Methylheptylaethinylcarbinol | 6289-16-3

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: Methylheptylaethinylcarbinol
• 英文别名: 3-Hydroxy-3-methyl-dec-1-yn；2-Nonanol, 2-ethynyl-；3-methyldec-1-yn-3-ol
• CAS: 6289-16-3
• 化学式: C₁₁H₂₀O
• mdl: MFCD00489878
• 分子量: 168.279
• InChiKey: XWEVMQJXCXXZPU-UHFFFAOYSA-N

物化性质

• 沸点：
  200.2±8.0 °C(Predicted)
• 密度：
  0.879±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  3.3
• 重原子数：
  12
• 可旋转键数：
  7
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.818
• 拓扑面积：
  20.2
• 氢给体数：
  1
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  Methylheptylaethinylcarbinol 、 2-丁基噻吩噻吩 在 palladium dichloride 三乙胺 作用下， 以 甲醇 为溶剂， 反应 4.0h， 以79%的产率得到3-Methyl-1-thiophen-2-yldec-1-yn-3-ol
  参考文献：
  名称：

  Synthesis and anti-inflammatory activity of acetylenic thiophenes

  摘要：

  A series of acetylenic thiophene derivatives have been synthesized via Pd-catalyzed coupling reaction of 2-(butyltelluro)thiophene with a variety of terminal alkynes. These compounds showed good anti-inflammatory activity in the carrageenin-induced paw edema assay on rats. (C) 2001 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0040-4039(01)01703-8

文献信息

• New acetylenic furan derivatives: synthesis and anti-inflammatory activity
  作者：Gilson Zeni、Diogo S Lüdtke、Cristina W Nogueira、Rodrigo B Panatieri、Antonio L Braga、Claudio C Silveira、Hélio A Stefani、Joao B.T Rocha

  DOI：10.1016/s0040-4039(01)01984-0

  日期：2001.12

  A series of acetylenic furan derivatives have been synthesized via Pd-catalyzed coupling reactions of 2-(alkyltelluro)furan with several terminal alkynes. These compounds showed good anti-inflammatory activity in the carrageenin-induced rat paw edema assay. This represents a new and efficient method for the synthesis of pharmacologically active compounds.

  通过2-（烷基碲基）呋喃与几个末端炔烃的Pd催化的偶联反应，已经合成了一系列炔属呋喃衍生物。这些化合物在角叉菜胶诱导的大鼠爪水肿试验中显示出良好的抗炎活性。这代表了合成药理活性化合物的一种新的有效方法。
• CURABLE SILICON RUBBER COMPOSITION FOR LED PACKAGING
  申请人：Bluestar Silicones Shanghai Co. Ltd.

  公开号：EP3121236A1

  公开（公告）日：2017-01-25

  The present invention relates to a curable silicone rubber composition for LED enclosure, the process for preparing the same and the use thereof. Particularly, the compositions comprise at least one tackifier component D, which comprises: a) a alkenyl or hydrosilyl group containing isocyanurate compound E, and b) an adhesion-imparting ingredient having at least two functional groups selected from alkenyl, epoxy, alkoxy and hydrosilyl groups, which is consisting of polysiloxane F and optional coupling agents G.

  本发明涉及一种用于 LED 外壳的可固化硅橡胶组合物、其制备工艺及其用途。特别是，该组合物包含至少一种增粘剂组分 D，它包括 a) 含烯基或氢硅基的异氰脲酸酯化合物 E，以及 b) 具有至少两个选自烯基、环氧基、烷氧基和水硅烷基的官能团的增粘成分，由聚硅氧烷 F 和任选的偶联剂 G 组成。
• Curable silicone rubber composition for LED packaging
  申请人：ELKEM SILICONES SHANGHAI CO., LTD.

  公开号：US10400104B2

  公开（公告）日：2019-09-03

  A curable silicone rubber composition is described for an LED enclosure or packaging. A process for preparing the same and the use thereof are also described. Particularly, the compositions can include at least one tackifier component D, which includes: a) a alkenyl or hydrosilyl group including an isocyanurate compound E, and b) an adhesion-imparting ingredient having at least two functional groups selected from the group consisting of alkenyl, epoxy, alkoxy and hydrosilyl groups, which includes of polysiloxane F and optional coupling agents G.

  描述了一种用于 LED 外壳或包装的可固化硅橡胶组合物。还描述了制备该组合物的工艺及其用途。特别是，该组合物可以包括至少一种增粘剂成分 D，其中包括： a) 烯基或水硅基团，包括异氰脲酸酯化合物 E，以及 b) 具有至少两个官能团的增粘成分，这些官能团选自由烯基、环氧基、烷氧基和水硅 基组成的组，其中包括聚硅氧烷 F 和任选的偶联剂 G。
• Silicone composition and process useful for improving the crease resistance and abrasion resistance of airbags, intended for protecting a vehicle occupant
  申请人：Bluestar Silicones France SAS

  公开号：US10676574B2

  公开（公告）日：2020-06-09

  The general field of the invention is that of silicone coating compositions, in particular those of two-component or multi-component type, that can be crosslinked by polyaddition or hydrosilylation reactions to produce a support coated by a silicone elastomer as a thin layer. These silicone compositions, when they are crosslinked, are suitable, inter alia, as coatings, for example for the protection or mechanical reinforcement of various textile substrates such as for example fibrous, woven, knitted or nonwoven supports. The targeted objective is to provide a silicone elastomer coating composition that can be crosslinked by polyaddition reactions and that is useful in particular for applications in the field of inflatable safety bags for vehicles, or airbags, having, after crosslinking, optimum properties in terms of adhesion, thinness, lightness and crease and abrasion resistance, but also good mechanical properties. This silicone coating composition should also be easy to use and to apply.

  本发明的一般领域是有机硅涂层组合物，特别是那些双组分或多组分类型的组合物，它们可以通过加成反应或水硅烷化反应进行交联，从而产生一个由有机硅弹性体涂覆的薄层支撑物。这些有机硅组合物经交联后，除其他外，可用作涂层，例如用于保护或机械加固各种纺织基材，如纤维、机织、针织或无纺布支撑物。我们的目标是提供一种有机硅弹性体涂层组合物，这种组合物可以通过加成反应进行交联，尤其适用于汽车充气安全袋或安全气囊领域的应用，交联后具有最佳的粘附性、轻薄性、抗皱性和耐磨性，同时还具有良好的机械性能。这种有机硅涂层组合物还应易于使用和涂抹。
• Skin-adhesive item
  申请人：ELKEM SILICONES FRANCE SAS

  公开号：US10702625B2

  公开（公告）日：2020-07-07

  Items that can adhere to the skin for medical or paramedical use are described. Also described, is a skin-adhesive item.

  描述了可粘附在皮肤上用于医疗或辅助医疗的物品。还介绍了一种皮肤粘合剂。