1-(n-heptyl)-2-aminoethanol | 72799-63-4

• 物质功能分类: 生物化工 - 氨基酸及其衍生物
• 分子结构分类: 有机化合物 - 有机氮化合物
• 英文名称: 1-(n-heptyl)-2-aminoethanol
• 英文别名: 1-Amino-nonan-2-ol；1-aminononan-2-ol
• CAS: 72799-63-4
• 化学式: C₉H₂₁NO
• 分子量: 159.272
• InChiKey: YOANQJMZPGJXJC-UHFFFAOYSA-N

物化性质

• 沸点：
  268.6±13.0 °C(Predicted)
• 密度：
  0.891±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  2.1
• 重原子数：
  11
• 可旋转键数：
  7
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  46.2
• 氢给体数：
  2
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  γ-N,N,N-trimethylammonium butyroxy succinimide iodide 、 1-(n-heptyl)-2-aminoethanol 以 甲醇 为溶剂， 以47%的产率得到neocomplanine B
  参考文献：
  名称：

  Neocomplanines A and B, a Complanine Family Isolated from the Marine Fireworm

  摘要：

  Two new members of the complanine family, neocomplanines A (2) and B (3), were isolated as minor components of the methanolic extract of the "marine fireworm" Eurythoe complanata. The structures of the neocomplanines were revealed spectroscopically to be a trimethylammonium unit with a saturated carbon chain. The planar structures of neocomplanines A and B were confirmed successfully through total syntheses that used epichlorohydrin as a starting material. The neocomplanines show inflammatory activity and also enhanced PKC activity in combination with TPA in the presence of Ca(2+) in vitro; both arc similar to the effects of complanine (1). The molecular mechanism of the effects of complanine-related compounds is discussed.

  DOI：

  10.1021/np900694j
• 作为产物：
  描述：

  2-((trimethylsilyl)oxy)nonanenitrile 在 B2H6-THF 作用下， 以74.4%的产率得到1-(n-heptyl)-2-aminoethanol
  参考文献：
  名称：

  Montmorillonite-K10 Catalyzed Addition OF Trimethylsilylcyanide (TMSCN) to Aldehydes.

  摘要：

  Addition of trimethylsilyl cyanide (TMSCN) to aldehydes was catalyzed by Montmorillonite-K10, with subsequent reduction to beta-aminoalcohol.In recent years we have explored a number of methodologies for the preparation of beta-aminoalcohols(1-4), many of which are biologically active and are also versatile intermediates in organic synthesis as highlighted in a recent review article(5).A convenient route to these beta-aminoalcohols, is the addition of trimethylsilyl cyanide (TMSCN) to an aldehyde or ketone in the presence of a Lewis acid catalyst(6) and subsequent hydride reductions(7,8) to beta-aminoalcohol. Many different Lewis acid catalysts, such as Znl(2), AlCl3, BF3, and Ti(OiPr)(4), have been employed in this reaction. The drawback of this protocol is that the Lewis acid is soluble in the reaction media and very often the final silyloxycyanide is recovered from the reaction mixture by a short path vacuum distillation.

  DOI：

  10.1080/00397919808007179

文献信息

• LUBRICATING OIL COMPOSITION, AND SLIDING MECHANISM USING LUBRICATING OIL COMPOSITION
  申请人：Idemitsu Kosan Co., Ltd

  公开号：EP2826845A1

  公开（公告）日：2015-01-21

  Disclosed is a lubricating oil composition for low-friction sliding materials, which is used in a sliding mechanism where a DLC film containing hydrogen in an amount of from 5 atom% to 50 atom% is formed on at least one sliding surface. The lubricating oil composition contains, in the lubricant base oil therein and based on the total amount of the composition, (A) an organic zinc dithiophosphate in an amount of from 0.005% by mass to 0.12% by mass in terms of the phosphorus concentration therein, (B) an amine-based friction-reducing agent in an amount of from 0.05% by mass to 5.0% by mass, and (C) an alkaline earth metal salicylate-based detergent and/or an alkaline earth metal sulfonate-based detergent in an amount of from 0.05% by mass to 0.5% by mass in terms of the alkaline earth metal concentration therein, wherein the component (A) contains, based on the total amount of the composition, a zinc primary dialkyldithiophosphate in an amount of from 0.005% by mass to 0.05% by mass in terms of the phosphorus concentration therein.

  本发明公开了一种用于低摩擦滑动材料的润滑油组合物，该组合物用于在至少一个滑动表面上形成含氢量为 5 原子％至 50 原子％的 DLC 膜的滑动机构中。该润滑油组合物在其中的润滑油基础油中，根据组合物的总量，含有 (A) 有机二硫代磷酸锌，以其中的磷浓度计，含量为 0.005% （质量百分比）至 0.12% （质量百分比）；(B) 基于胺的减摩剂，含量为 0.05% （质量百分比）至 5.(C) 碱土金属水杨酸酯类洗涤剂和/或碱土金属磺酸盐类洗涤剂，以其中碱土金属的浓度计，其用量为 0.05% (质量) 至 0.5% (质量)，其中组分 (A) 含有以组合物总量计，以其中磷的浓度计，其用量为 0.005% (质量) 至 0.05% (质量)的伯基二烷基二硫代磷酸锌。
• LUBRICANT OIL COMPOSITION
  申请人：Idemitsu Kosan Co., Ltd

  公开号：EP3115444A1

  公开（公告）日：2017-01-11

  Provided is a lubricating oil composition favorable for reducing friction in a sliding mechanism equipped with a piston ring and a liner, in a device having the sliding mechanism. The lubricating oil composition contains a lubricant base oil, (1) a polymethacrylate and/or an olefin copolymer having a mass-average molecular weight of 100,000 to 600,000, and (2) an ester-type ashless friction modifier and/or an amine-type ashless friction modifier, and has a shear viscosity at 150°C of 2.3 mPa· or more and less than 3.7 mPa·s.

  本文提供了一种润滑油组合物，该组合物有利于在具有滑动机构的设备中减少装有活塞环和衬垫的滑动机构的摩擦。该润滑油组合物包含润滑油基础油、(1) 聚甲基丙烯酸酯和/或烯烃共聚物，其质量平均分子量为 100,000 至 600,000，以及 (2) 酯类无灰摩擦改进剂和/或胺类无灰摩擦改进剂，并且在 150°C 时的剪切粘度为 2.3 mPa- 或以上且小于 3.7 mPa-s。
• Importance of the aromatic ring in adrenergic amines. 5. Nonaromatic analogs of phenylethanolamine as inhibitors of phenylethanolamine N-methyltransferase: role of hydrophobic and steric interactions
  作者：William C. Vincek、Constance S. Aldrich、Ronald T. Borchardt、Gary L. Grunewald

  DOI：10.1021/jm00133a003

  日期：1981.1
• Isoquinoline derivatives
  申请人：Asahi Kasei Kogyo Kabushiki Kaisha

  公开号：EP0287696B1

  公开（公告）日：1991-01-02
• US9593291B2
  申请人：——

  公开号：US9593291B2

  公开（公告）日：2017-03-14