A large number of N-aminodipeptides compounds have been obtained via a Mitsunobu protocol performed in Solution or by solid-phase synthesis. The oligomerization of some of them has been studied in solution or on solid support leading to the formation of 1:1[alpha:alpha-N-amino]mers. (C) 2008 Elsevier Ltd. All rights reserved.
Investigation of NH–π (Ph) interaction in the 1:1[α:α-N-amino]mers using 1H NMR and FTIR absorption spectroscopy
1H NMR and FTIR experiments performed on the 1:1[α:α-N-amino]mersseries let us to point out a rare NH–π interaction between the carbamidic NH of the i residue and the phenyl group of a phenylalanine residue located at i+2.
在1:1 [α:α- N-氨基] mers系列上进行的1 H NMR和FTIR实验使我们指出i残基的氨基甲酸酯NH与苯丙氨酸残基的苯基之间罕见的NH-π相互作用位于我+2。
Elaboration and structural studies of cyclo 1:1-[α/α-N-amino]mers