Dispiro[2,1,2,1]octan-4,8-dion | 59078-46-5

• 分子结构分类: 有机化合物 - 有机氧化合物
• 英文名称: Dispiro[2,1,2,1]octan-4,8-dion
• 英文别名: Dispiro[2.1.2.1]octane-4,8-dione；dispiro[2.1.25.13]octane-4,8-dione
• CAS: 59078-46-5
• 化学式: C₈H₈O₂
• 分子量: 136.15
• InChiKey: VQIUDMMYMVRNLG-UHFFFAOYSA-N

物化性质

• 熔点：
  180-181 °C
• 沸点：
  323.2±17.0 °C(Predicted)
• 密度：
  1.36±0.1 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  0.6
• 重原子数：
  10
• 可旋转键数：
  0
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.75
• 拓扑面积：
  34.1
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  Dispiro[2,1,2,1]octan-4,8-dion 在 五氯化磷 作用下， 以 四氯化碳 为溶剂， 反应 4.0h， 以57%的产率得到4,4,8,8-Tetrachloro-dispiro[2.1.2.1]octane
  参考文献：
  名称：

  Strelow, Thomas; Voss, Juergen; Baum, Werner, Zeitschrift fur Naturforschung, B: Chemical Sciences, 1993, vol. 48, # 9, p. 1288 - 1290

  摘要：

  DOI：
• 作为产物：
  描述：

  6-cyclopropylidene-5-oxaspiro<2.3>hexan-4-one 在 三乙烯二胺 、 叔丁醇 作用下， 以 二氯甲烷 为溶剂， 生成 Dispiro[2,1,2,1]octan-4,8-dion
  参考文献：
  名称：

  Wulferding, Andreas; Jankowski, Joerg H.; Hoffmann, H. Martin R., Chemische Berichte, 1994, vol. 127, # 7, p. 1275 - 1282

  摘要：

  DOI：

文献信息

• Low temperature ketene preparations using nitrosyltetracarbonylchromium (-II) anion
  作者：A.P. Masters、T.S. Sorensen

  DOI：10.1016/s0040-4039(01)93492-6

  日期：1989.1
• Hoffmann, H. M. R.; Walenta, Angela; Eggert, Ulrike, Angewandte Chemie, 1985, vol. 97, # 7, p. 599 - 600
  作者：Hoffmann, H. M. R.、Walenta, Angela、Eggert, Ulrike、Schomburg, Dietmar

  DOI：——

  日期：——
• Trispiro[2.1.2.1.2.1]dodecane-4,8,12-trione and other oligomers of carbonylcyclopropane. The organozinc route
  作者：H. Martin R. Hoffmann、Ulrike Eggert、Angela Walenta、Edeltraut Weineck、Dietmar Schomburg、Rudolf Wartchow、Frank H. Allen

  DOI：10.1021/jo00287a022

  日期：1989.12
• Studies dealing with the excited-state behavior of substituted 8-oxabicyclo[3.2.1]oct-6-en-2-ones
  作者：Albert Padwa、Lin Zhi、Glen E. Fryxell

  DOI：10.1021/jo00003a032

  日期：1991.2

  A series of 8-oxabicyclo [3.2.1]oct-6-en-2-ones was prepared by the rhodium(II)-catalyzed cyclization-cycloaddition reaction of alpha-diazopentanedione with various alkynes. The photochemical behavior of these oxabicyclic enones was investigated. Both direct and sensitized photolysis cleanly results in a 1,3-acyl shift. A slower, secondary photoprocess involving intramolecular hydrogen atom transfer and intramolecular cycloaddition of the resulting ketene was also uncovered. The photobehavior of the closely related 9-oxabenzocycloheptene system was also examined. The initially formed 1,3-sigmatropic rearranged product was found to undergo a novel 1,4-methoxyl migration on extended photolysis. The photochemistry of the homologous 7-oxabicyclo[2.2.1]hepten-2-one was studied. The results obtained can be interpreted in terms of an initial Norrish type I cleavage. The resulting diradical either couples to give the 1,3-acyl shift product or undergoes bond fragmentation, giving products derived from a stepwise retro-Diels-Alder reaction.
• Nuennecke, Dirk; Voss, Juergen; Adiwidjaja, Gunadi, Zeitschrift fur Naturforschung, B: Chemical Sciences, 1997, vol. 52, # 2, p. 259 - 262
  作者：Nuennecke, Dirk、Voss, Juergen、Adiwidjaja, Gunadi

  DOI：——

  日期：——