3,4-dioxybenzylamine | 94099-46-4

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: 3,4-dioxybenzylamine
• 英文别名: 4-(Aminomethyl)cyclohexa-3,5-diene-1,2-dione
• CAS: 94099-46-4
• 化学式: C₇H₇NO₂
• mdl: MFCD19206529
• 分子量: 137.138
• InChiKey: CPXLXKCVXXXVJN-UHFFFAOYSA-N

物化性质

• 沸点：
  268.6±32.0 °C(Predicted)
• 密度：
  1.260±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  -1.2
• 重原子数：
  10
• 可旋转键数：
  1
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.142
• 拓扑面积：
  60.2
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  3,4-dioxybenzylamine 生成 4-氨甲基儿茶酚氢溴酸
  参考文献：
  名称：

  Enzymically Amplified Voltammetric Sensor for Microliter Sample Volumes of Salicylate

  摘要：

  A new voltammetric sensing strategy for salicylate employing two enzymes and applicable to microliter sample volumes is demonstrated, The method involves the use of the enzyme salicylate hydroxylase to convert salicylate to catechol, which is oxidized at a carbon electrode, The product of this oxidation reaction, o-quinone, is then reduced by a second enzyme, glucose oxidase, to regenerate catechol, Reoxidation of catechol results in a signal that is amplified due to repeated cycling of catechol molecules between the oxidized and reduced states, This chemistry is implemented in two configurations, (i) A paper disk into which both enzymes have been absorbed is mounted on a coplanar three electrode assembly for aqueous experiments, Determination of salicylate in a nonprescription dermatological product is demonstrated, (ii) A small solution volume confined directly on the coplanar electrodes is used for determination of salicylate in whole blood, The advantages of the use of two enzymes and of monitoring steady-state catalytic currents are discussed.

  DOI：

  10.1021/ac00107a022
• 作为产物：
  描述：

  4-氨甲基儿茶酚氢溴酸 生成 3,4-dioxybenzylamine
  参考文献：
  名称：

  JEON, HEE-KYOUNG;NOHTA, HITOSHI;OHKURA, YOSUKE, ANAL. SCI., 6,(1990) N, C. 677-682

  摘要：

  DOI：

文献信息

• JEON, HEE-KYOUNG;NOHTA, HITOSHI;OHKURA, YOSUKE, ANAL. SCI., 6,(1990) N, C. 677-682
  作者：JEON, HEE-KYOUNG、NOHTA, HITOSHI、OHKURA, YOSUKE

  DOI：——

  日期：——
• Enzymically Amplified Voltammetric Sensor for Microliter Sample Volumes of Salicylate
  作者：Thea J. Moore、Melissa J. Joseph、Barry W. Allen、Louis A. Coury

  DOI：10.1021/ac00107a022

  日期：1995.6.1

  A new voltammetric sensing strategy for salicylate employing two enzymes and applicable to microliter sample volumes is demonstrated, The method involves the use of the enzyme salicylate hydroxylase to convert salicylate to catechol, which is oxidized at a carbon electrode, The product of this oxidation reaction, o-quinone, is then reduced by a second enzyme, glucose oxidase, to regenerate catechol, Reoxidation of catechol results in a signal that is amplified due to repeated cycling of catechol molecules between the oxidized and reduced states, This chemistry is implemented in two configurations, (i) A paper disk into which both enzymes have been absorbed is mounted on a coplanar three electrode assembly for aqueous experiments, Determination of salicylate in a nonprescription dermatological product is demonstrated, (ii) A small solution volume confined directly on the coplanar electrodes is used for determination of salicylate in whole blood, The advantages of the use of two enzymes and of monitoring steady-state catalytic currents are discussed.