2-Methyl-2-prop-2-enylbutanedioic acid | 113661-33-9

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: 2-Methyl-2-prop-2-enylbutanedioic acid
• CAS: 113661-33-9
• 化学式: C₈H₁₂O₄
• 分子量: 172.181
• InChiKey: FNZBRJIFXCWRFS-UHFFFAOYSA-N

物化性质

• 沸点：
  279.8±20.0 °C(Predicted)
• 密度：
  1.187±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  0.7
• 重原子数：
  12
• 可旋转键数：
  5
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  74.6
• 氢给体数：
  2
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  2-Methyl-2-prop-2-enylbutanedioic acid 在 ammonium hydroxide 、 sodium hydride 、 N,N-二异丙基乙胺 作用下， 以 四氢呋喃 、 水 为溶剂， 反应 23.17h， 生成 3-Allyl-1-benzyloxymethyl-4-[1-hydroxy-meth-(Z)-ylidene]-3-methyl-pyrrolidine-2,5-dione
  参考文献：
  名称：

  Battersby, Alan R.; Westwood, Steven W., Journal of the Chemical Society. Perkin transactions I, 1987, p. 1679 - 1688

  摘要：

  DOI：
• 作为产物：
  描述：

  2-甲基-4-戊酸 、 lithium bromoacetate 生成 2-Methyl-2-prop-2-enylbutanedioic acid
  参考文献：
  名称：

  Battersby, Alan R.; Westwood, Steven W., Journal of the Chemical Society. Perkin transactions I, 1987, p. 1679 - 1688

  摘要：

  DOI：

文献信息

• BATTERSBY, ALAN R.;WESTWOOD, STEVEN W., J. CHEM. SOC. PERKIN TRANS.,(1987) N 8, 1679-1687
  作者：BATTERSBY, ALAN R.、WESTWOOD, STEVEN W.

  DOI：——

  日期：——
• BIOCONVERSION OF SHORT-CHAIN HYDROCARBONS TO FUELS AND CHEMICALS
  申请人：Gonzales Ramon

  公开号：US20180355394A1

  公开（公告）日：2018-12-13

  An engineered microorganism(s) with novel pathways for the conversion of short-chain hydrocarbons to fuels and chemicals (e.g. carboxylic acids, alcohols, hydrocarbons, and their alpha-, beta-, and omega-functionalized derivatives) is described. Key to this approach is the use of hydrocarbon activation enzymes able to overcome the high stability and low reactivity of hydrocarbon compounds through the cleavage of an inert C—H bond. Oxygen-dependent or oxygen-independent activation enzymes can be exploited for this purpose, which when combined with appropriate pathways for the conversion of activated hydrocarbons to key metabolic intermediates, enables the generation of product precursors that can subsequently be converted to desired compounds through established pathways. These novel engineered microorganism(s) provide a route for the production of fuels and chemicals from short chain hydrocarbons such as methane, ethane, propane, butane, and pentane.
• Bioconversion of Short-Chain Hydrocarbons to Fuels and Chemicals
  申请人：Gonzalez Ramon

  公开号：US20200347423A1

  公开（公告）日：2020-11-05

  An engineered microorganism(s) with novel pathways for the conversion of short-chain hydrocarbons to fuels and chemicals (e.g. carboxylic acids, alcohols, hydrocarbons, and their alpha-, beta-, and omega-functionalized derivatives) is described. Key to this approach is the use of hydrocarbon activation enzymes able to overcome the high stability and low reactivity of hydrocarbon compounds through the cleavage of an inert C—H bond. Oxygen-dependent or oxygen-independent activation enzymes can be exploited for this purpose, which when combined with appropriate pathways for the conversion of activated hydrocarbons to key metabolic intermediates, enables the generation of product precursors that can subsequently be converted to desired compounds through established pathways. These novel engineered microorganism(s) provide a route for the production of fuels and chemicals from short chain hydrocarbons such as methane, ethane, propane, butane, and pentane.
• [EN] BIOCONVERSION OF SHORT-CHAIN HYDROCARBONS TO FUELS AND CHEMICALS<br/>[FR] BIOCONVERSION D'HYDROCARBURES À CHAÎNE COURTE EN CARBURANTS ET PRODUITS CHIMIQUES
  申请人：UNIV RICE WILLIAM M

  公开号：WO2016161043A1

  公开（公告）日：2016-10-06

  An engineered microorganism(s) with novel pathways for the conversion of short- chain hydrocarbons to fuels and chemicals (e.g. carboxylic acids, alcohols, hydrocarbons, and their alpha-, beta-, and omega-functionalized derivatives) is described. Key to this approach is the use of hydrocarbon activation enzymes able to overcome the high stability and low reactivity of hydrocarbon compounds through the cleavage of an inert C-H bond. Oxygen-dependent or oxygen-independent activation enzymes can be exploited for this purpose, which when combined with appropriate pathways for the conversion of activated hydrocarbons to key metabolic intermediates, enables the generation of product precursors that can subsequently be converted to desired compounds through established pathways. These novel engineered microorganism(s) provide a route for the production of fuels and chemicals from short chain hydrocarbons such as methane, ethane, propane, butane, and pentane.
• Battersby, Alan R.; Westwood, Steven W., Journal of the Chemical Society. Perkin transactions I, 1987, p. 1679 - 1688
  作者：Battersby, Alan R.、Westwood, Steven W.

  DOI：——

  日期：——