3,7-dimethyloct-2E-ene-1,7,8-triol | 133156-15-7

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: 3,7-dimethyloct-2E-ene-1,7,8-triol
• 英文别名: 2,6-dimethyl-oct-6-ene-1,2,8-triol；2,6-Dimethyl-oct-6-en-1,2,8-triol；6-Octene-1,2,8-triol, 2,6-dimethyl-, (E)-；(E)-2,6-dimethyloct-6-ene-1,2,8-triol
• CAS: 133156-15-7
• 化学式: C₁₀H₂₀O₃
• 分子量: 188.267
• InChiKey: FLVKLMVQVSGAFI-WEVVVXLNSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.84
• 重原子数：
  13.0
• 可旋转键数：
  6.0
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.8
• 拓扑面积：
  60.69
• 氢给体数：
  3.0
• 氢受体数：
  3.0

反应信息

• 作为反应物：
  描述：

  3,7-dimethyloct-2E-ene-1,7,8-triol 在 sodium periodate 作用下， 以 四氢呋喃 、 水 为溶剂， 反应 0.5h， 以82%的产率得到7-oxo-3-methyloct-2E-en-1-ol
  参考文献：
  名称：

  Effective synthesis of 7-ketonor-?-geraniol, 7-ketonor-?-nerol, and 6,8-dioxabicyclooctanes from them

  摘要：

  A simple synthesis of 7-ketonor-alpha-nerol and -geraniol has been developed. It was shown that epoxidation of these allyl alcohols or the silyl ether of the latter proceeds stereospecifically, possibly via the stage of the corresponding unstable epoxides, and results in the formation of derivatives of 6,8-dioxabicyclo]3,2,1]octane.

  DOI：

  10.1007/bf00958565
• 作为产物：
  描述：

  8-hydroxygeranyl acetate 在 bis(acetylacetonate)oxovanadium 叔丁基过氧化氢 、 lithium aluminium tetrahydride 作用下， 以 四氢呋喃 、 甲苯 、 苯 为溶剂， 反应 2.66h， 生成 3,7-dimethyloct-2E-ene-1,7,8-triol
  参考文献：
  名称：

  Effective synthesis of 7-ketonor-?-geraniol, 7-ketonor-?-nerol, and 6,8-dioxabicyclooctanes from them

  摘要：

  A simple synthesis of 7-ketonor-alpha-nerol and -geraniol has been developed. It was shown that epoxidation of these allyl alcohols or the silyl ether of the latter proceeds stereospecifically, possibly via the stage of the corresponding unstable epoxides, and results in the formation of derivatives of 6,8-dioxabicyclo]3,2,1]octane.

  DOI：

  10.1007/bf00958565

文献信息

• Prileshajew, Chemische Berichte, 1909, vol. 42, p. 4813
  作者：Prileshajew

  DOI：——

  日期：——
• ZHENG, QIHUANG;SU, JINGYU;ZENG, LONGMEI, CHZHUNSHAN DASYUEH SYUEHBAO/TSZYZHAN KEHSYUEHBAN, 29,(1990) N, S. 106-110
  作者：ZHENG, QIHUANG、SU, JINGYU、ZENG, LONGMEI

  DOI：——

  日期：——
• BELYANKIN, A. V.;VESELOVSKIJ, V. V.;SHASHKOV, A. S.;MOISEENKOV, A. M., IZV. AN CCCP. CEP. XIM.,(1991) N, S. 846-852
  作者：BELYANKIN, A. V.、VESELOVSKIJ, V. V.、SHASHKOV, A. S.、MOISEENKOV, A. M.

  DOI：——

  日期：——
• Effective synthesis of 7-ketonor-?-geraniol, 7-ketonor-?-nerol, and 6,8-dioxabicyclooctanes from them
  作者：A. V. Belyankin、V. V. Veselovskii、A. S. Shashkov、A. M. Moiseenkov

  DOI：10.1007/bf00958565

  日期：1991.4

  A simple synthesis of 7-ketonor-alpha-nerol and -geraniol has been developed. It was shown that epoxidation of these allyl alcohols or the silyl ether of the latter proceeds stereospecifically, possibly via the stage of the corresponding unstable epoxides, and results in the formation of derivatives of 6,8-dioxabicyclo]3,2,1]octane.