3,3-二甲基环己烷甲醇 | 102369-67-5

• 分子结构分类: 有机化合物 - 有机氧化合物
• 中文名称: 3,3-二甲基环己烷甲醇
• 英文名称: (3,3-dimethylcyclohexyl)methanol
• 英文别名: (+/-)-3.3-Dimethyl-1-hydroxymethyl-cyclohexan；(3,3-Dimethyl-cyclohexyl)-methanol
• CAS: 102369-67-5
• 化学式: C₉H₁₈O
• mdl: MFCD21324307
• 分子量: 142.241
• InChiKey: VJZDBRGSBDTGKQ-UHFFFAOYSA-N

物化性质

• 沸点：
  89-92 °C(Press: 8 Torr)
• 密度：
  0.9198 g/cm3(Temp: 25 °C)
• 保留指数：
  1697

计算性质

• 辛醇/水分配系数(LogP)：
  2.6
• 重原子数：
  10
• 可旋转键数：
  1
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  20.2
• 氢给体数：
  1
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  3,3-二甲基环己烷甲醇 以68%的产率得到
  参考文献：
  名称：

  NOMURA, MASATO;FUJIHARA, YOSHIHITO, J. JAP. OIL CHEM. SOC., 36,(1987) N 7, 515-518

  摘要：

  DOI：
• 作为产物：
  描述：

  1-hydroxymethyl-3,3-dimethyl-cyclohex-1-ene 以75%的产率得到
  参考文献：
  名称：

  NOMURA, MASATO;FUJIHARA, YOSHIHITO, J. JAP. OIL CHEM. SOC., 36,(1987) N 7, 515-518

  摘要：

  DOI：

文献信息

• APOPTOSIS-INDUCING AGENTS FOR THE TREATMENT OF CANCER AND IMMUNE AND AUTOIMMUNE DISEASES
  申请人：AbbVie Inc.

  公开号：US20130096121A1

  公开（公告）日：2013-04-18

  Disclosed are compounds which inhibit the activity of anti-apoptotic Bc1-xL proteins, compositions containing the compounds and methods of treating diseases during which is expressed anti-apoptotic Bc1-xL protein.

  揭示了抑制抗凋亡Bc1-xL蛋白活性的化合物，含有这些化合物的组合物以及治疗在其中表达抗凋亡Bc1-xL蛋白的疾病的方法。
• N-SUBSTITUTED BENZAMIDES AND METHODS OF USE THEREOF
  申请人：XENON PHARMACEUTICALS INC.

  公开号：US20130317001A1

  公开（公告）日：2013-11-28

  The invention provides novel compounds having the general formula: and pharmaceutically acceptable salts thereof, wherein the variables R A , subscript n, ring A, X 2 , L, subscript m, X 1 , B, R 1 , R 2 , R 3 , R 4 , R 5 and R N have the meaning as described herein, and compositions containing such compounds and methods for using such compounds and compositions.

  本发明提供了具有下列一般式的新化合物及其药学上可接受的盐：其中变量RA、下标n、环A、X2、L、下标m、X1、B、R1、R2、R3、R4、R5和RN的含义如本文所述，并且包含这种化合物的组合物和使用这种化合物和组合物的方法。
• APOPTOSIS-INDUCED AGENTS FOR THE TREATMENT OF CANCER AND IMMUNE AND AUTOIMMUNE DISEASES
  申请人：AbbVie Inc.

  公开号：US20160206611A1

  公开（公告）日：2016-07-21

  Disclosed are compounds which inhibit the activity of anti-apoptotic Bcl-xL proteins, compositions containing the compounds and methods of treating diseases during which is expressed anti-apoptotic Bcl-xL protein.

  本发明涉及一种抑制抗凋亡Bcl-xL蛋白活性的化合物，含有该化合物的组合物以及治疗表达抗凋亡Bcl-xL蛋白的疾病的方法。
• Inhibition of dark spots growth in organic electroluminescent devices
  作者：M.K Fung、Z.Q Gao、C.S Lee、S.T Lee

  DOI：10.1016/s0009-2614(00)01407-x

  日期：2001.1

  Humidity-induced oxidation has been considered as a major cause for the growth of dark spots in organic electroluminescent devices. In this Letter, we found that a layer of 100 nn thick calcium deposited on top of the magnesium:silver (Mg:Ag) cathode can slow down the growth rate of dark spots. Further experiments verified that calcium not in direct contact with the cathode could not protect the dark spots against growing. This excludes the possibility that the protective function of calcium derives solely from its action as a moisture-resistive agent. In contrast, calcium functions as a sacrificial metal forming a galvanic couple with the magnesium electrode such that calcium would oxidize in preference to the Mg:Ag. (C) 2001 Elsevier Science B.V. All rights reserved.
• NOMURA, MASATO;FUJIHARA, YOSHIHITO, J. JAP. OIL CHEM. SOC., 36,(1987) N 7, 515-518
  作者：NOMURA, MASATO、FUJIHARA, YOSHIHITO

  DOI：——

  日期：——