranial or neral. The invention relates to a catalyst for asymmetric hydrogenation of an α,β-unsaturated carbonyl compound, which comprises: a powder of at least one metal selected from metals belonging to Group 8 to Group 10 of the Periodic Table, or a metal-supported substance in which the at least one metal is supported on a support; an optically active peptide compound; and an acid, and also relates to a method for manufacturing an optically active carbonyl compound using the same.

  本发明提供了一种用于通过选择性不对称加氢α，β-不饱和羰基化合物制备光学活性羰基化合物的催化剂，该催化剂在反应混合物中不溶解，并提供了制备相应光学活性羰基化合物的方法。特别地，该发明提供了一种催化剂，通过选择性不对称加氢柠檬醛、香叶醛或柠檬醛制备出用作香料或芳香剂的光学活性香茅醛。该发明涉及一种用于不对称加氢α，β-不饱和羰基化合物的催化剂，包括：来自周期表第8至第10族金属中至少一种金属的粉末，或者至少一种金属负载物质，其中至少一种金属负载在一种载体上；一种光学活性肽化合物；和一种酸，还涉及使用该催化剂制备光学活性羰基化合物的方法。
• CATALYST FOR ASYMMETRIC HYDROGENATION
  申请人：MAEDA Hironori

  公开号：US20100324338A1

  公开（公告）日：2010-12-23

  This invention aims at providing a catalyst for producing an optically active aldehyde or an optically active ketone, which is an optically active carbonyl compound, by carrying out selective asymmetric hydrogenation of an α,β-unsaturated carbonyl compound, particularly a catalyst which is insoluble in a reaction mixture for obtaining optically active citronellal which is useful as a flavor or fragrance, by carrying out selective asymmetric hydrogenation of citral, geranial or neral; and a method for producing a corresponding optically active carbonyl compound. The invention relates to a catalyst for asymmetric hydrogenation of an α,β-unsaturated carbonyl compound, which comprises a powder of at least one metal selected from metals belonging to Group 8 to Group 10 of the Periodic Table, or a metal-supported substance in which at least one metal selected from metals belonging to Group 8 to Group 10 of the Periodic Table is supported on a support, an optically active cyclic nitrogen-containing compound and an acid.

  这项发明旨在通过对α，β-不饱和羰基化合物进行选择性不对称加氢，特别是通过对柠檬醛、香叶醛或柠檬醛进行选择性不对称加氢，从而提供用作香料或香精的有用的光学活性香茅醛的催化剂，该香茅醛是一种光学活性羰基化合物；以及生产相应的光学活性羰基化合物的方法。该发明涉及一种用于不对称加氢α，β-不饱和羰基化合物的催化剂，其包括来自周期表第8至第10族金属中至少一种金属的粉末，或者至少一种来自周期表第8至第10族金属的金属负载物质，该金属负载在一种支撑物上，还包括光学活性的含氮环化合物和酸。
• PROCESS FOR PRODUCING ALPHA, BETA-UNSATURATED ALDEHYDE COMPOUNDS
  申请人：Ishida Kosaku

  公开号：US20090171124A1

  公开（公告）日：2009-07-02

  The present invention relates to processes for producing α,β-unsaturated aldehyde compounds and unsaturated alcohols with a good yield. There is provided a process for producing and α,β-unsaturated aldehyde compound including the step of subjecting a raw aldehyde compound to an intermolecular condensation reaction in the presence of an amine and a protonic acid having 4 to 20 carbon atoms or a salt thereof; and a process for producing an unsaturated alcohol including the step of subjecting the α,β-unsaturated aldehyde compound to a reduction reaction.

  本发明涉及一种生产α，β-不饱和醛化合物和不饱和醇的工艺，其产率高。提供了一种生产α，β-不饱和醛化合物的工艺，包括在胺和具有4到20个碳原子的质子酸或其盐的存在下，使原始醛化合物经历一种分子间缩合反应的步骤；以及一种生产不饱和醇的工艺，包括使α，β-不饱和醛化合物经历还原反应的步骤。
• Process for preparing pyridine-2,3-dicarboxylic acid compounds
  申请人：SUGAI CHEMICAL INDUSTRY CO., LTD.

  公开号：EP0274379A2

  公开（公告）日：1988-07-13

  A process for preparing pyridine-2,3-dicarboxylic acid compounds of the following formula:     wherein R¹ and R³ are, identical or different, each a hydrogen atom or a lower alkyl group, R² is a hydrogen atom, a lower alkyl group, or a phenyl-(lower)alkyl group which may have halogen atom or lower alkyl group on its phenyl ring, and R⁴ and R⁵ are, identical or different, each a lower alkoxy group. The compounds are useful as an intermediate for preparing agricultural chemicals and pharmaceuticals.

  一种制备下式吡啶-2,3-二羧酸化合物的工艺：其中 R¹ 和 R³ 相同或不同，各为氢原子或低级烷基；R² 为氢原子、低级烷基或苯基（低级）烷基，其苯基环上可能含有卤素原子或低级烷基；R⁴ 和 R⁵ 相同或不同，各为低级烷氧基。 该化合物可用作制备农药和药物的中间体。
• A highly selective method for the synthesis of(E)-α-methyl-α,β-unsaturated aldehydes
  作者：R. Desmond、S.G. Mills、R.P. Volante、I. Shinkai

  DOI：10.1016/s0040-4039(00)80374-3

  日期：1988.1