5-[(2E)-2-octen-1-yl]dihydro-2(3H)-furanone | 60551-23-7

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 内酯类
• 英文名称: 5-[(2E)-2-octen-1-yl]dihydro-2(3H)-furanone
• 英文别名: (E)-6-dodecen-4-olide；Dihydro-5-(2-octenyl)-2(3H)-furanone；5-[(E)-oct-2-enyl]oxolan-2-one
• CAS: 60551-23-7
• 化学式: C₁₂H₂₀O₂
• 分子量: 196.29
• InChiKey: QFXOXDSHNXAFEY-VOTSOKGWSA-N

物化性质

• 沸点：
  311.2±11.0 °C(Predicted)
• 密度：
  0.950±0.06 g/cm3(Predicted)
• LogP：
  3.105 (est)
• 保留指数：
  1701;1701;1655;1661

计算性质

• 辛醇/水分配系数(LogP)：
  3.6
• 重原子数：
  14
• 可旋转键数：
  6
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.75
• 拓扑面积：
  26.3
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  3-壬烯-1-醇,(3E)- 在 2,2,6,6-四甲基哌啶氧化物 、 四氯化钛 作用下， 以 二氯甲烷 为溶剂， 生成 5-[(2E)-2-octen-1-yl]dihydro-2(3H)-furanone
  参考文献：
  名称：

  通过向醛中添加改性的同烯酸钛，可轻松获得芳香活性不饱和γ-内酯

  摘要：

  均一Reformatsky反应（其中将酯的金属均烯酸酯添加到醛中）适用于从不饱和的可烯醇化的醛中生产γ-内酯。通过使用高纯钛酸钛，一步合成11种不同的γ-内酯，从容易获得的醛中获得中等至良好的收率。特别地，该方法允许快速制备一系列在双键的位置和构型上不同的C 12不饱和γ-内酯。这些参考化合物将用于鉴定黄油中以前未知的内酯。提供了合成内酯的色谱，光谱和感官描述。

  DOI：

  10.1021/jf104711x

文献信息

• BITTER TASTE MODIFIERS INCLUDING SUBSTITUTED 1-BENZYL-3-(1-(ISOXAZOL-4-YLMETHYL)-1H-PYRAZOL-4-YL)IMIDAZOLIDINE-2,4-DIONES AND COMPOSITIONS THEREOF
  申请人：SENOMYX, INC.

  公开号：US20160376263A1

  公开（公告）日：2016-12-29

  The present invention includes compounds and compositions known to modify the perception of bitter taste, and combinations of said compositions and compounds with additional compositions, compounds, and products. Exemplary compositions comprise one or more of the following: cooling agents; inactive drug ingredients; active pharmaceutical ingredients; food additives or foodstuffs; flavorants, or flavor enhancers; food or beverage products; bitter compounds; sweeteners; bitterants; sour flavorants; salty flavorants; umami flavorants; plant or animal products; compounds known to be used in pet care products; compounds known to be used in personal care products; compounds known to be used in home products; pharmaceutical preparations; topical preparations; cannabis-derived or cannabis-related products; compounds known to be used in oral care products; beverages; scents, perfumes, or odorants; compounds known to be used in consumer products; silicone compounds; abrasives; surfactants; warming agents; smoking articles; fats, oils, or emulsions; and/or probiotic bacteria or supplements.

  本发明涵盖已知用于改变苦味感知的化合物和组合物，以及所述组合物和化合物与额外的组合物、化合物和产品的组合。示例组合物包括以下一种或多种：冷却剂；无活性药物成分；活性药用成分；食品添加剂或食品；调味剂或调味增强剂；食品或饮料产品；苦味化合物；甜味剂；苦味剂；酸味调味剂；咸味调味剂；鲜味调味剂；植物或动物产品；已知用于宠物护理产品中的化合物；已知用于个人护理产品中的化合物；已知用于家用产品中的化合物；制药制剂；局部制剂；大麻衍生或与大麻相关的产品；已知用于口腔护理产品中的化合物；饮料；香味、香水或除臭剂；已知用于消费品中的化合物；硅化合物；磨料；表面活性剂；发热剂；吸烟物品；脂肪、油脂或乳化剂；和/或益生菌或补充剂。
• COMPOUNDS USEFUL AS MODULATORS OF TRPM8
  申请人：Senomyx, Inc.

  公开号：US20170096418A1

  公开（公告）日：2017-04-06

  The present disclosure relates to compounds which are useful as cooling sensation compounds.

  本公开涉及作为冷感化合物有用的化合物。
• 5-ALKENYL-2-OXO-TETRAHYDROFURANE DERIVATIVES AS FLAVORING COMPOUNDS
  申请人：Aeberhardt Kasia

  公开号：US20130034646A1

  公开（公告）日：2013-02-07

  The present invention relates to the use of a compound of having the following formula: wherein either 1 or 2 of the dotted lines represent a double bond, in order to provide or enhance buttery, creamy, green, fatty and/or milky note to flavors and foods.

  本发明涉及使用具有以下公式的化合物：其中点线中的1或2表示双键，以提供或增强风味和食品的奶油、奶香、青草、脂肪和/或乳香。
• Fermentation process for preparing 10-hydroxy-C18-carboxylic acid and gamma-dodecalactone derivatives
  申请人：INTERNATIONAL FLAVORS & FRAGRANCES INC.

  公开号：EP0578388A2

  公开（公告）日：1994-01-12

  Described is a fermentation process for preparing 10-hydroxy-C18-carboxylic acid derivative containing compositions containing compounds defined according to the structure : and gamma-dodecalactone derivative-containing compositions containing compounds defined according to the structure : wherein the dashed lines represent the same or different carbon-carbon bonds; with each of the dashed lines representing a carbon-carbon single bond or a carbon-carbon double bond, products produced thereby and organoleptic uses thereof including uses for augmenting, enhancing or imparting aromas or flavors to or in consumable materials including but not limited to perfume compositions, colognes, perfumed articles, foodstuffs, chewing gums, beverages, toothpastes, hair preparations, tobacco compositions and smoking tobacco articles.

  所描述的是一种发酵工艺，用于制备含有 10-羟基-C18-羧酸衍生物的组合物，该组合物含有根据......结构定义的化合物： 和含有γ-十二内酯衍生物的组合物，其中含有根据结构......定义的化合物： 其中虚线代表相同或不同的碳-碳键；每条虚线代表一个碳-碳单键或一个碳-碳双键，由此生产的产品及其感官用途，包括用于增加、提高或赋予消费品的香气或味道，消费品包括但不限于香水组合物、古龙水、香水制品、食品、口香糖、饮料、牙膏、头发制剂、烟草组合物和烟草制品。
• Fresh cheese products containing biogenerated flavor components and methods for producing
  申请人：KRAFT FOODS HOLDINGS, INC.

  公开号：EP1769687A1

  公开（公告）日：2007-04-04

  The invention provides for the manufacture of cheese products enhanced with a natural, biogenerated flavoring system. The natural flavoring system described herein may be used with various types of cheese and dairy products. In one embodiment, the system may be used in the production of flavor enhanced fresh cheese or cream cheese. In another embodiment, the system may be used in the production of low-fat cheese pmducts, such as low-fat cream cheese.

  本发明提供了一种天然生物调味系统，可用于制造奶酪产品。本文所述的天然调味系统可用于各种类型的奶酪和乳制品。在一个实施方案中，该系统可用于生产风味增强型新鲜奶酪或奶油奶酪。在另一个实施方案中，该系统可用于生产低脂奶酪产品，例如低脂奶油奶酪。