3,5-二甲基环己甲醇 | 68480-16-0

• 分子结构分类: 有机化合物 - 有机氧化合物
• 中文名称: 3,5-二甲基环己甲醇
• 英文名称: 3,5-Dimethylcyclohexanemethanol
• 英文别名: (3,5-dimethylcyclohexyl)methanol
• CAS: 68480-16-0
• 化学式: C₉H₁₈O
• 分子量: 142.24
• InChiKey: GEVHTUNKMMCORO-UHFFFAOYSA-N

物化性质

• LogP：
  2.863 (est)

计算性质

• 辛醇/水分配系数(LogP)：
  2.4
• 重原子数：
  10
• 可旋转键数：
  1
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  20.2
• 氢给体数：
  1
• 氢受体数：
  1

文献信息

• [EN] CYCLOALKYL AND HETEROCYCLOALKYL SUBSTITUTED BENZOTHIOPHENES AS THERAPEUTIC AGENTS<br/>[FR] BENZOTHIOPHENES SUBSTITUTES PAR CYCLOALKYLE ET HETEROCYCLOALKYLE, UTILES COMME AGENTS THERAPEUTIQUES
  申请人：WARNER LAMBERT CO

  公开号：WO2004108713A1

  公开（公告）日：2004-12-16

  The present invention provides benzo[b]thiophenes of Formula (I) wherein R1, R2, R3, and L have any of the values defined therefor in the specification, and pharmaceutically acceptable salts thereof, that are useful as agents in the treatment of diseases and conditions, including inflammatory diseases, cardiovascular diseases, and cancers. Also provided are pharmaceutical compositions comprising one or more compounds of Formula (I).

  本发明提供了公式（I）中的苯并[b]噻吩，其中R1、R2、R3和L具有规范中定义的任何值，以及其药学上可接受的盐，这些化合物可用作治疗疾病和病况的药剂，包括炎症性疾病、心血管疾病和癌症。还提供了包含一个或多个公式（I）化合物的药物组合物。
• [EN] HALO SUBSTITUTED BENZO`B! THIOPHENES WITH PI3K INHIBITORY ACTIVITY AS THERAPEUTIC AGENTS<br/>[FR] BENZO[B]THIOPHENES HALO-SUBSTITUES A ACTIVITE INHIBITRICE DE PI3K UTILES COMME AGENTS THERAPEUTIQUES
  申请人：WARNER LAMBERT CO

  公开号：WO2005023800A1

  公开（公告）日：2005-03-17

  The present invention provides benzo[b]thiophenes of Formula (I), wherein R3, R4, R5, R6, R7, Y, and L have any of the values defined therefor in the specification, and pharmaceutically acceptable salts thereof, that are useful as agents in the treatment of diseases and conditions, including inflammatory diseases, cardiovascular diseases, and cancers. Also provided are pharmaceutical compositions comprising one or more compounds of Formula (I)

  本发明提供了公式（I）中的苯并[b]噻吩，其中R3、R4、R5、R6、R7、Y和L具有规范中定义的任何值，以及其药用盐，这些化合物可用作治疗疾病和病况的药物，包括炎症性疾病、心血管疾病和癌症的药物。还提供了包含一个或多个公式（I）化合物的药物组合物。
• Halo substituted benzo[b]thiophenes as therapeutic agents
  申请人：Connolly K. Michael

  公开号：US20050096350A1

  公开（公告）日：2005-05-05

  The present invention provides benzo[b]thiophenes of Formula I: wherein R 3 , R 4 , R 5 , R 6 , R 7 , Y, and L have any of the values defined therefor in the specification, and pharmaceutically acceptable salts thereof, that are useful as agents in the treatment of diseases and conditions, including inflammatory diseases, cardiovascular diseases, and cancers. Also provided are pharmaceutical compositions comprising one or more compounds of Formula I.

  本发明提供了公式I中的苯并[b]噻吩：其中R3、R4、R5、R6、R7、Y和L具有规范中定义的任何值，以及其药学上可接受的盐，这些化合物可用作治疗炎症性疾病、心血管疾病和癌症等疾病和病况的药物。还提供了包含一个或多个公式I化合物的制药组合物。
• METHOD FOR PRODUCING INTERNAL MOLD RELEASE AGENT FOR OPTICAL MATERIAL, INTERNAL MOLD RELEASE AGENT FOR OPTICAL MATERIAL, AND POLYMERIZABLE COMPOSITION INCLUDING THE SAME
  申请人：Mitsui Chemicals, Inc.

  公开号：EP2497791A1

  公开（公告）日：2012-09-12

  The process for producing an internal mold release agent for an optical material of the present invention includes a step of heating, to a range of 80°C to 140°C, a composition including (a) a phosphoric ester compound, and (b) an alcohol compound containing an aliphatic alcohol having 1 to 10 carbon atoms and/or aromatic alcohol, when the total amount of (a) and (b) is 100% by weight, the alcohol compound (b) is included in an amount equal to or more than 2.5% by weight.

  本发明的光学材料内脱模剂的生产工艺包括以下步骤：将包括(a) 磷酸酯化合物和(b) 含有 1 至 10 个碳原子的脂肪醇和/或芳香醇的醇类化合物的组合物加热至 80°C 至 140°C，当(a)和(b)的总量为 100%（按重量计）时，醇类化合物(b)的含量等于或大于 2.5%（按重量计）。
• Cycloalkyl and heterocycloalkyl substituted benzothiophenes as therapeutic agents
  申请人：Connolly Michael

  公开号：US20050020630A1

  公开（公告）日：2005-01-27

  The present invention provides benzo[b]thiophenes of Formula I: wherein R 1 , R 2 , R 3 , and L have any of the values defined therefor in the specification, and pharmaceutically acceptable salts thereof, that are useful as agents in the treatment of diseases and conditions, including inflammatory diseases, cardiovascular diseases, and cancers. Also provided are pharmaceutical compositions comprising one or more compounds of Formula I.

  本发明提供了式 I 的苯并[b]噻吩： 其中 R 1 , R 2 , R 3 及其药学上可接受的盐，可作为治疗疾病和病症的药物，包括炎症性疾病、心血管疾病和癌症。还提供了包含一种或多种式 I 化合物的药物组合物。