1-Methyl-4-(2-phenyl-cyclopropanesulfonyl)-benzene

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 1-Methyl-4-(2-phenyl-cyclopropanesulfonyl)-benzene
• 英文别名: 1-Methyl-4-(2-phenylcyclopropyl)sulfonylbenzene
• 化学式: C₁₆H₁₆O₂S
• 分子量: 272.368
• InChiKey: JROXJJKKWYXUKZ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.5
• 重原子数：
  19
• 可旋转键数：
  3
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.25
• 拓扑面积：
  42.5
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  1-Methyl-4-(2-phenyl-cyclopropanesulfonyl)-benzene 在 palladium on activated charcoal 氢气 作用下， 以 甲醇 为溶剂， 反应 12.0h， 以63%的产率得到1-methyl-4-((3-phenylpropyl)sulfonyl)benzene
  参考文献：
  名称：

  Bellesia, Franco; Grandi, Romano; Pagnoni, Ugo M., Journal of Chemical Research, Miniprint, 1981, # 4, p. 1301 - 1309

  摘要：

  DOI：
• 作为产物：
  描述：

  1-(cinnamylsulfonyl)-4-methylbenzene 以 甲醇 为溶剂， 反应 24.0h， 以67%的产率得到1-Methyl-4-(2-phenyl-cyclopropanesulfonyl)-benzene
  参考文献：
  名称：

  Bellesia, Franco; Grandi, Romano; Pagnoni, Ugo M., Journal of Chemical Research, Miniprint, 1981, # 4, p. 1301 - 1309

  摘要：

  DOI：

文献信息

• [EN] COBALT-CATALYZED ASYMMETRIC CYCLOPROPANATION WITH DIAZOSULFONES<br/>[FR] CYCLOPROPANATION ASYMÉTRIQUE CATALYSÉE PAR COBALT AVEC DES DIAZOSULFONES
  申请人：UNIV SOUTH FLORIDA

  公开号：WO2009114849A1

  公开（公告）日：2009-09-17

  Asymmetric cyclopropanation of olefins with diazosulfones.

  烯烃与重氮磺酮的不对称环丙烷化反应。
• COBALT-CATALYZED ASYMMETRIC CYCLOPROPANATION WITH DIAZOSULFONES
  申请人：Zhang X. Peter

  公开号：US20100174104A1

  公开（公告）日：2010-07-08

  Asymmetric cyclopropanation of olefins with diazosulfones.

  烯烃与二磺酰肼的非对称环丙烷化。
• [(PhBP₃)Cu(PPh₃)] as a Surrogate of Tp^xCuL in Homogeneous Catalysis (PhBP₃ = PhB(CH₂PPh₂)₃; Tp^x = Hydrotrispyrazolylborate)
  作者：M. Ángeles Fuentes、Eleuterio Álvarez、Ana Caballero、Pedro J. Pérez

  DOI：10.1021/om201016b

  日期：2012.2.13

  The novel complexes [(PhBP3)Cu(L)] (PhBP3 = PhB(CH2PPh2)(3), L = PPh3, 1; L = tetrahydrofuran, 2) have been synthesized and spectroscopically and, in the case of 1, structurally characterized. Both complexes undergo dissociation of the PPh3 or THF ligand in solution to deliver the (PhBP3)Cu unit, similar in geometry to and isoelectronic with Tp(x)Cu (Tp(x) = trispyrazolylborate ligand). A complete study of the catalytic properties of 1 has shown that it can be considered as a surrogate of Tp(x)Cu. The study includes (a) olefin cyclopropanation, cyclopropenation, aziridination, halocarbon addition, and radical polymerization, (b) X-H (X = O, N) functionalization by carbene insertion, and (c) furan conversion into dihydropyridines. Since the observed activity is quite comparable to that already described for Tp(x)Cu complexes, this new catalytic system could become an alternative to the latter.
• BELLESIA F.; GRANDI R.; PAGNONI U. M.; TRAVE R., J. CHEM. RES. SYNOP., 1981, NO 4, 1301-1309/ J. CHEM. RES. MICROFICHE, 19+
  作者：BELLESIA F.、 GRANDI R.、 PAGNONI U. M.、 TRAVE R.

  DOI：——

  日期：——
• Bellesia, Franco; Grandi, Romano; Pagnoni, Ugo M., Journal of Chemical Research, Miniprint, 1981, # 4, p. 1301 - 1309
  作者：Bellesia, Franco、Grandi, Romano、Pagnoni, Ugo M.、Trave, Roberto

  DOI：——

  日期：——