3-(4-甲酰基苯氧基)丙烷-1-磺酸 | 58464-26-9

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯酚醚
• 中文名称: 3-(4-甲酰基苯氧基)丙烷-1-磺酸
• 英文名称: 3-(4-formylphenoxy)propane-1-sulfonic acid
• CAS: 58464-26-9
• 化学式: C₁₀H₁₂O₅S
• 分子量: 244.268
• InChiKey: IRFQBJRIWXLIFP-UHFFFAOYSA-N

物化性质

• 密度：
  1.382±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  0.1
• 重原子数：
  16
• 可旋转键数：
  6
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.3
• 拓扑面积：
  89
• 氢给体数：
  1
• 氢受体数：
  5

反应信息

• 作为反应物：
  描述：

  2-乙酰基吡啶 、 3-(4-甲酰基苯氧基)丙烷-1-磺酸 在 乙酰胺 、 ammonium acetate 、 sodium hydroxide 作用下， 以 水 为溶剂， 反应 2.0h， 以82%的产率得到3-(4-([2,2';6',2'']terpyridin-4'-yl)phenoxy)propane-1-sulfonic acid
  参考文献：
  名称：

  Reusable Polymer-Supported Terpyridine Copper Complex for [3+2] Huisgen Cycloaddition in Water

  摘要：

  A polymer-supported terpyridine copper(I) complex was prepared and found to promote the Huisgen [3+2] cycloaddition reaction between azides and alkynes in water to give the corresponding triazoles with up to 87% isolated yield. This catalyst was recovered and reused several times without any loss in catalytic activity.

  DOI：

  10.3987/com-09-11872
• 作为产物：
  描述：

  1,3-丙烷磺内酯 、 对羟基苯甲醛 在 potassium hydroxide 作用下， 以 异丙醇 为溶剂， 反应 3.0h， 以84%的产率得到3-(4-甲酰基苯氧基)丙烷-1-磺酸
  参考文献：
  名称：

  Reusable Polymer-Supported Terpyridine Copper Complex for [3+2] Huisgen Cycloaddition in Water

  摘要：

  A polymer-supported terpyridine copper(I) complex was prepared and found to promote the Huisgen [3+2] cycloaddition reaction between azides and alkynes in water to give the corresponding triazoles with up to 87% isolated yield. This catalyst was recovered and reused several times without any loss in catalytic activity.

  DOI：

  10.3987/com-09-11872

文献信息

• Suzuki–Miyaura Cross-Coupling Reaction in Water with Polymer-Supported Terpyridine Palladium Complex Under Aerobic Conditions
  作者：Toshimasa Suzuka、Takuya Nagamine、Kazuhito Ogihara、Matsutake Higa

  DOI：10.1007/s10562-010-0422-0

  日期：2010.11

  A polymer-supported terpyridine Pd(II) complex was prepared and found to promote the Suzuki-Miyaura coupling reaction in water. Thus, terpyridine ligand was prepared from p-hydroxybenzaldehyde, propane sultone, and 2-acetylpyridine according to the reported procedures. Immobilization of terpyridine ligand onto a polystyrene-poly(ethylene glycol) (PS-PEG) resin through ionic bonds to sulfonate group took place and the complexation of PS-PEG-terpyridine ligand with Pd(II) underwent to give PS-PEG-terpyridine-Pd(II) complex. This polymeric catalyst showed high catalytic activity and high reusability for the Suzuki-Miyaura coupling reaction.
• US3955984A
  申请人：——

  公开号：US3955984A

  公开（公告）日：1976-05-11
• US4111697A
  申请人：——

  公开号：US4111697A

  公开（公告）日：1978-09-05
• US4268622A
  申请人：——

  公开号：US4268622A

  公开（公告）日：1981-05-19
• Reusable Polymer-Supported Terpyridine Copper Complex for [3+2] Huisgen Cycloaddition in Water
  作者：Toshimasa Suzuka、Kazumasa Ooshiro、Ken’yu Kina

  DOI：10.3987/com-09-11872

  日期：——

  A polymer-supported terpyridine copper(I) complex was prepared and found to promote the Huisgen [3+2] cycloaddition reaction between azides and alkynes in water to give the corresponding triazoles with up to 87% isolated yield. This catalyst was recovered and reused several times without any loss in catalytic activity.